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The Redox System in C. elegans, a Phylogenetic Approach
Published 2012-01-01“…We use protein sequences from central redox systems in Homo sapiens, Drosophila melanogaster, and Saccharomyces cerevisiae to query Genbank for homologous proteins in C. elegans. We then use maximum likelihood phylogenetic analysis to compare protein families between C. elegans and the other organisms to facilitate future research into the genetics of redox biology.…”
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The role of lin-12 notch in C. elegans anchor cell proliferation
Published 2024-12-01Subjects: “…lin-12 notch, c. elegans…”
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Glia detect and transiently protect against dendrite substructure disruption in C. elegans
Published 2025-01-01“…We demonstrate that disruption of C. elegans sensory neuron dendrite cilia elicits acute glial responses, including increased accumulation of glia-derived extracellular matrix around cilia, changes in gene expression, and alteration of secreted protein repertoire. …”
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Gene regulatory patterning codes in early cell fate specification of the C. elegans embryo
Published 2024-01-01Subjects: Get full text
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Biophysical modeling and experimental analysis of the dynamics of C. elegans body-wall muscle cells.
Published 2025-01-01“…This study combines experimental techniques and mathematical modeling to investigate the dynamics of C. elegans body-wall muscle cells. Specifically, by conducting voltage clamp and mutant experiments, we identify key ion channels, particularly the L-type voltage-gated calcium channel (EGL-19) and potassium channels (SHK-1, SLO-2), which are crucial for generating action potentials. …”
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A higher order PUF complex is central to regulation of C. elegans germline stem cells
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Intergenerational transport of double-stranded RNA in C. elegans can limit heritable epigenetic changes
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SEM-2/SoxC regulates multiple aspects of C. elegans postembryonic mesoderm development.
Published 2025-01-01“…First, SEM-2 functions antagonistically with LET-381, the sole C. elegans FoxF/C forkhead transcription factor, to regulate dorsoventral patterning of the M lineage. …”
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Mutations of the Electron Transport Chain Affect Lifespan and ROS Levels in <i>C. elegans</i>
Published 2025-01-01“…This review underscores the translational relevance of ETC research in <i>C. elegans</i>, bridging fundamental biology and therapeutic innovation.…”
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High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models
Published 2025-01-01“…Here, we show that high-throughput imaging and quantitative phenotyping can be conducted systematically on a panel of C. elegans disease model strains. We used CRISPR genome-editing to create 25 worm models of human Mendelian diseases and phenotyped them using a single standardised assay. …”
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Correction: Gene regulatory patterning codes in early cell fate specification of the C. elegans embryo
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ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics.
Published 2016-09-01“…We report a new role for ATX-2, a C. elegans ortholog of Human Ataxin-2, in regulating centrosome size and MT dynamics. …”
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Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells.
Published 2024-12-01“…Here we use in situ live-cell imaging of C. elegans germline stem and progenitor cells (GSPCs) to ask how the signaling environment influences stem and progenitor cell mitosis in vivo. …”
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Machine learning-based analysis of microfluidic device immobilized C. elegans for automated developmental toxicity testing
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A distant TANGO1 family member promotes vitellogenin export from the ER in C. elegans
Published 2025-02-01“…Here, we report the C. elegans TNGL-1 as a mediator of vitellogenin export from the ER. …”
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Caenorhabditis elegans in the biological activity research of tea: From “little transparent” to “big star”
Published 2025-02-01Subjects: Get full text
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Spectral scanning and fluorescence lifetime imaging microscopy (FLIM) enable separation and characterization of C. elegans autofluorescence in the cuticle and gut
Published 2024-12-01Subjects: “…c. elegans…”
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