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    Cyclopiazonic acid suppresses the function of Leydig cells in prepubertal male rats by disrupting mitofusin 1-mediated mitochondrial function by Hang Lin, Ming Su, He Zhu, Yang Yu, Jianmin Sang, Yiyan Wang, Qiqi Zhu, Yang Zhu, Xiaoheng Li, Xingwang Li, Ren-Shan Ge, Huitao Li

    Published 2025-01-01
    “…In vitro experiments corroborated these observations, demonstrating that CPA induced mitochondrial fragmentation by downregulating SIRT1, PGC1-α, MFN1, and OPA1, increase reactive oxygen species, and inhibit testosterone synthesis in R2C cells. The administration of leflunomide was shown to mitigate the detrimental effects of CPA on PLCs. …”
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  8. 194928
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    Asymmetries and Circumstellar Interaction in the Type II SN 2024bch by Jennifer E. Andrews, Manisha Shrestha, K. Azalee Bostroem, Yize Dong, Jeniveve Pearson, M. M. Fausnaugh, David J. Sand, S. Valenti, Aravind P. Ravi, Emily Hoang, Griffin Hosseinzadeh, Ilya Ilyin, Daryl Janzen, M. J. Lundquist, Nicolás Meza, Nathan Smith, Saurabh W. Jha, Moira Andrews, Joseph Farah, Estefania Padilla Gonzalez, D. Andrew Howell, Curtis McCully, Megan Newsome, Craig Pellegrino, Giacomo Terreran, Patrick Wiggins, Brian Hsu, Collin T. Christy, Noah Franz, Xiaofeng Wang, Jialian Liu, Liyang Chen

    Published 2025-01-01
    “…Optical spectra from 2.8 days after the estimated explosion reveal narrow lines of H  i , He  ii , C  iv , and N  iv that disappear by day 6. High-cadence photometry from the ground and Transiting Exoplanet Survey Satellite show that the SN brightened quickly and reached a peak M _V  ~ −17.8 mag within a week of explosion, and late-time photometry suggests a ^56 Ni mass of 0.050 M _⊙ . …”
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