Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells by Marjan Nokhbehsaim, Sigrun Eick, Andressa Vilas Boas Nogueira, Per Hoffmann, Stefan Herms, Holger Fröhlich, Søren Jepsen, Andreas Jäger, Joni Augusto Cirelli, James Deschner

“…Eight of these genes could be confirmed by real-time PCR: NAMPT induced a significant upregulation of EGR1, MMP-1, SYT7, ITPKA, CCL2, NTM, IGF2BP3, and NRP1. NAMPT also increased significantly the MMP-1 and CCL2 protein synthesis. …”
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Nucleotides Regulate Secretion of the Inflammatory Chemokine CCL2 from Human Macrophages and Monocytes by K. R. Higgins, W. Kovacevic, L. Stokes

“…CCL2 is an important inflammatory chemokine involved in monocyte recruitment to inflamed tissues. …”
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The role and therapeutic targeting of the CCL2/CCR2 signaling axis in inflammatory and fibrotic diseases by Shan Guo, Qi Zhang, Yingjie Guo, Xiaoyan Yin, Peng Zhang, Tao Mao, Zibin Tian, Xiaoyu Li

Subjects: “…CCL2…”
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HCFC-141b (CH3CCl2F) Emission Estimates for 2000–2050 in Eastern China by Dayu Zhang, Jing Wu, Zehua Liu, Tong Wang, Yueling Zhang, Dongmei Hu, Lin Peng

“…Abstract HCFC-141b (CH3CCl2F) has dual environmental impacts on ozone depletion and climate change, with the ozone depletion potential of 0.11 and the global warming potential of 782, and its emissions has attracted international attention. …”
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Corrigendum to “PIPKIγ Regulates CCL2 Expression in Colorectal Cancer by Activating AKT-STAT3 Signaling” by JunLi Xue, XiaoXiao Ge, Wei Zhao, Liqiong Xue, Congqi Dai, Fengjuan Lin, Wei Peng

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Insulin Resistance, Inflammation, and Obesity: Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism by Anna Rull, Jordi Camps, Carlos Alonso-Villaverde, Jorge Joven

“…Main topics cover the relationship between MCP-1/CCL2, insulin resistance, inflammation, obesity, and related metabolic disturbances.…”
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EZH2 Might Affect Macrophage Chemotaxis and Anti-Inflammatory Factors by Regulating CCL2 in Dental Pulp Inflammation by Ziqi Hu, Yingyi Chen, Jie He, He Liu, Tianqian Hui

“…The expressions of anti-inflammatory cytokine interleukins (IL-4 and IL-10) and transforming growth factor-β (TGF-β) in HDPCs which were treated by EZH2 complex, CCL2 complex, and CCL2 antibody were examined by quantitative real-time polymerase chain reaction (q-PCR). …”
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CCL-2 and CXCL-8: Potential Prognostic Biomarkers of Acute Kidney Injury after a Bothrops atrox Snakebite by Juliana Costa Ferreira Neves, Hiochelson Najibe Santos Ibiapina, Fábio Magalhães-Gama, Jacqueline Almeida Gonçalves Sachett, Iran Mendonça Silva, Kerolaine Fonseca Coelho, Eliane Campos Alves, Andréa Monteiro Tarragô, Luiz Carlos de Lima Ferreira, Adriana Malheiro, Wuelton Marcelo Monteiro, Allyson Guimarães Costa

“…The soluble immunological molecules (CXCL-8, CCL-5, CXCL-9, CCL-2, CXCL-10, IL-6, TNF, IL-2, IL-10, IFN-γ, IL-4, and IL-17A) were quantified using cytometric bead array. …”
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Disruption of tumor-intrinsic PGAM5 increases anti-PD-1 efficacy through the CCL2 signaling pathway by Yan Li, Hong Wang, Xiaoyang Li, Yuan He, Huiquan Liu, Dong Han, Ting Mei, Yixuan Li, Zilong Xu, Xiaoying Wei, Jianguo Wang, Peijie Zhou, Yuwen Wang, Ziye Li, Junhao Ning, Anlin Wang, Jingjing Cheng, Dong Qian

“…Tumor-intrinsic PGAM5 deficiency mediated mitochondria fusion and reduced cytosolic mtDNA stress which attenuated TLR9 activation and downstream NF-κB-regulated CCL2 secretion. Furthermore, disruption of tumor-intrinsic Pgam5 significantly facilitated CD8+ T cells activation and improved anti-programmed cell death protein-1 therapeutic efficacy with macrophages depletion compromising synergistic antitumor immune response.Conclusion Our results shed light on the effect of tumor mitochondria dynamics on TAMs in tumor microenvironment. …”
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Bindarit attenuates neuroinflammation after subarachnoid hemorrhage by regulating the CCL2/CCR2/NF-κB pathway by Yanting Yao, Qiaowei Wu, Kaikun Yuan, Pei Wu, Chao Xu, Zhiyong Ji, Weishi Xu, Hongli Yu, Anyu Xu, Yanchen Liu, Huaizhang Shi

