Effects of repeated intragastric administrations with heat-inactivated Mycobacterium aurum DSM 33539 on the stress-induced aggravation of dextran sulfate sodium (DSS) colitis in C57BL/6N mice by Dominik Langgartner, Anna-Lena J. Weiss, Mattia Amoroso, John D. Sterrett, Christopher A. Lowry, Christopher A. Lowry, Christopher A. Lowry, Christopher A. Lowry, Christopher A. Lowry, Stefan O. Reber, Stefan O. Reber

“…Therefore, the aim of the current study was to assess whether repeated i.g. administrations of a heat-inactivated preparation of Mycobacterium aurum DSM 33539 prior to 19 days of chronic subordinate colony housing (CSC) are able to ameliorate the negative effects of this preclinically validated mouse model for chronic psychosocial stress on subsequent dextran sulfate sodium (DSS) colitis in male C57BL/6N mice. The results of the present study show that repeated i.g. administrations of M. aurum DSM 33539 have stabilizing effects on the composition of the gut microbiome, indicated by the findings that M. aurum DSM 33539 prevented CSC-induced increases in the relative abundances of the colitogenic phyla Desulfobacterota and Deferribacterota. …”
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Effect of gonadectomy and estradiol on the expression of insulin signaling cascade genes in female and male mice by T. V. Iakovleva, N. E. Kostina, E. N. Makarova, N. M. Bazhan

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Sex differences in the expression of lipid oxidation and glucose uptake genes in muscles of fasted mice by N. A. Feofanova, T. V. Yakovleva, E. N. Makarova, N. M. Bazhan

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Mutation yellow in agouti loci prevents age-related increase of skeletal muscle genes regulating free fatty acids oxidation by Y. V. Piskunova, A. Y. Kazantceva, A. V. Baklanov, N. M. Bazhan

Subjects: “…c57bl/6j mice…”
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Verification of Lactobacillus brevis tolerance to simulated gastric juice and the potential effects of postbiotic gamma-aminobutyric acid in streptozotocin-induced diabetic mice by Amro Abdelazez, Heba Abdelmotaal, Smith Etareri Evivie, Maha Bikheet, Rokayya Sami, Hassan Mohamed, Xiangchen Meng

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System of plasminogen regulators in the skin of intact uPA gene-knockout C57BL/6-PlautmI.IBug-This Plau6FDhu/GFDhu mice and in a model of chronic neurogenic pain by E. M. Frantsiyants, E. I. Surikova, I. V. Kaplieva, I. V. Neskubina, L. S. Kozlova, V. A. Bandovkina, L. K. Trepitaki, V. V. Pozdnyakova

“…In CNP, PG regulators in uPA-deficient mice were inhibited compared to the background, excluding uPAR in males and females. The comparison with C57BL/6 mice demonstrated that the CNP model resulted in the uPA system state very similar to that in intact uPA-deficient C57BL/6-PlautmI.IBug-ThisPlau6FDhu/GFDhu animals. …”
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Novel soybean peptide iglycin ameliorates insulin resistance of high-fat diet fed C57BL/6J mice and differentiated 3T3L1 adipocytes with improvement of insulin signaling and mitochondrial function by Yinghuan Wu, Ran Zhao, Minxia Li, Huiyun Li, Zhengwang Chen, Yanying Zhao

“…Thereafter, iglycin reduced fasting blood glucose and restored insulin sensitivity of C57BL/6J mice on a high-fat diet with increased phosphorylation of insulin receptor substrate 1 (IRS1) and AKT in adipose tissue. …”
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Fragrant olive (Osmanthus fragrans Lour.) flower extract attenuates dexamethasone-induced muscle atrophy through stimulation of PI3K/Akt pathway in C2C12 myotubes and C57BL/6 mice by Taeuk Kim, Seungok Lee, Sein Lee, Hyejung Han, Chul-Hong Kim, Dong-Woo Lee, Jae-Kwan Hwang

“…In this study, in vitro and in vivo experiments were performed using C2C12 myotubes and C57BL/6 mice treated with dexamethasone to investigate the anti-atrophic effects of Osmanthus fragrans water extract (OFWE). …”
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Impact of sex on the adaptation of adult mice to long consumption of sweet-fat diet by N. M. Bazhan, T. V. Iakovleva, A. D. Dubinina, E. N. Makarova

Subjects: “…c57bl/6j mice…”
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Antitumor effect of a new human epidermal growth factor receptor inhibitor by O. I. Kit, I. P. Kodonidi, E. M. Frantsiyants, I. V. Kaplieva, A. A. Glushko, L. K. Trepitaki, E. I. Surikova, V. A. Bandovkina, Yu. A. Pogorelova, I. V. Neskubina, O. V. Bykadorova, E. V. Serdyukova

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MSCs Contribute to the Conversion of Ly6Chigh Monocytes into Ly6Clow Subsets under AMI by Wenbin Lu, Genshan Ma, Zulong Sheng, Qingjie Wang, Lijuan Chen, Junhua Qi, Ronghui Shi, Jingjing Ji, Zhenjun Ji, Qiming Dai

