Showing 1 - 20 results of 78 for search '"C. elegans"', query time: 0.05s Refine Results
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    The Redox System in C. elegans, a Phylogenetic Approach by Andrew D. Johnston, Paul R. Ebert

    Published 2012-01-01
    “…We use protein sequences from central redox systems in Homo sapiens, Drosophila melanogaster, and Saccharomyces cerevisiae to query Genbank for homologous proteins in C. elegans. We then use maximum likelihood phylogenetic analysis to compare protein families between C. elegans and the other organisms to facilitate future research into the genetics of redox biology.…”
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    The role of lin-12 notch in C. elegans anchor cell proliferation by Alex Hajnal, Ting Deng, Evelyn Lattmann

    Published 2024-12-01
    Subjects: “…lin-12 notch, c. elegans…”
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    Glia detect and transiently protect against dendrite substructure disruption in C. elegans by Katherine C. Varandas, Brianna M. Hodges, Lauren Lubeck, Amelia Farinas, Yupu Liang, Yun Lu, Shai Shaham

    Published 2025-01-01
    “…We demonstrate that disruption of C. elegans sensory neuron dendrite cilia elicits acute glial responses, including increased accumulation of glia-derived extracellular matrix around cilia, changes in gene expression, and alteration of secreted protein repertoire. …”
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    Biophysical modeling and experimental analysis of the dynamics of C. elegans body-wall muscle cells. by Xuexing Du, Jennifer Crodelle, Victor James Barranca, Songting Li, Yunzhu Shi, Shangbang Gao, Douglas Zhou

    Published 2025-01-01
    “…This study combines experimental techniques and mathematical modeling to investigate the dynamics of C. elegans body-wall muscle cells. Specifically, by conducting voltage clamp and mutant experiments, we identify key ion channels, particularly the L-type voltage-gated calcium channel (EGL-19) and potassium channels (SHK-1, SLO-2), which are crucial for generating action potentials. …”
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    SEM-2/SoxC regulates multiple aspects of C. elegans postembryonic mesoderm development. by Marissa Baccas, Vanathi Ganesan, Amy Leung, Lucas R Pineiro, Alexandra N McKillop, Jun Liu

    Published 2025-01-01
    “…First, SEM-2 functions antagonistically with LET-381, the sole C. elegans FoxF/C forkhead transcription factor, to regulate dorsoventral patterning of the M lineage. …”
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    Mutations of the Electron Transport Chain Affect Lifespan and ROS Levels in <i>C. elegans</i> by Fanni Ősz, Aamir Nazir, Krisztina Takács-Vellai, Zsolt Farkas

    Published 2025-01-01
    “…This review underscores the translational relevance of ETC research in <i>C. elegans</i>, bridging fundamental biology and therapeutic innovation.…”
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    High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models by Thomas J O'Brien, Ida L Barlow, Luigi Feriani, André EX Brown

    Published 2025-01-01
    “…Here, we show that high-throughput imaging and quantitative phenotyping can be conducted systematically on a panel of C. elegans disease model strains. We used CRISPR genome-editing to create 25 worm models of human Mendelian diseases and phenotyped them using a single standardised assay. …”
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    ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics. by Michael D Stubenvoll, Jeffrey C Medley, Miranda Irwin, Mi Hye Song

    Published 2016-09-01
    “…We report a new role for ATX-2, a C. elegans ortholog of Human Ataxin-2, in regulating centrosome size and MT dynamics. …”
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    Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells. by Eric Cheng, Ran Lu, Abigail R Gerhold

    Published 2024-12-01
    “…Here we use in situ live-cell imaging of C. elegans germline stem and progenitor cells (GSPCs) to ask how the signaling environment influences stem and progenitor cell mitosis in vivo. …”
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    A distant TANGO1 family member promotes vitellogenin export from the ER in C. elegans by Jimmy H. Mo, Chao Zhai, Kwangsek Jung, Yan Li, Yonghong Yan, Meng-Qiu Dong, Ho Yi Mak

    Published 2025-02-01
    “…Here, we report the C. elegans TNGL-1 as a mediator of vitellogenin export from the ER. …”
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