A Comparative Study of the Metabolic and Skeletal Response of C57BL/6J and C57BL/6N Mice in a Diet-Induced Model of Type 2 Diabetes by Elizabeth Rendina-Ruedy, Kelsey D. Hembree, Angela Sasaki, McKale R. Davis, Stan A. Lightfoot, Stephen L. Clarke, Edralin A. Lucas, Brenda J. Smith

“…This study investigated the long-term metabolic and skeletal consequences of two commonly used C57BL/6 substrains to a high fat (HF) diet. Male C57BL/6J, C57BL/6N, and the negative control strain, C3H/HeJ, mice were fed a control or HF diet for 24 wks. …”
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Optimization of the cholesterol gallstone model in C57BL/6 mice and evaluation of Lactobacillus intervention effects by Cong Wang, Ting Jiang, Lvwang Ye, Mengyan Du, Fang Liu

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Faecalibacterium prausnitzii regulates carbohydrate metabolic functions of the gut microbiome in C57BL/6 mice by Peiling Geng, Ni Zhao, Yufan Zhou, Reuben S. Harris, Yong Ge

“…Multiomic approaches were used to profile the impact of UT1 on the gut microbiome and associated metabolic activity of C57BL/6 mice at homeostasis. Both 16S rRNA and metagenomic sequencing demonstrated that oral administration of UT1 resulted in profound microbial compositional changes including a significant enrichment of Lactobacillus, Bifidobacterium, and Turicibacter. …”
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Postnatal Hematopoiesis and Gut Microbiota in NOD Mice Deviate from C57BL/6 Mice by Dina Silke Malling Damlund, Stine Broeng Metzdorff, Jane Preuss Hasselby, Maria Wiese, Mia Lundsager, Dennis Sandris Nielsen, Karsten Stig Buschard, Axel Kornerup Hansen, Hanne Frøkiær

“…Furthermore, a distinct splenic cell profile high in a granulocytic phenotype was evident in the neonatal NOD mice whereas neonatal C57BL/6 mice showed a profile rich in monocytes. Neonatal expression of Reg3g and Muc2 in the gut was deviating in NOD mice and coincided with fewer bacteria attaching to the Mucosal surface in NOD compared to C57BL/6 mice.…”
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The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice by Vasiliy V. Kurilin, Julia N. Khantakova, Valeriy P. Tereschenko, Julia A. Lopatnikova, Irina A. Obleukhova, Sergey V. Sennikov

“…Tolerogenic factors were found to have different effects on DCs C57Bl/6 mice. In C57Bl/6 mice, BAY 11-7082 alone had no effect on the expression of DC maturation molecules (CD80, CD86). …”
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Effects of female sexual chemosignals on mucosal immunity in BALB/c and C57BL/6 male mice by G. V. Kontsevaya, E. A. Litvinova, M. P. Moshkin

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Chromosome 1 Sequence Analysis of C57BL/6J-Chr1KM Mouse Strain by Fuyi Xu, Tianzhu Chao, Yiyin Zhang, Shixian Hu, Yuxun Zhou, Hongyan Xu, Junhua Xiao, Kai Li

“…In this study, we sequenced the genome of the C57BL/6J-Chr1KM (B6-Chr1KM) strain, the chromosome 1 (Chr 1) of which was derived from one KM mouse. …”
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Sex differences of molecular mechanisms of insulin sensitivity in young and adult C57BL/6J mice by T. V. Yakovleva, A. Yu. Kazantseva, E. N.  Makarova, N. M. Bazhan

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Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice by Yang Long, Dan Jia, Libin Wei, Yumei Yang, Haoming Tian, Tao Chen

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Effects of ginseng dietary supplementation on a high-Fat diet-induced obesity in C57BL/6 Mice by Jia-Ni Lin, Pei-Sheng Lee, Nai-Wen Mei, An-Chin Cheng, Roch-Chui Yu, Min-Hsiung Pan