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Electroacupuncture alleviates paclitaxel-induced peripheral neuropathy by reducing CCL2-mediated macrophage infiltration in sensory ganglia and sciatic nerve by Yuanyuan Li, Ruoyao Xu, Muyan Chen, Kaige Zheng, Huimin Nie, Chengyu Yin, Boyu Liu, Yan Tai, Junying Du, Jie Wang, Jianqiao Fang, Boyi Liu

“…EA reduced CCL2 overproduction by DRG neurons and reduced macrophage infiltration. …”
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背根神经节 STAT3/CCL2 信号通路在泰素诱导慢性疼痛中的作用 by 廖维勇, 王勇, 黄文君, 唐名杰

“…【目的】研究转录因子STAT3通过上调背根神经节趋化因子CCL2的表达介导泰素诱导慢性疼痛的机制。【方法】66只大鼠随机分成6组，包括：溶剂对照组（V）、泰素组（T）、鞘内注射CCL2中和性抗体+泰素组（A+T）、鞘内注射S3I-201+泰素组（S+T）、泰素+溶剂组（T+R）、鞘内注射C188-9+泰素组（C+T）。…”
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脊髓CCL2在瑞芬太尼诱导的大鼠痛觉过敏中的作用机制

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Assessment of urine CCL2 as a potential diagnostic biomarker for acute kidney injury and septic acute kidney injury in intensive care unit patients by Yuan Peng, Qin Wang, Fang Jin, Tao Tao, Qihong Qin

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PDPN+ cancer‐associated fibroblasts enhance gastric cancer angiogenesis via AKT/NF‐κB activation and the CCL2‐ACKR1 axis by Zhenxiong Zhao, Hui Sun, Yingxue Liu, Yanqiu Zhang, Xin Wang, Xu Wang, Cong Tan, Shujuan Ni, Weiwei Weng, Meng Zhang, Lei Wang, Dan Huang, Wenchao Gu, Jinjia Chang, Weiqi Sheng, Mi‐die Xu

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Circulating CD3+CD8+ T Lymphocytes as Indicators of Disease Status in Patients With Early Breast Cancer by Han‐Kun Chen, Yi‐Ling Chen, Wei‐Pang Chung, Zhu‐Jun Loh, Kuo‐Ting Lee, Hui‐Ping Hsu

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SUMO modified ETV1 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by facilitating CCL2 transcription in esophageal squamous cell carcinoma cells by Tianci Han, Xiaoqi Guo, Junwei Xie, Wei Tong, Liang Zhang

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Prophylactic Subacute Administration of Zinc Increases CCL2, CCR2, FGF2, and IGF-1 Expression and Prevents the Long-Term Memory Loss in a Rat Model of Cerebral Hypoxia-Ischemia by Victor Manuel Blanco-Alvarez, Guadalupe Soto-Rodriguez, Juan Antonio Gonzalez-Barrios, Daniel Martinez-Fong, Eduardo Brambila, Maricela Torres-Soto, Ana Karina Aguilar-Peralta, Alejandro Gonzalez-Vazquez, Constantino Tomás-Sanchez, I. Daniel Limón, Jose R. Eguibar, Araceli Ugarte, Jeanett Hernandez-Castillo, Bertha Alicia Leon-Chavez

“…These results might be explained by the induction of neural plasticity because of the expression of CCL2 and growth factors.…”
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Common biomarkers of idiopathic pulmonary fibrosis and systemic sclerosis based on WGCNA and machine learning by Ning Shan, Yu Shang, Yaowu He, Zhe Wen, Shangwei Ning, Hong Chen

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Exploring the Role of C-C Motif Chemokine Ligand-2 Single Nucleotide Polymorphism in Pulmonary Tuberculosis: A Genetic Association Study from North India by Sanjay K. Biswas, Mayank Mittal, Ekata Sinha, Vandana Singh, Nidhi Arela, Bharat Bajaj, Pramod K. Tiwari, Vishwa M. Katoch, Keshar K. Mohanty

“…The C-C motif chemokine ligand-2 (CCL2) was evidenced to be associated with tuberculosis susceptibility in some ethnic groups. …”
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