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    Risk of first venous thrombosis by comparing different thrombin generation assay conditions: results from the MEGA case-control study. by Kristien Winckers, Eugenia Biguzzi, Stella Thomassen, Alexandra Heinzmann, Frits R. Rosendaal, Tilman Mathias Hackeng, Astrid van Hylckama Vlieg

    “…Methods: Basal TG at low tissue factor (TF) concentration and high TF concentration in the presence and absence of activated protein C (APC) were measured in plasma samples from 2,081 patients with first VTE and 2,908 healthy controls from the MEGA study. …”
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    Joint Adaptive OFDM and Reinforcement Learning Design for Autonomous Vehicles: Leveraging Age of Updates by Mamady Delamou, Ahmed Naeem, Huseyin Arslan, El Mehdi Amhoud

    Published 2025-01-01
    “…The system is validated using advantage actor-critic (A2C) and proximal policy optimization (PPO). Furthermore, we compare our solution with the existing design and demonstrate its superior performance by computer simulations.…”
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    Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1 by Anamika Biswas, Samina Arshid, Kristian Kølby Kristensen, Thomas J.D. Jørgensen, Michael Ploug

    Published 2025-02-01
    “…Acidic residues at positions 19–30 in GPIHBP1 mapped to Lys445, Lys441, Lys414, and Lys407 close to the interface between the C- and N-terminal domains in LPL. Modeling this interface revealed widespread polyelectrolyte interactions spanning both LPL domains, which explains why the acidic tail stabilizes LPL activity and protein conformation. …”
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