“…Ly6Chigh/low monocytes were first cocultured with MSCs. C57BL/6CX3CR1-/- mice and C57BL/6 wild-type mice were then used to construct AMI models, and survival functions in the two groups were further compared. …”
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Susceptibility of different mice species to chemical induction of colorectal cancer by 1,2-dimethylhydrazine by Nourhan M. Abdelmaksoud, Ahmed I. Abulsoud, Tamer M. Abdelghany, Shereen Saeid Elshaer, Ahmed Samaha, Nadine W. Maurice, Sherine Maher Rizk, Mahmoud A. Senousy

“…Results Results revealed that C57BL/6 had a higher response to DMH compared to BALB/c. …”
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Contrasting Effects of Systemic Monocyte/Macrophage and CD4+ T Cell Depletion in a Reversible Ureteral Obstruction Mouse Model of Chronic Kidney Disease by Lee D. Chaves, Liby Mathew, Mohammed Shakaib, Anthony Chang, Richard J. Quigg, Tipu S. Puri

“…Using a reversible UUO model (rUUO), we have demonstrated that C57BL/6 mice are susceptible to development of CKD after obstruction-mediated kidney injury while BALB/c mice are resistant. …”
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Plateau hypoxia improves tumor immune microenvironment and inhibits subcutaneous tumor growth of colorectal cancer by ZHAO Sijie, WANG Meng, GAO Yuan

“…Colorectal tumor MC38 cells and colon adenocarcinoma CT26 cells were subcutaneously implanted into C57BL/6 mice and BALB/C mice， respectively to construct subcutaneous tumor-bearing mouse models. …”
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小檗碱对甲型流感病毒FM1株感染小鼠肺中RLH信号通路的影响

“…【方法】以50 μL流感病毒FM1株LD50滴鼻感染RIG-I?/?小鼠和正常野生型C57BL/6小鼠，建立小鼠流感模型，分别用小檗碱和奥司他韦治疗。观察小鼠的生存率以及肺组织炎症损伤状况；RT-PCR和Western-blot检测正常野生型C57BL/6小鼠RIG-I信号通路中RIG-I、NF-κB和MAVS的表达。 …”
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2 型固有淋巴细胞主导的小鼠呼吸道变应性炎症模型的建立 by 孟祥慈

“…【目的】应用野生型C57BL/6小鼠和T/B细胞缺陷的Rag1-/-小鼠建立以2型固有淋巴细胞（ILC2）为主导的小鼠呼吸道变应性炎症模型。…”
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Genetic variation in IL-4 activated tissue resident macrophages determines strain-specific synergistic responses to LPS epigenetically by Mingming Zhao, Dragana Jankovic, Verena M. Link, Camila Oliveira Silva Souza, Katherine M. Hornick, Oyebola Oyesola, Yasmine Belkaid, Justin Lack, Png Loke

“…We investigate IL-4 activation of male C57BL/6 and BALB/c strain specific in vivo tissue-resident macrophages (TRMs) from the peritoneal cavity. …”
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Determination of Fatty Acid Metabolism with Dynamic [C]Palmitate Positron Emission Tomography of Mouse Heart In Vivo by Yinlin Li, Tao Huang, Xinyue Zhang, Min Zhong, Natalie N. Walker, Jiang He, Stuart S. Berr, Susanna R. Keller, Bijoy K. Kundu

“…The MFAO thus measured in C57BL/6 mice was 375.03 ± 43.83 nmol/min/g. This compares well to the MFAO measured in perfused working C57BL/6 mouse hearts ex vivo of about 350 nmol/g/min and 400 nmol/min/g. …”
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Conducting and automating the water Morris maze test in SPF conditions by N. V. Khotskin, V. A. Kulikov, E. L. Zavyalov, D. V. Fursenko, A. V. Kulikov

“…With this installation, we were able to study the spatial ability to learn and spatial memory in mice of the C57BL/6 strain and in mice of the C57BL/6/ Kaiso strain developed on the C57BL/6 background, with the gene encoding the methyl-DNA binding Kaiso protein knocked-out. …”
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全不相合与全相合骨髓细胞在致敏模型的归巢与植入

“…【目的】 探讨全不相合与全相合供者骨髓细胞在致敏模型的归巢与植入情况【方法】 以异基因脾细胞输注致敏的BALB/c小鼠作为移植受者,致敏模型经8 Gy 60Co照射后分别经尾静脉移植1 × 107 C57BL/6或BALB/c供者的骨髓细胞予CFSE标记供者骨髓细胞,并分别在移植后不同时间点(212及48 h),通过病理切片及组织细胞悬液动态示踪供者细胞在致敏受者各组织的分布移植后记录各组的生存情况,每周监测造血重建与骨髓恢复情况【结果】 归巢实验表明C57BL/6骨髓细胞在致敏受者股骨的分布随时间推移先增加而后减少,在脾脏的分布随时间推移呈进行性减少BALB/c骨髓细胞在致敏模型股骨及脾脏的分布均随时间推移而增加接受C57BL/6骨髓细胞的致敏模型于移植第12 ~ 15天内全部死亡,血象及骨髓象呈进行性下降;而接受BALB/c骨髓细胞的能长期存活,血象及骨髓象能迅速恢复【结论】 全不相合的供者骨髓细胞在致敏模型中完全被排斥,而全相合供者的骨髓细胞能在致敏模型中能进行有效的归巢与植入…”
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