Cytokine Profile of Mouse Vaginal and Uterus Lymphocytes at Estrus and Diestrus by Maria C. Lopez, Margaret A. Stanley

“…Two different mice strains, BALB/c and C57BL/6 mice, were used. The most relevant finding was the increase in the proportion of vaginal cells secreting IFN-γ at diestrus in both strains of mice. …”
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Involvement of Cytokines in the Pathogenesis of Hypersensitivity Pneumonitis: Evaluation of Immunotherapeutic Measures in a Mouse Model by Michel Denis, Marie Bédard, Jacques Gagnon, Yvon Cormier, Michel Laviolette

“…C57BL/6 inbred strain mice were instilled intranasally with 150 μg/day of the actinomycete Faeni rectivirgula three days a week as a model of farmer's lung disease. …”
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Angelica acutiloba Kitagawa Extract Attenuates DSS-Induced Murine Colitis by Jong-Chan Jang, Kang Min Lee, Seong-Gyu Ko

“…Colitis was induced by 4% dextran sulfate sodium (DSS) in the drinking water of male C57BL/6 mice, for 7 consecutive days. Oral administration of AAK extract (500 mg/kg/day) significantly alleviated DSS-induced symptoms such as anorexia, weight loss, events of diarrhea or bloody stools, and colon shortening. …”
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FAM134B-mediated endoplasmic reticulum autophagy protects against cisplatin-induced spiral ganglion neuron damage by Fan Wang, Yue Xu, Yajie Wang, Qian Liu, Yanan Li, Weiwei Zhang, Huiming Nong, Junhong Zhang, Hao Zhao, Huaqian Yang, Lingchuan Guo, Jianfeng Li, Jianfeng Li, Hong Li, Qianqian Yang

“…The present study was designed to determine whether FAM134B is expressed in SGNs of C57BL/6 mice and, if so, to explore the potential function of FAM134B in Cis-induced SGN damage in vitro.MethodsMiddle turns of neonatal murine cochleae were cultured and treated with 30 μM Cis in vitro. …”
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Novel insights into palatal shelf elevation dynamics in normal mouse embryos by Jeremy P. Goering, Michael Moedritzer, Marta Stetsiv, Dona Greta Isai, Brittany M. Hufft-Martinez, An J. Tran, Zaid Umar, Madison K. Rickabaugh, Paul Keselman, Munish Chauhan, Pamela V. Tran, William M. Brooks, William M. Brooks, Kenneth J. Fischer, Andras Czirok, Andras Czirok, Irfan Saadi, Irfan Saadi

“…Time-restricted pregnancies with a 1-h resolution showed that in 97% of C57BL/6J embryos, the PS were unelevated at E14.0. …”
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Systemic regulation of retinal medium-chain fatty acid oxidation repletes TCA cycle flux in oxygen-induced retinopathy by Almut Heinken, John M. Asara, Gopalan Gnanaguru, Charandeep Singh

“…Using an oxygen-induced retinopathy (OIR) mouse model, we investigated the metabolic differences between OIR-resistant BALB/cByJ and OIR susceptible C57BL/6J strains at system levels to understand the molecular underpinnings that potentially contribute to hyperoxia-induced vascular abnormalities in the neural retina. …”
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Exercise reduced the formation of new adipocytes in the adipose tissue of mice in vivo. by Timothy D Allerton, Jonathan J Savoie, Mark D Fitch, Marc K Hellerstein, Jacqueline M Stephens, Ursula White

“…To determine if exercise affects in vivo adipocyte formation, fifty-two, sixteen-week-old C57BL/6J mice were allowed access to unlocked running wheels [Exercise (EX) group; n = 13 males, n = 13 females] or to locked wheels [Sedentary (SED) group; n = 13 males, n = 13 females] for 4-weeks. …”
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Exercise as a mean to reverse the detrimental effect of high-fat diet on bone’s fracture characteristics by Ilias Doulamis, Despina N. Perrea, Panagiotis E. Chatzistergos, Athanasios S. Mitousoudis, Stavros K. Kourkoulis

“…A total of 26 adult male C57bl/6J mice were randomly assigned into three groups: (A) Control group (n=6), (B) High-fat diet group (n=10), (C) High-fat diet and exercise group (n=10). …”
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Use of eXIA 160 XL for Contrast Studies in Micro–Computed Tomography: Experimental Observations by Inneke Willekens, Nico Buls, Michel De Maeseneer, Tony Lahoutte, Johan de Mey

“…The purpose of this study was to evaluate the time course of contrast enhancement of spleen, liver, and blood using eXIA 160 XL in healthy mice. eXIA 160 XL was intravenously injected in C57bl/6 mice ( n = 12) at a dose of 0.1 mL/20 g (16 mg iodine [I]/20 g) ( n = 6) or 0.2 mL/20 g (32 mg I/20 g) ( n = 6). …”
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Study on the Dynamic Biological Characteristics of Sca-1+ Hematopoietic Stem and Progenitor Cell Senescence by Shan Geng, Xin-Yi Mu, Xiong-Bin Chen, Ji-Ying Hou, Dao-Yong Jia, Chun-Yan Xu, Ya-Ping Wang

“…The researches in the dynamic changes of the progress of HSCs aging are very limited and necessary. In this study, male C57BL/6 mice were divided into 5 groups by age. We found that the superoxide damage of HSPCs started to increase from the middle age (6 months old), with notably reduced antioxidation ability. …”
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Prenatal gene-environment interactions mediate the impact of advanced maternal age on mouse offspring behavior by Marta Marlena Ziętek, Aneta Jaszczyk, Adrian Mateusz Stankiewicz, Silvestre Sampino

