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    Synthesis and Anti-Cancer Activity In Vitro of Synephrine Derivatives by Ekaterina M. Zhidkova, Evgeniya S. Oleynik, Ekaterina A. Mikhina, Daria V. Stepanycheva, Diana D. Grigoreva, Lyubov E. Grebenkina, Kirill V. Gordeev, Ekaterina D. Savina, Andrey V. Matveev, Marianna G. Yakubovskaya, Ekaterina A. Lesovaya

    Published 2024-12-01
    “…We synthesized 26 novel compounds from the class of synephrine derivatives and characterized them by HRMS, and <sup>1</sup>H and <sup>13</sup>C NMR. We evaluated <i>in vitro</i> anti-cancer effects in leukemia K562 and lymphoma Granta cells using the MTT assay and studied their potential affinity for the glucocorticoid receptor (GR) <i>in silico</i> using the molecular docking approach. …”
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