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Single-Institution Experience With Nononcologic Total Femoral Replacement
Published 2025-02-01Get full text
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The mechanism of discriminative aminoacylation by isoleucyl-tRNA synthetase based on wobble nucleotide recognition
Published 2024-12-01“…ScIleRS utilizes a eukaryotic/archaeal-specific arginine as the H-bond donor to recognize the common carbonyl group (H-bond acceptor) of various N34s of tRNAIle, which induces mutual structural adaptations between ScIleRS and tRNAIle to achieve a preferable editing state. C34 of unmodified tRNAIle(CAU) (behaves like tRNAMet) lacks a relevant H-bond acceptor, which disrupts key H-bonding interactions and structural adaptations and suspends the ScIleRS·tRNAIle(CAU) complex in an initial non-reactive state. …”
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The Effect of Prebiotics, Alone or as Part of Synbiotics, on Cardiometabolic Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized...
Published 2025-01-01“…Results showed high-quality evidence supporting prebiotics’ effects, alone or as part of synbiotics, in reducing body-mass index [<i>n</i> = 853; weighted-mean difference (WMD): −0.510, 95%CI: −0.669, −0.351 kg/m<sup>2</sup>] and diastolic blood pressure (WMD: −2.218, 95%CI: −4.425, −0.010 mmHg), moderate-quality evidence for weight, waist-to-hip ratio, and triglycerides improvements, and low or very-low-quality evidence for waist circumference (WC), fat mass, fasting plasma glucose, fasting insulin, low-density lipoprotein (LDL), total cholesterol (TC), high sensitive-C reactive protein, total testosterone, follicle-stimulating hormone and free androgen index improvements. …”
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An indole alkaloid from a tribal folklore inhibits immediate early event in HSV-2 infected cells with therapeutic efficacy in vaginally infected mice.
Published 2013-01-01“…The cytotoxicity (CC50), effective concentrations (EC50) and the mode of action of HM was determined by MTT, plaque reduction, time-of-addition, immunofluorescence (IFA), Western blot, qRT-PCR, EMSA, supershift and co-immunoprecipitation assays; while the in vivo toxicity and efficacy was evaluated in BALB/c mice. The results revealed that HM possesses significant anti-HSV-2 activity with EC50 of 1.1-2.8 µg/ml, and selectivity index of >20. …”
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A Novel Model for Predicting the Well Production in High-Sulfur-Content Gas Reservoirs
Published 2021-01-01Get full text
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Pathogenetic Substantiation of the Therapeutic Impact on Microbiota in Irritable Bowel Syndrome
Published 2019-09-01Get full text
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The role of light in regulating plant growth, development and sugar metabolism: a review
Published 2025-01-01Get full text
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Intense Red Upconversion Emission and Shape Controlled Synthesis of Gd2O3:Yb/Er Nanocrystals
Published 2013-01-01Get full text
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Caracterización clínico-epidemiológica de la enfermedad de Paget de la mama. Estudio de 37 años
Published 2017-04-01Get full text
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Producción científica en América Latina y el Caribe en el período 1996-2019
Published 2020-08-01Get full text
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