“…Here, we investigated the effects of advanced maternal age on offspring health and behavior in two genetically divergent mouse strains: the BTBR T+ Itpr3tf/J (BTBR) mouse model of idiopathic autism, and the C57BL/6 J (B6) control strain, as a model of genetic variability. …”
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Interferon-gamma: A Potent Antiviral Agent Targeting Macrophages Infected with LP-BM5 Murine Leukemia Virus, the Causative Agent of 'AIDS' in Mice by Jens J Kort, Julie L Eiseman

“…LP-BM5 murine leukemia virus (MuLV) infection of C57BL/6 mice and cell lines has been used to optimize therapy directed against macrophages. …”
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High-Fat Diet-Induced Neuropathy of Prediabetes and Obesity: Effect of PMI-5011, an Ethanolic Extract of Artemisia dracunculus L. by Pierre Watcho, Roman Stavniichuk, David M. Ribnicky, Ilya Raskin, Irina G. Obrosova

“…., on neuropathy in high-sfat diet-fed mice, a model of prediabetes and obesity developing oxidative stress and proinflammatory changes in peripheral nervous system. C57Bl6/J mice fed high-fat diet for 16 weeks developed obesity, moderate nonfasting hyperglycemia, nerve conduction deficit, thermal and mechanical hypoalgesia, and tactile allodynia. …”
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Effectiveness of the tetrapeptide HAEE: an innovative approach to Alzheimer's treatment in experimentation by Evgenii A. Patrakhanov

“…Materials and Methods: The study was conducted on three experimental groups consisting of male APPswe/PS1dE9/Blg mice on a mixed genetic background with C57Bl6/Chg animals. Each group included 10 mice. At the baseline (point 0), peptides and drugs were administered to two groups of animals aged 6 months. …”
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Animal Models of Diabetic Neuropathy: Progress Since 1960s by Md. Shahidul Islam

“…A numbers of animal models of diabetic and PDN have been developed in the last several decades such as streptozotocin-induced diabetic rat models, conventional or genetically modified or high-fat diet-fed C57BL/Ks (db/db) mice models, streptozotocin-induced C57BL6/J and ddY mice models, Chinese hamster neuropathic model, rhesus monkey PDN model, spontaneously diabetic WBN/Kob rat model, L-fucose-induced neropathic rat model, partial sciatic nerve ligated rat model, nonobese diabetic (NOD) mice model, spontaneously induced Ins2 Akita mice model, leptin-deficient (ob/ob) mice model, Otsuka Long-Evans Tokushima Fatty (OLETF) rat model, surgically-induced neuropathic model, and genetically modified Spontaneously Diabetic Torii (SDT) rat model, none of which are without limitations. …”
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Normalization of Deviant Behavior in Muc2+/+ Mice through Dietary Incorporation of Bacillus subtilis Spores by Maryana Morozova, Alexander Alekseev, Arsalan Saeidi, Ekaterina Litvinova

“…The addition of kanamycin-resistant strain Bacillus subtilis BS20 spores to the diet of Muc2+/+ mice for 3 weeks at 107 CFU/g led to a change in behavior and cytokine levels in the gut compared to control C57BL/6 mice. Furthermore, a drop in serotonin and a rise in tyrosine were identified in the blood serum. …”
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Discrimination of Anti-Donor Response in Allogeneic Transplantation Using an Alloreactive T-Cell Detection Assay by Ryosuke Arata, Naoki Tanimine, Akhmet Seidakhmetov, Kentaro Ide, Yuka Tanaka, Hideki Ohdan

“…On day 7, donor-reactive CD8+ T-cell proportions were lower in the tolerance model (BALB/c to C3H/HeJ) than in the rejection model (BALB/c to C57BL/6); conventional proliferation readout after 4 days of MLR could not distinguish these responses. …”
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Spinal Cord Pathology in Alpha-Synuclein Transgenic Mice by Sonja Mendritzki, Saskia Schmidt, Teresa Sczepan, Xin-Ran Zhu, Daniel Segelcke, Hermann Lübbert

“…In previous studies with transgenic C57BL/6 mice overexpressing α-synuclein carrying the mutations A53T and A30P found in Parkinson's disease or with a parkin-null background, we reported severe mitochondrial impairments in neurons and to a larger extent in glial cells of the mesencephalon. …”
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Intestinal microbiota dysbiosis contributes to the liver damage in subchronic arsenic-exposed mice by Dong Ling, Luo Peng, Zhang Aihua

“…However, comprehensive analysis of gut flora dysbiosis in arsenic-induced hepatotoxicity is lacking. Herein, C57BL/6 mice are exposed to arsenic (1, 2, or <sc>4 mg/kg)</sc> for 12 weeks, after which fecal microbiota transplantation (FMT) study is conducted to confirm the roles of the intestinal microbiome in pathology. …”
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Mechanism of Bushen Zhuangjin Decoction to Promote BMSCs Homing and Protect Articular Cartilage in Mice by the SDF-1/CXCR4 Axis by HUANG Yanfeng, MA Dezun, FU Changlong, YE Jinxia, HUANG Yunmei, LI Xihai

“…ObjectiveTo investigate the mechanism by which Bushen Zhuangjin Decoction (BZD) regulates the SDF-1/CXCR4 axis to promote the homing of bone marrow mesenchymal stem cells (BMSCs) and protect articular cartilage in mice, thereby providing experimental basis for the rehabilitation treatment of knee osteoarthritis (KOA).Methods(1) In the animal experiment, 30 SPF male C57BL/6 mice, 8 weeks old, were selected and randomly divided into sham group, model group and BZD group, with 10 mice in each group. …”
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