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MPTP Neurotoxicity and Testosterone Induce Dendritic Remodeling of Striatal Medium Spiny Neurons in the C57Bl/6 Mouse by Eleni Antzoulatos, Michael W. Jakowec, Giselle M. Petzinger, Ruth I. Wood

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Studyng the effects of Cantharellus cibarius fungi on Opisthorchis felineus trematode and on parasite host - C57BL/6 inbred mice by M. A. Tsyganov, G. B. Vishnevetskaya, T. P. Kukina, I. V. Sorokina, M. N. Lvova, M. A. Protsenko, N. E. Kostina, D. F. Avgustinovich

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Comparison of age-related decline in C57BL/6J and CB6F1J male mice. by Gerald Yu Liao, Christina Pettan-Brewer, Warren Ladiges

“…We conducted a detailed exploration of behavioral and physiological differences between male C57BL/6J and male CB6F1J mice across various age groups (4, 12, 20, 24 months). …”
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Exercise-induced anxiety impairs local and systemic inflammatory response and glucose metabolism in C57BL/6J mice by I. Gálvez, M.C. Navarro, S. Torres-Piles, L. Martín-Cordero, M.D. Hinchado, E. Ortega

“…Material and methods: C57BL/6J mice were randomly allocated into sedentary or exercised groups, where the anxiety-inducing exercise protocol was based on a 14-day consecutive program of swimming in water at 38 °C. …”
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Exendin-4 Improves Diabetic Kidney Disease in C57BL/6 Mice Independent of Brown Adipose Tissue Activation by Shu Fang, Yingying Cai, Fuping Lyu, Hongbin Zhang, Chunyan Wu, Yanmei Zeng, Cunxia Fan, Shaozhou Zou, Yudan Zhang, Ping Li, Ling Wang, YaomingXue, Meiping Guan

“…This study is to verify the role of BAT involved in renal benefits of exendin-4 in diabetes mellitus (DM). Methods. In vivo, C57BL/6 mice were randomly divided into nondiabetic (control) and diabetic groups (DM). …”
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Baseline gene expression in BALB/c and C57BL/6 peritoneal macrophages influences but does not dictate their functional phenotypes by Carlos M. Restrepo, Carlos M. Restrepo, Alejandro Llanes, Alejandro Llanes, Lizzi Herrera, Esteban Ellis, Esteban Ellis, Esteban Ellis, Iliana Quintero, Patricia L. Fernández, Patricia L. Fernández

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Intake of S-Methylmethionine Alters Glucose Metabolism and Hepatic Gene Expression in C57BL/6J High-Fat-Fed Mice by Mariana Buranelo Egea, Gavin Pierce, Neil Shay

“…Thus, the objective of this work was to evaluate the inclusion of SMM as a dietary supplement in C57BL/6J high-fat-fed mice to verify whether this compound alone would be responsible for these positive effects. …”
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Apigenin ameliorates imiquimod-induced psoriasis in C57BL/6J mice by inactivating STAT3 and NF-κB by Xianshe Meng, Shihong Zheng, Zequn Yin, Xuerui Wang, Daigang Yang, Tingfeng Zou, Huaxin Li, Yuanli Chen, Chenzhong Liao, Zhouling Xie, Xiaodong Fan, Jihong Han, Yajun Duan, Xiaoxiao Yang

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Effect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice by Lawrence Coppey, Bao Lu, Craig Gerard, Mark A. Yorek

“…In the prevention study glucose tolerance was impaired in DIO C57Bl/6J mice and improved with ilepatril or enalapril. …”
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Metabolic Profiling by UPLC–Orbitrap–MS/MS of Liver from C57BL/6 Mice with DSS-Induced Inflammatory Bowel Disease by Zhongquan Xin, Zhenya Zhai, Hongrong Long, Fan Zhang, Xiaojun Ni, Jinping Deng, Lunzhao Yi, Baichuan Deng

“…First, a refined and translationally relevant model of DSS chronic colitis in C57BL/6 mice was established, and cecropin A and antibiotics were used as interventions. …”
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