TET2 downregulation enhances the antitumor efficacy of CD19 CAR T cells in a preclinical model by Yeongrin Kim, Moonjung Jeun, Heung Kyoung Lee, Ji U Choi, Simon Park, Chi Hoon Park

Subjects: “…CAR T cell…”
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Several factors that predict the outcome of large B‐cell lymphoma patients who relapse/progress after chimeric antigen receptor (CAR) T‐cell therapy can be identified before cell a... by Alice Sýkorová, František Folber, Kamila Polgárová, Heidi Móciková, Juraj Ďuraš, Kateřina Steinerová, Aleš Obr, Adriana Heindorfer, Miriam Ladická, Ľubica Lukáčová, Erika Čellárová, Ivana Plameňová, David Belada, Andrea Janíková, Marek Trněný, Tereza Jančárková, Vít Procházka, Andrej Vranovský, Margaréta Králiková, Jan Vydra, Lukáš Smolej, Ľuboš Drgoňa, Martin Sedmina, Eva Čermáková, Robert Pytlík

Subjects: “…CAR T‐cell failure…”
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Capivasertib enhances chimeric antigen receptor T cell activity in preclinical models of B cell lymphoma by Hui-Ju Hsieh, Ryan Urak, Mary C. Clark, Larry W. Kwak, Stephen J. Forman, Xiuli Wang

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Taming Variability in T-Cell Mechanosensing by Paula J. Schultheiss, Aarya Pulkundwar, Wangqi Li, Lance C. Kam

Subjects: “…CAR T-cell therapies…”
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Choice of activation protocol impacts the yield and quality of CAR T cell product, particularly with older individuals by Palak H Mehta, Gemma S Trollope, Patrick Leung, Shivali Savita Chinni, Anna Iasinskaia, Aaron J Harrison, Hannah Hughes‐Parry, Misty R Jenkins, Michael H Kershaw, Anthony Jaworowski, Clare Y Slaney, Rachel M Koldej, David S Ritchie, Kylie M Quinn

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NKG2D/CD28 chimeric receptor boosts cytotoxicity and durability of CAR-T cells for solid and hematological tumors by Xia Teng, Shance Li, Chaoting Zhang, Huirong Ding, Zhihua Tian, Yuge Zhu, Ting Liu, Guanyu Zhang, Kang Sun, Huimin Xie, Jiaxin Tu, Zheming Lu

Subjects: “…CAR-T cell therapy…”
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Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors by Safwaan H. Khan, Safwaan H. Khan, Yeonjoo Choi, Mysore Veena, Mysore Veena, John K. Lee, John K. Lee, Daniel Sanghoon Shin, Daniel Sanghoon Shin

Subjects: “…CAR T cell…”
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The CD64/CD28/CD3ζ chimeric receptor reprograms T-cell metabolism and promotes T-cell persistence and immune functions while triggering antibody-independent and antibody-dependent... by Sara Caratelli, Francesca De Paolis, Domenico Alessandro Silvestris, Silvia Baldari, Illari Salvatori, Apollonia Tullo, Giulia Lanzilli, Aymone Gurtner, Alberto Ferri, Cristiana Valle, Simona Padovani, Valeriana Cesarini, Tommaso Sconocchia, Loredana Cifaldi, Roberto Arriga, Giulio Cesare Spagnoli, Soldano Ferrone, Adriano Venditti, Piero Rossi, Graziano Pesole, Gabriele Toietta, Giuseppe Sconocchia

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CAR-T Cell Therapy: Managing Side Effects and Overcoming Challenges by Maryam Golmohammadi, Negar Noorbakhsh, Maria Kavianpour

Subjects: “…car-t cell…”
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Establishing a GMP-compliant manufacturing process and phase-appropriate analytics for early development of a FiCAR T-cell product with a novel CAR spacer by Annu Luostarinen, Arja Vuorela, Erja Kerkelä, Mimmi Patrikoski, Annika Kotovuori, Jan Koski, Jonna Ahoniemi, Kaarina Lähteenmäki, Jenni Lehtisalo, Terhi Oja, Henrik Paavilainen, Anu Autio, Marie Nyman, Veera Nikoskelainen, Virginie Kergourlay, Endrit Elbasani, Bert van Veen, Anil Thotakura, Hector Monzo, Päivi M. Ojala, Matti Korhonen, Heidi Hongisto, Anita Laitinen

Subjects: “…CAR T-cell…”
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Research on strategies to inhibit CAR-T cell exhaustion by FU Qiongyu, HAO Xinbao, TAO Shi

Subjects: “…car-t cell|t cell exhaustion|mechanisms of exhaustion|governance policies…”
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Chimeric Antigen Receptor (CAR) T Cells Releasing Soluble SLAMF6 Isoform 2 Gain Superior Anti-Cancer Cell Functionality in an Auto-Stimulatory Fashion by Dennis Christoph Harrer, Tim Schlierkamp-Voosen, Markus Barden, Hong Pan, Maria Xydia, Wolfgang Herr, Jan Dörrie, Niels Schaft, Hinrich Abken

Subjects: “…CAR T cell…”
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Revolutions at the frontline of multiple myeloma treatment: lessons and challenges to finding a cure by Jeries Kort, Jeries Kort, Andrea Rivera, Andrea Rivera, Sindhuja Senigarapu, James J. Driscoll, James J. Driscoll, James J. Driscoll

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Influence of CAR T-cell therapy associated complications by Mohammad Mussab Umair, Xun Lai, YuanBo Xue, Hong Yao

Subjects: “…CAR T-cell…”
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Enhancing CAR T‐cell therapy manufacturing efficiency through semi‐automated bioprocessing by Jason Isaacson, Prajakta Bhanap, Nicholas Putnam, Jasmine Padilla, Nujhat Fatima, Max Dotson, Danny Hayoun, Moloud Ahmadi, Gertrude Nonterah, Yongchang Ji

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Innovative Approaches in the Treatment of Pancreatic Cancer: The Role of CAR T-Cell Therapy by Jakub Kuźniar, Emilia Gabriela Chrzanowska, Julia Szlążek, Adam Jan Ząbek, Michalina Zagalska, Marta Turek, Tomasz Tamborski, Adam Grzebinoga, Barbara Roguska, Anna Katarzyna Kuźniar

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CAR-T cell therapies: patient access and affordability solutions by Elisabete Gonçalves

Subjects: “…CAR-T cell therapy…”
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Target selection and clinical chimeric antigen receptor T cell activity against solid tumors by Eric vonHofe, Yanping Yang, Moonsoo M. Jin

Subjects: “…CAR T cell…”
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Advancing Chimeric Antigen Receptor T-Cell Therapy for Acute Myeloid Leukemia: Current Limitations and Emerging Strategies by Daniela Damiani, Mario Tiribelli

Subjects: “…CAR T-cell therapy…”
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The potential of chimeric antigen receptor -T cell therapy for endocrine cancer by Ruonan Yu, Xiaoyu Ji, Ping Zhang, Hao Zhang, Huiling Qu, Wenwu Dong

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