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197221
Manganese-based immunotherapy synergized with novel supramolecular hydrogel: Advancing localized immune activation strategies in squamous cell carcinoma
Published 2025-02-01“…Firstly, we used a tumor-immune cell co-culture system to demonstrate that Mn2+ enhances immune cytotoxicity in HNSCC via cGAS-STING activation. Subsequently, we used an orthotopic transplant tumor model to validate that Mn-IT exerts antitumor effects and immune activation in HNSCC. …”
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197225
بررسی اثر دو گونه جلبک دریایی قرمز بر شاخصهای رشدی، فیزیولوژیکی و عملکرد میوه خیار آب پران تحت تاثیر روش عصارهگیری...
Published 2022-09-01“…تیمارهای آزمایش شامل پنج روش استخراج (ME: عصاره استخراجی مایکروویو با حلال آبی، OE: عصاره استخراجی اتوکلاو با حلال آبی، BE: عصاره استخراج شده با روش جوشاندن با آب مقطر، NE: عصاره استخراج شده با ازت مایع، EE: عصاره خیسانده شده در اتانول) و یک نمونه شاهد (C: (محلولپاشی با آب مقطر) بود. در طول دور رشد تعداد برگ، تعداد گل نر و ماده و تعداد میوهها اندازهگیری شد. …”
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Basic Molecular Biology, Metabolic and Immunological Mechanisms of Fecal Microbiota Transplantation
Published 2024-12-01Get full text
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Defining indicators for disease burden, health outcomes, policies and barriers and facilitators to health services for migrant populations in the Middle East and North African regi...
Published 2024-07-01“…This protocol describes a suite of seven systematic reviews that aim to identify, appraise and synthesise the available evidence on the burden and health outcomes, policies and access (barriers and facilitators) related to these mobile populations in the region.Methods Seven systematic reviews will cover three questions to explore the: (1) burden and health outcomes, (2) policies and (3) healthcare barriers and facilitators for the following seven disease areas in migrants in the MENA region: tuberculosis, HIV and hepatitis B and C, malaria and neglected tropical diseases, diabetes, mental health, maternal and neonatal health, and vaccine-preventable diseases. …”
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واکاوی عملکرد ارقام جدید گندم نان بر اساس شاخصهای زراعی- اقلیمی تحت تاریخ کاشتهای مختلف در گنبد
Published 2021-03-01Get full text
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Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation
Published 2025-01-01“…Abstract Apoptotic protease activating factor 1 (Apaf-1) was traditionally defined as a scaffold protein in mammalian cells for assembling a caspase activation platform known as the ‘apoptosome’ after its binding to cytochrome c. Although Apaf-1 structurally resembles animal NOD-like receptor (NLR) and plant resistance (R) proteins, whether it is directly involved in innate immunity is still largely unknown. …”
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Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics f...
Published 2025-01-01“…UC-MSC-sEV characterization under non-cGMP conditions showed consistent miRNA and protein profiles, suggesting their potential for standardized manufacturing. …”
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