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    Single-cell RNA sequencing of the spleen reveals differences in Salmonella typhimurium infection mechanisms between different chicken breeds by Qi Zhang, Qiao Wang, Jumei Zheng, Jin Zhang, Gaomeng Zhang, Fan Ying, Dawei Liu, Jie Wen, Qinghe Li, Guiping Zhao

    Published 2025-02-01
    “…In addition, we found complex macrophage phenotypes during bacterial infection, with a tendency in macrophages from pro-inflammatory phenotypes (Mac-IL1B) to anti-inflammatory phenotypes (Mac-C1QC/Mac-MARCO). This study represents the first single-cell transcriptomic analysis of chicken spleen and compares the immune responses of Beijing-You and Cobb after bacterial infection. …”
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