Human Mesenchymal Stromal Cells Transplantation May Enhance or Inhibit 4T1 Murine Breast Adenocarcinoma through Different Approaches by T. Jazedje, A. L. Ribeiro, M. Pellati, H. M. de Siqueira Bueno, G. Nagata, M. Trierveiler, E. G. Rodrigues, M. Zatz

“…In an attempt to clarify the contradictory results reported in the literature and the possible role of human fallopian tube Mesenchymal Stromal Cells (htMSCs) against breast cancer, the aim of this study was to evaluate the clinical effect of htMSCs in murine mammary adenocarcinoma using two different approaches: (1) coinjections of htMSCs and 4T1 murine tumor cell lineage and (2) injections of htMSCs in mice at the initial stage of mammary adenocarcinoma development. …”
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Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity by Sophia Lazar, Jeremy G.T. Wurtzel, Shayan Askari, Matthew Cooper, Xuefei Zhao, Peisong Ma, Lawrence E. Goldfinger

“…Female Ago2-deleted platelets selectively showed downregulation of a protein cohort established in breast cancer cells to be transcriptionally regulated by estrogen receptor-beta coupled to Ago2, whereas male Ago2-deleted platelets did not. …”
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Bioinformatics Analysis of the Human Surfaceome Reveals New Targets for a Variety of Tumor Types by André L. Fonseca, Vandeclécio L. da Silva, Marbella M. da Fonsêca, Isabella T. J. Meira, Thayná E. da Silva, José E. Kroll, André M. Ribeiro-dos-Santos, Cléber R. Freitas, Raimundo Furtado, Jorge E. de Souza, Beatriz Stransky, Sandro J. de Souza

“…Moreover, we present evidence that a three-gene set—WNT5A, CNGA2, and IGSF9B—can be used as a signature associated with shorter survival in breast cancer patients. The data made available here will help the community to develop more efficient diagnostic and therapeutic tools for a variety of tumor types.…”
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DIAGNOSTICS OF BONE METABOLISM DISORDERS IN ONCOLOGICAL DISEASES by O. I. Apolikhin, B. Y. Alekseev, A. V. Sivkov, N. G. Keshishev, A. A. Trudov, E. Z. Rabinovich, A. A. Kachmazov

“…Patients with myeloma, breast cancer, prostate, thyroid, bladder and lung have very high risk of development of bone lesions and related complications. …”
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Tumor Microenvironment‐Responsive Nanoparticles Enhance IDO1 Blockade Immunotherapy by Remodeling Metabolic Immunosuppression by Mengna Wang, Yuhong Liu, Yanshi Li, Tao Lu, Min Wang, Zhaobo Cheng, Lin Chen, Tongling Wen, Min Pan, Guohua Hu

“…Mechanistically, HMP1G NPs downregulated tumor cell‐derived IDO1 via the aryl hydrocarbon receptor/signal transducer and activator of transcription 3/interleukin signaling axis to improve kynurenine/tryptophan metabolism and immunosuppression. In a murine breast cancer model, treatment with HMP1G NPs elicited effective antitumor immunity and enhanced survival outcomes. …”
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Interleukin-10 Polymorphisms in Association with Prognosis in Patients with B-Cell Lymphoma Treated by R-CHOP by Min Kyeong Kim, Kyong-Ah Yoon, Eun Young Park, Jungnam Joo, Eun Young Lee, Hyeon-Seok Eom, Sun-Young Kong

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Treatment of metastatic brain lesion by A. M. Zaytsev, M. I. Kurzhupov, E. A. Potapova, O. N. Kirsanova

“…Metastases of colorectal cancer identified in 7.8%, cases of lung cancer in 34%, melanoma 9.3 %, breast cancer in 26%, kidney cancer in 11%, with non-identified primary tumor in 4.5%, other tumors accounted for 6.7%. …”
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Evaluation of maSSS/maSES-PEG2-RM26 for their potential therapeutic use after labeling with Re-188. Could their [99mTc]Tc-labeled counterparts be used to estimate dosimetry? by Panagiotis Kanellopoulos, Quanyi Yu, Abouzayed Abouzayed, Ekaterina Bezverkhniaia, Vladimir Tolmachev, Anna Orlova

“…Abstract Background Gastrin releasing peptide receptor (GRPR)-directed radiopharmaceuticals for targeted radionuclide therapy may be a very promising addition in prostate and breast cancer patient management. Aiming to provide a GRPR-targeting theranostic pair, we have utilized the Tc-99m/Re-188 radiometal pair, in combination with two bombesin based antagonists, maSSS-PEG2-RM26 and maSES-PEG2-RM26. …”
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Biosynthesis of reduced graphene oxide using Turbinaria ornata and its cytotoxic effect on MCF‐7 cells by K. M. Smita, L. Stanley Abraham, V. Ganesh Kumar, Raguraman Vasantharaja, R. Thirugnanasambandam, Ajit Antony, K. Govindaraju, T. Senthil Velan

“…Hence, this study results in an efficient green reductant for producing rGO nanosheets that possess cytotoxicity against breast cancer cells.…”
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A community-based approach to address lung cancer screening disparities in the black community using the Witness Project® framework: development and pilot trial by Lisa Carter-Bawa, Jamie S. Ostroff, Deborah O. Erwin, Elan N. Shoulders, Detric Johnson, Mikhalya Brown, Francis Valenzona, Lina Jandorf

