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  1. 205061
  2. 205062
  3. 205063

    Cross-cultural adaptation of the simple Chinese version of the medication adherence reasons scale in patients undergoing adjuvant endocrine therapy for breast cancer by Lei Xu, Ping Li, Yan Hu, Weijie Xing, Jiajia Qiu, Xiaoju Zhang, Lingying Jia, Feng Jing, Ye Liu, Lili Li, Chunyang Lu

    Published 2025-01-01
    “…Inclusion criteria were: (a) female, (b) aged 18 years or older, (c) diagnosed with Stage I to III BrCa, (d) completed primary treatment for hormone receptor-positive BrCa and had been on AET for more than six months but less than five years, (e) proficient in Mandarin, and (f) provided informed consent. …”
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  4. 205064
  5. 205065
  6. 205066
  7. 205067

    CRISPR-Cas9-based one-step multiplexed genome editing through optimizing guide RNA processing strategies in Pichia pastoris by Kaidi Chen, Gulikezi Maimaitirexiati, Qiannan Zhang, Yi Li, Xiangjian Liu, Hongting Tang, Xiang Gao, Bo Wang, Tao Yu, Shuyuan Guo

    Published 2025-06-01
    “…The system will contribute to the application of P. pastoris as an attractive cell factory for multiplexed compound biosynthesis and will serve as a valuable tool for enhancing one-carbon (C1) bio-utilization.…”
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  8. 205068

    Chromosome-level reference genome and annotation of the Arctic fish Anisarchus medius by Ruoyu Liu, Ziyu Meng, Yinan Mu, Ran Zhang, Hanhui Ma, Jingjing Hu, Yanan Wang, Yuxin Shi, Yanan Li, Chaofeng Wang, Weini Zhang, Longshan Lin, Ping Zheng, Xinhua Chen

    Published 2025-01-01
    “…Hi-C mapping yielded 23 chromosomes, with a successful mapping rate of 90.53% and a Scaffold N50 of 30.20 Mb. …”
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  9. 205069

    Pharmacokinetic Analysis of an Isoniazid Suspension Among Spanish Children Under 6 Years of Age by Antoni Noguera-Julian, Emma Wilhelmi, Maria Cussó, Rob Aarnoutse, Angela Colbers, Loreto Martorell, Maria Goretti López-Ramos, Joan Vinent, Rosa Farré, Dolors Soy, Sílvia Simó-Nebot, Clàudia Fortuny

    Published 2025-01-01
    “…Significant differences in C<sub>max</sub> (<i>p</i> = 0.030) and AUC<sub>0–24h</sub> (<i>p</i> = 0.011) values were observed based on acetylator status. …”
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  10. 205070

    HDAC and MEK inhibition synergistically suppresses HOXC6 and enhances PD-1 blockade efficacy in BRAFV600E-mutant microsatellite stable colorectal cancer by Xin Li, Peng Yang, Jin Gu, Nan Chen, Dengbo Ji, Jinhong Xia, Jinying Jia, Zhuang Sun, Mengyuan Shi, Hanyang Wang, Zhaoya Gao

    Published 2025-01-01
    “…Moreover, the combination therapy demonstrated the ability to enhance antitumor immunity by synergistically upregulating the expression of immune activation-related genes, activating the cyclic guanosine monophosphate–adenosine monophosphate synthase/stimulator of interferon genes (cGAS/STING) pathway, and diminishing the tumor cells’ DNA mismatch repair capacity. …”
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  11. 205071
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  13. 205073
  14. 205074
  15. 205075
  16. 205076
  17. 205077

    Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive B... by Ming Zhai, Peipei Luan, Yefei Shi, Bo Li, Jianhua Kang, Fan Hu, Mingjie Li, Lei Du, Donglei Zhou, Weixia Jian, Wenhui Peng

    Published 2021-01-01
    “…In protein-protein interaction network, we identified CSF1R, C1QC, and TYROBP as hub genes. GSEA analysis suggested high expression of the three hub genes was correlated with immune cells functional pathway’s activation. …”
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  18. 205078

    Profil Pasien Pneumonia Komunitas di Bagian Anak RSUP DR. M. Djamil Padang Sumatera Barat by Osharinanda Monita, Finny Fitry Yani, Yuniar Lestari

    Published 2015-01-01
    “…Keluhan utama anak dengan pneumonia yaitu sesak napas 97,8% dan gejala klinis yang ditemukan yaitu demam 92,7% dengan suhu rata-rata 37.6 C, batuk 92,1%, takipneu rata-rata laju napas 66 kali/menit pada kelompok usia &lt; 2bulan, takikardi rata-rata denyut nadi 124 kali/menit pada kelompok usia &gt;48-72 bulan, disertai nafas cuping hidung 92,7%, retraksi dinding dada 86%, ronkhi 91,6% dan wheezing 14,6%. …”
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  19. 205079
  20. 205080

    CircOMA1调控多巴胺受体促进泌乳素瘤耐药性 by 张译尹, 吴娜, 李雪莉, 胡斌, 吴欣仪, 朱永红

    Published 2022-05-01
    “…结论circOMA1通过miR-145-5p/KBTBD7轴下调DRD2表达,降低泌乳素瘤对DAs敏感性,并且调控多巴胺受体表达激活cAMP通路促进泌乳素合成释放,从而促进泌乳素瘤耐药性。…”
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