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  1. 204721
  2. 204722

    Chromosome-level genome assembly of tetraploid Chinese cherry (Prunus pseudocerasus) by Wei Zhang, Jing Wang, Xuncheng Wang, Xuwei Duan, Junbo Peng, Xiaoming Zhang, Qikai Xing, Kaichun Zhang, Jiye Yan

    Published 2025-01-01
    “…In this study, we report a high-quality chromosome-scale genome assembly for Chinese cherry ‘Duiying’, by combining PacBio HiFi, Bionano and Hi-C sequencing data. The assembled genome has a size of 1035.19 Mb, with a scaffold N50 of 28.99 Mb, and 978.61 Mb (94.54%) assembled into 32 pseudochromosomes. …”
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  3. 204723
  4. 204724
  5. 204725
  6. 204726
  7. 204727
  8. 204728

    NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model by Ismail M Meraz, Mourad Majidi, Renduo Song, Feng Meng, Lihui Gao, Qi Wang, Jing Wang, Elizabeth J Shpall, Jack A Roth

    Published 2025-02-01
    “…The antitumor effect was correlated with increased infiltration of human cytotoxic-T, HLA-DR+DC, CD11c+DC, and downregulation of myeloid and regulatory-T cells in TME. …”
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  9. 204729

    Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia by Jana Lücht, Nele Rolfs, Sylvia J. Wowro, Felix Berger, Katharina R. L. Schmitt, Giang Tong

    Published 2021-01-01
    “…Cells were maintained at either normothermia (37°C) or cooled to 33.5°C, 1 h after experimental start. …”
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    Article
  10. 204730
  11. 204731
  12. 204732

    15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity by Kan Chen, Jingjing Li, Junshan Wang, Yujing Xia, Weiqi Dai, Fan Wang, Miao Shen, Ping Cheng, Yan Zhang, Chengfen Wang, Jing Yang, Rong Zhu, Huawei Zhang, Yuanyuan Zheng, Jie Lu, Zhuoyi Fan, Yingqun Zhou, Chuanyong Guo

    Published 2014-01-01
    “…Materials and Methods. In vivo, Balb/C mice were injected with ConA (25 mg/kg) to induce acute autoimmune hepatitis, and 15d-PGJ2 (10 μg or 25 μg) was administered 1 h before the ConA injection. …”
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  13. 204733
  14. 204734
  15. 204735
  16. 204736
  17. 204737
  18. 204738

    Mechanism of Qingjie Fuzheng Granules on alleviating 5-FU chemotherapy-induced intestinal mucositis in a mouse model of Colorectal Cancer by regulating Cathepsin B/NLRP3 pathway by Yuan Yingfei, Lin Jiumao, Lin Minghe, Zhao Jinyan, Chen Xuzheng, Liu Jinhong, Zhu Xiaoqin

    Published 2024-01-01
    “…ObjectiveTo investigate the therapeutic effect and mechanism of Qingjie Fuzheng Granules on 5-FU chemotherapy-induced intestinal mucositis in a mouse model of Colorectal Cancer based on Cathepsin B/NLRP3 pathway.MethodsTwenty-four male BALB/c mice were inoculated with CT26 cells subcutaneously in the axillary of the right forelimb to construct a mouse model of colorectal cancer subcutaneous xenograft. …”
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  19. 204739
  20. 204740