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    An efficient measure for the isolation of chenodeoxycholic acid from chicken biles using enzyme-assisted extraction and macroporous resins refining by Biao Yang, Fangyun Lu, Pengpeng Li, Jingjing Ma, Jing Yang, Xinxiao Zhang, Mei Cheng, Wenjing Yu, Yao Chai, Ye Zou, Weimin Xu, Daoying Wang

    Published 2025-01-01
    “…For the assisted extraction of CDCA, the active bile salt hydrolase (BSH) from Bifidobacterium was heterologously expressed and applied, its activities on GCDCA and TCDCA were 4.96 ± 0.32 U/mg and 3.07 ± 0.031 U/mg and optimal catalytic conditions for the extraction of CDCA were determined as 0.04 g/g of the enzyme dosage, pH 5.0 and 38 °C. Through validation of the conditions, the yield of CDCA was up to 5.32 %, which was equivalent to that by saponification method. …”
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  5. 195945

    Dual‐Enhanced SERS Satellite Immuno‐Nanocomplex for Multiple PSA‐Mediated PHI Assay Toward Clinical Prostate Cancer Screening by Dong Chen, Yilin Ma, Annan Yang, Liping Hu, Hanlin Zhou, Jun Xu, Shanze Chen, Dingmeng Nie, Weifeng Feng, Huaihong Cai, Yanguang Cong, Jiang Pi, Lang Rao, Xueqin Huang, Pinghua Sun, Haibo Zhou

    Published 2025-02-01
    “…Herein, this study reports a double‐SERS satellite immunoassay, made of an Au–Ag dealloyed intra‐nanogap nanoflower (Au–Ag DINF) with strong SERS signals and Au magnetic nanoparticles (AuMNPs) with magnetic capture and SERS amplification, for sensing multiple PSA (free PSA (fPSA), complexed PSA (cPSA) and [‐2]proPSA (p2PSA)) toward potential PCa screening. …”
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