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IL-17 triggers PD-L1 gene transcription in NSCLC cells via TRIM31-dependent MEF2C K63-linked polyubiquitination
Published 2025-01-01Subjects: Get full text
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Exceptional Response of Metastatic Chromophobe Renal Cell Carcinoma to Vascular Endothelial Growth Factor (VEGF) Inhibitors: Should Increased VEGF-C Expression Be Used to Guide Treatment?
Published 2019-01-01“…Tumor gene expression profiling using Affymetrix HG-U133 Plus 2.0 GeneChip platform demonstrated significantly elevated VEGF-C expression compared to normal renal tissue n=12 and other types RCC n=158. …”
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Comparative study on the weight loss and lipid metabolism by tea polyphenols in diet induced obese C57BL/6J pseudo germ free and conventionalized mice
Published 2022-05-01“…After the dietary administration of TP, body weight, perirenal fat and epididymal fat, liver weight, glucose (GLU) level, total chloestrol (TC level), high density lipoprotein-cholesterol (HDL-C) level significantly lowered in PGF mice as compared to CVZ mice group. …”
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Optimization of Development Strategies and Injection-Production Parameters in a Fractured-Vuggy Carbonate Reservoir by Considering the Effect of Karst Patterns: Taking C Oilfield in the Tarim Basin as an Example
Published 2025-01-01“…By taking a typical fractured-vuggy reservoir in C oilfield in Tarim Basin, China as an example, the development dynamic characteristics of eight typical fractured-vuggy units in three different karst patterns are analyzed, and based on the newly proposed numerical simulation method of fluid vertical equilibrium, the residual oil reservoir distribution in different karst pattern fractured-vuggy units are studied, and the effects of fracture-vuggy karst patterns on the development characteristics, on the remaining oil morphology pattern, on the development strategies, and on the injection-production parameters are explored. …”
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Dual-Mechanism Study of Metal-Free g-C<sub>3</sub>N<sub>4</sub> Catalysts for Advanced Oxidation Under Non-Photocatalytic Conditions
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The crystal structure of 2,5,5-triphenyl-3,5-dihydro-4H-imidazol-4-one, C21H16N2O
Published 2022-08-01“…C21H16N2O, monoclinic, P21/c (no. 14), a = 13.8987(3) Å, b = 15.0321(5) Å, c = 8.1727(2) Å, β = 99.337(2)°, V = 1684.87(8) Å3, Z = 4, Rgt(F) = 0.0411, wRref(F2) = 0.1137, T = 293(2) K.…”
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HFE-Related Hemochromatosis: The Haptoglobin 2-2 Type Has a Significant but Limited Influence on Phenotypic Expression of the Predominant p.C282Y Homozygous Genotype
Published 2009-01-01“…Phenotypic expression of the common p.C282Y/p.C282Y HFE-related hemochromatosis genotype is heterogeneous and depends on a complex interplay of genetic and non-genetic factors. …”
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Selective ATP-Binding Cassette Subfamily C Gene Expression and Proinflammatory Mediators Released by BEAS-2B after PM2.5, Budesonide, and Cotreated Exposures
Published 2017-01-01“…ATP-binding cassette subfamily C (ABCC) genes code for phase III metabolism proteins that translocate xenobiotic (e.g., particulate matter 2.5 (PM2.5)) and drug metabolites outside the cells. …”
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Designing a Long Acting Erythropoietin by Fusing Three Carboxyl-Terminal Peptides of Human Chorionic Gonadotropin β Subunit to the N-Terminal and C-Terminal Coding Sequence
Published 2011-01-01“…A new analog of EPO was designed by fusing one and two CTPs to the N-terminal and C-terminal ends of EPO (EPO-(CTP)3), respectively. …”
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Evaluation of the a-amylase enzyme, Carbohydrate Antigen CA-15.3 ( C.A 15.3),and some biochemical variables in the blood serum of breast cancer patients
Published 2025-01-01“… Evaluation of the amylase enzyme and some biochemical variables in the serum of breast cancer patients for all stages of the disease in patients compared to healthy women. The tumor marker (C.A 15.3) is one of the most reliable markers for monitoring metastatic breast cancer. …”
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Protein Kinase Cε, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells
Published 2013-01-01“…To find clues about the mechanism by which kinase C epsilon (PKCε) may impart susceptibility to ultraviolet radiation (UVR)-induced development of cutaneous squamous cell carcinomas (SCC), we compared PKCε transgenic (TG) mice and their wild-type (WT) littermates for (1) the effects of UVR exposures on percent of putative hair follicle stem cells (HSCs) and (2) HSCs proliferation. …”
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Higher Levels of High-Sensitivity C-Reactive Protein Is Positively Associated with the Incidence of Hyperuricemia in Chinese Population: A Report from the China Health and Retirement Longitudinal Study
Published 2020-01-01“…The aim of the present cohort study was to explore the longitudinal association between high-sensitivity C-reactive protein (CRP) and hyperuricemia in Chinese population. …”
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