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  1. 262401

    3-Acetyldeoxynivalenol induces pyroptosis in leydig cells via METTL3-mediated N6-methyladenosine modification of NLRP3 by Yangyun Wang, Chaoliang Shi, Wei Jiao, Xiaoxiang Wan

    Published 2025-01-01
    “…Additionally, we identified that METTL3 also methylates and stabilizes c-MyB mRNA, which subsequently binds to the promoter region of NLRP3, thereby enhancing its transcription. …”
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    Two chromatographic methods for analyzing paracetamol in spiked human plasma with its toxic metabolite, N-acetyl parabenzoquinone imine and its antidote, N-acetyl-l-cysteine by Omar M El-Abassy, Michael Gamal Fawzy, Ebraam B. Kamel

    Published 2025-02-01
    “…The stationary phase used in the approach was a C18 column. Analytes quantification was established utilizing a UV detector operating at a wavelength of 254 nm. …”
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    Social support from different sources and its relationship with stress in spaceflight analog environments by Suzanne T. Bell, Steven R. Anderson, Peter G. Roma, Lauren Blackwell Landon, Sheena I. Dev

    Published 2025-01-01
    “…Our results are important as they: (a) empirically document the decline in perceived social support over time in extended isolation; (b) provide evidence for the critical importance of the role of fellow crewmembers in being able to provide social support in conditions of extended isolation and communication delay; and (c) underscore the need to more fully understand the dynamics between the crew and external sources of social support (public, organization, family/friends/colleagues) as well as how those relationships may be best supported for individuals who live and work in long-term isolation and confinement.…”
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  20. 262420