Galactin-8 DNA methylation mediates macrophage autophagy through the MAPK/mTOR pathway to alleviate atherosclerosis by Bing Xia, Yan-lin Lu, Jin Peng, Jing-wei Liang, Fang-qin Li, Jiu-yang Ding, Chang-wu Wan, Cui-yun Le, Jia-lin Dai, Jie-Wang, Bing Guo, Jiang Huang

“…Following DNMT1 inhibition, the DC05 group displayed a significant decrease in methylation across all six CpG sites compared to the C57 and AS groups. Conversely, the UO126 group exhibited increased methylation at the first three CpG loci relative to the AS group. …”
Get full text

Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome by Cristina Alonso, Alicia García-Culebras, Valentina Satta, Inés Hernández-Fisac, Álvaro Sierra, José A. Guimaré, Ignacio Lizasoain, Javier Fernández-Ruiz, Onintza Sagredo

Get full text

Bioinformatic characterization of STING expression in hematological malignancies reveals association with prognosis and anti-tumor immunity by Xiang-mei Wen, Xiang-mei Wen, Xiang-mei Wen, Zi-jun Xu, Zi-jun Xu, Zi-jun Xu, Ji-chun Ma, Ji-chun Ma, Ji-chun Ma, Min-jie Zhang, Min-jie Zhang, Min-jie Zhang, Ye Jin, Ye Jin, Jiang Lin, Jiang Lin, Jiang Lin, Jun Qian, Jun Qian, Yuan-yuan Fang, Yuan-yuan Fang, Yuan-yuan Fang, Shu-yu Luo, Shu-yu Luo, Shu-yu Luo, Zhen-wei Mao

“…IntroductionStimulator of interferon response cGAMP interactor (STING) is essential for both innate and adaptive immunity. …”
Get full text

A Predictive Model for Pulmonary Aspergillosis in ICU Patients: A Multicenter Retrospective Cohort Study by Li Y, Ren X, Wang Q, Shen S, Li Y, Qian X, Tang Y, Jia J, Zhang H, Ding J, Song Y, Zhang S, Wang S, Xu Y, Jiang Y, He X, Dai M, Zhong L, Xiong Y, Pan Y, Wang M, Shao H, Cai H, Huang L, Wang H

Get full text

بررسی تنوع ژنوتیپ‌های گندم نان بر اساس عملکرد و صفات مرتبط با عملکرد تحت شرایط تنش بیماری زنگ زرد (Puccinia striiformis)... by امین افضلی فر, فرزاد افشاری, لیلا فهمیده, صالحه گنجعلی, محمدرضا بی‌همتا, هادی علی پور

Get full text

Editorial by Lindsay B. Flynn

Get full text

Study on the improvement of behavior and pain and the mechanism of Yangpafang in subacute Parkinson's disease model mice by SHI Ying, MEI Shan‐shan, WANG Yuan‐ling, XIA A‐long, WANG Xiao‐wei, LI Jun

“…Methods Total 42 specific pathogen⁃free (SPF) C57BL/6J mice were randomly divided into control group, model group, Yangpafang low⁃ dose group [13.50 g/(kg·d)], medium ⁃dose group [40.50 g/(kg·d)] and high⁃dose group [121.50 g/(kg·d)], levodopa and benserazide group (7 mice in each group). …”
Get full text

A PCR-independent, annealing-free cloning method for the insertion of short DNA fragments by Li Linbo, Yan Jin, Qi Yuan, Xiang Zhenglong, Jiang Na, Yuan Tongkang, Wang Zhenyi, Wang Yuan, Zhan Huaizhe, Liu Shiyi, Zhao Li, Xu Jing, Lei Xiaowei, Liu Yuxuan, Wang Gui, Xie Jiayang, Guo Zhenming, Cai Chunhai, Bian Shan

Get full text

Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb) by Hiroaki Tanaka, Yasuhiro Tanaka, Yoichi Aoki, Masayuki Endo, Tomoaki Ikeda, Shintaro Maki, Masafumi Nii, Kayo Tanaka, Satoshi Tamaru, Toru Ogura, Yuki Nishimura, Tomomi Kotani, Akihiko Sekizawa, Masahiko Nakata, Koji Nakamura, Kenji Nagao, Ichiro Yasuhi, Hiroshi Kawamura, Sho Takakura, Mayumi Kotera, Takafumi Ushida, Norihiko Kikuchi, Tadatsugu Kinjo, Mayumi Takano, Sachie Suga, Michi Kasai, Osamu Yasui, Yuka Maegawa, Shigeru Aoki, Yoshio Yoshida

“…To establish further evidence for the efficacy of tadalafil in this setting, we planned a multicentre, randomised, placebo-controlled, double-blind trial.Methods and analysis This trial will be conducted in 180 fetuses with fetal growth restriction enrolled from medical centres in Japan; their mothers will be randomised into three groups: arm A, receiving two times per day placebo; arm B, receiving one time per day 20 mg tadalafil and one time per day placebo and arm C, receiving 20 mg two times per day tadalafil. …”
Get full text