“…Methods Utilizing a user-centered design and guided by the original Witness Project® framework – an evidence-based lay health advisor intervention program originally developed to increase knowledge and awareness about breast cancer risk and screening in the Black community and later trans-created to the cervical and colorectal cancer screening contexts - Witness Project® Lung was developed and refined through qualitative input from key stakeholders in the Black faith community. …”
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Effect of auriculotherapy on anxiety-fatigue and sleep disturbances in cancer patients: A scoping review by Silmara de Oliveira Silva, Vinicius dos Santos Lemos Pereira, Mariane Elivânia Silva, Jucielly Ferreira da Fonseca, Maria Carolina Batista da Silva, Roberta Paolli de Paiva Oliveira Arruda Camara, Rodrigo Assis Neves Dantas, Daniele Vieira Dantas

“…Asian countries were highly represented (62,5 %), followed by Latin America (12,5 %). Breast cancer was the most common tumor type, accounting for 68,75 %. …”
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pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG by Jing Wu, Shuang Li, Tete Li, Xinping Lv, Mingyou Zhang, Guoxia Zang, Chong Qi, Yong-Jun Liu, Liang Xu, Jingtao Chen

“…Our previous study demonstrated that pDCs activated by the TLR7 ligand imiquimod (IMQ) and the TLR9 ligand CpG A can kill breast cancer cells in vitro and inhibit tumor growth in vivo. …”
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The current and future cancer burden in the Gulf Cooperation Council (GCC) countries by Saleh A. Alessy, Saleh A. Alqahtani, Jerome Vignat, Amid Abuhmaidan, Amani E. L. Basmi, Najla Al Lawati, Ameera Ali A‐Nooh, Wael Shelpai, Samar Alhomoud, Ali Al‐Zahrani, Freddie Bray, Ariana Znaor

“…Colorectal (14%) followed by breast cancer (9%) were the leading causes of cancer death, though the magnitude of rates of the major cancer types varied substantially across the GCC countries. …”
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Parameter space exploration within dynamic simulations of signaling networks by Cristina De Ambrosi, Annalisa Barla, Lorenzo Tortolina, Nicoletta Castagnino, Raffaele Pesenti, Alessandro Verri, Alberto Ballestrero, Franco Patrone, Silvio Parodi

“…The core of the article deals with a Molecular Interaction Map (MIM), a network of biochemical interactions involved in a small signaling-network sub-region relevant in breast cancer. We explored robustness/sensitivity to random perturbations. …”
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Antibiofilm and Anticancer Activity of Multi-Walled Carbon Nanotubes Fabricated with Hot-Melt Extruded Astaxanthin-Mediated Synthesized Silver Nanoparticles by You HS, Jang YS, Sathiyaseelan A, Ryu SJ, Lee HY, Baek JS

“…MWCNT-AST showed higher anticancer activity against breast cancer cells (MDA-MB-231) than MWCNT-Ag, and lower toxicity in normal cells HaCaT and NIH3T3.Conclusion: MWCNT-AST exhibits higher antioxidant, antibiofilm, and anticancer activities than MWCNT-Ag, and exhibits lower toxicity to normal cells. …”
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An experimental study of the effects of SNPs in the TATA boxes of the <i>GRIN1, ASCL3</i> and <i>NOS1</i> genes on interactions with the TATA-binding protein by E. B. Sharypova, I. A. Drachkova, I. V. Chadaeva, M. P. Ponomarenko, L. K. Savinkova

“…For example, ASCL3 is overexpressed in breast cancer, and NOS1, in ovarian cancer cell lines. …”
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Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle by Vishnu Kumarasamy, Jianxin Wang, Michelle Roti, Yin Wan, Adam P. Dommer, Hanna Rosenheck, Sivasankar Putta, Alec Trub, John Bisi, Jay Strum, Patrick Roberts, Seth M. Rubin, Costakis Frangou, Karen McLean, Agnieszka K. Witkiewicz, Erik S. Knudsen

“…The co-expression of these genes occurs in breast cancer patients highlighting their clinical significance as predictive biomarkers for CDK2-targeted therapies. …”
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نقش حمایت اجتماعی بر کیفیت زندگی در بیماران مبتلا به سرطان پستان: مرور نظام‌مند by وحید نهتانی, نوشین پیمان

“…کلمات کلیدی مرتبط "Breast Cancer" AND "Social Support" AND "Quality Of Life" بود. …”
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Strategies for H-score Normalization of Preanalytical Technical Variables with Potential Utility to Immunohistochemical-Based Biomarker Quantitation in Therapeutic Reponse Diagnost... by William E. Pierceall, Michele Wolfe, Jessica Suschak, Hua Chang, Yan Chen, Kam M. Sprott, Jeffery L. Kutok, Stella Quan, David T. Weaver, Brian E. Ward

“…In this study, we present data on two candidate calibrator nuclear-localized proteins, SNRPA and SnRNP70, with robust and consistent expression levels across breast cancers. Quantitative expression measurement of these two candidate biomarkers may potentially be used to eliminate the effect of differences in preanalytic processing of specimens by normalizing H-scores derived from test biomarkers of interest. …”
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Reduced irradiation exposure areas enhanced anti-tumor effect by inducing DNA damage and preserving lymphocytes by Huiqin Chen, Yuan Li, Qiaofeng Shen, Guanqun Guo, Zhigang Wang, Hanyu Pan, Min Wu, Xueqing Yan, Gen Yang

“…In this study, we evaluated the antitumor efficacy of reduced-tumour-area radiotherapy (RTRT) , and explored the relationship between tumor control and immune preservation and the molecular mechanisms underlying of them. Methods In mouse breast cancer models, we compared the anti-tumor effects of RTRT and conventional radiotherapy (CNRT) by assessing tumor growth, metastasis, and survival rates. …”
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