Comprehensive prognosis assessment of cardiovascular magnetic resonance parametric mapping in light chain amyloidosis by Xiao Li, Yubo Guo, Kaini Shen, Sisi Huang, Yajuan Gao, Lu Lin, Jian Wang, Jian Cao, Xinxin Cao, Zhengyu Jin, Zhuoli Zhang, Akos Varga-Szemes, U. Joseph Schoepf, Jian Li, Yining Wang

Get full text

Genetic characteristics involving the PD-1/PD-L1/L2 and CD73/A2aR axes and the immunosuppressive microenvironment in DLBCL by Tingting Zhang, Zhenzhen Zhang, Xiubao Ren, Jin He, Zhengzi Qian, Bin Meng, Lei Jiao, Hengqi Liu, Lanfang Li, Lihua Qiu, Shiyong Zhou, Wenchen Gong, Huilai Zhang, Xianhuo Wang

Get full text

Elevated Bile Acids Induce Circadian Rhythm Sleep Disorders in Chronic Liver DiseasesSummary by Lan Zhou, Min Yan, Qin Luo, Wen Qiu, Yu-Ru Guo, Xiao-Qing Guo, Hong-Bin Yu, Jing-Ru Huo, Yan-Lin Feng, De-Ping Wang, Teng Sun, Kai-Fang Wang, Jian-Yun Shi, Xuan Shang, Mei-Na Wu, Lin Wang, Ji-Min Cao

Get full text

بررسی تنوع ژنتیکی برخی ژنوتیپ‌های لیمو اسیدی (Citrus aurantifolia Swingle) ایران بر پایه نشانگر AFLP by شاهین جهانگیرزاده خیاوی, یوسف حمیداوغلی, بهروز گلعین, عاطفه صبوری

“…دامنه تشابه بدست آمده توسط ضریب تشابه جاکارد بین 24/0 تا 96/0 بود که کمترین میزان بین لیمو شیرین (C. limetta) و ژنوتیپ D8 از داراب و حداکثر بین دو ژنوتیپ منطقه میناب (M4-2 و M4-2) مشاهده شد. …”
Get full text

AKRASIJA IR SUBJEKTAS EGONOMIKOJE by Zenonas Norkus

“…On the (2), egonomic fragmentation of the "monolithic self" is considered as the application of explanatory strategy called by Daniel C. Dennett "homuncular functionalism". Like the "homuncular" facon de parler in the cognitive science, egonomic talk on "multiple self" cannot be ontologized or reified. …”
Get full text

Pre-operative DNA methylation marks as predictors of weight loss outcomes after sleeve gastrectomy by Guillermo Paz-López, Teresa M. Linares-Pineda, Andrés González-Jiménez, Raquel Sancho-Marín, Luis Ocaña-Wilhelmi, Francisco J. Tinahones, Sonsoles Morcillo, Carolina Gutiérrez-Repiso

Get full text

İstanbul Tavrı Kur’ân-I Kerîm Tilâvetinde Kerim Öztürk’ün Kırâati Çerçevesinde Fatiha Sûresi; Makam Analizleri ve Notasyon by Esra Yılmaz

Get full text

Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis by Ruomei Cheng, Xiaopeng Tang, Qiyu Zhao, Yuming Wang, Wenlin Chen, Gan Wang, Chenxi Wang, James Mwangi, Qiumin Lu, Dawit Adisu Tadese, Xudong Zhao, Caiwen Ou, Ren Lai

Get full text

A Path to the Stars: The Evolution of the Species by Fabrizio Vitali, Guido Chincarini, Mario Zannoni, Stefano Covino, Emilio Molinari, Stefano Benetti, Carlotta Bonoli, Favio Bortoletto, Enrico Cascone, Rosario Cosentino, Francesco D'Alessio, Paolo D'Avanzo, Vincenzo De Caprio, Massimo Della Valle, Alberto Fernandez-Soto, Dino Fugazza, Enrico Giro, Demetrio Magrin, Giuseppe Malaspina, Lech Mankiewicz, Raffaella Margutti, Ruben Mazzoleni, Luciano Nicastro, Alberto Riva, Marco Riva, Ruben Salvaterra, Paolo Spanò, Monica Sperandio, Mauro Stefanon, Gino Tosti, Vincenzo Testa

Get full text

A qualitative study of symptoms and psychological experience of patients with delayed resolution after microvascular decompression for hemifacial spasm (面肌痉挛行微血管减压术后延迟治愈患者症状体验和心理感受... by JING Dan (井丹), LYU Yan (吕燕), XU Zai (徐再)

Get full text

Sistemas Fisiográficos del Área Natural Protegida "Valle Cretácico"; Provincia de Río Negro by Nora Romina Solorza, Marcos Damián Mare

Get full text