Potentiation of Doxorubicin Cytotoxicity Utilizing Clarithromycin Loaded-PEGylated Liposomes by Islam Alfreahat MS, Hamdi Nsairat PhD, Ibrahim Deeb Aldeeb PhD, Ali Al-Samydai PhD, Walhan Alshaer PhD

“…Background Doxorubicin (DOX) is a potent chemotherapeutic agent for breast cancer, but its effectiveness is often diminished by resistance mechanisms, particularly through p-glycoprotein (P-gp) mediated drug efflux. …”
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Protocol for perfusing human axillary lymph nodes ex vivo to study structure and function in real time by Amy Llewellyn, Rachel Barrow-McGee, Julia Stevenson, Jasmine Gore, Kalnisha Naidoo

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Fractionated radiotherapy initiated at the early stage of bone metastasis is effective to prolong survival in mouse model by Yun Zhang, Zhunyi Gao, Ziwei Qi, Jiahe Xu, Jiao Xue, Lujie Xiong, Junhui Wang, Yuhui Huang, Songbing Qin

“…Background and purpose Bone metastasis is common for breast cancer and associated with poor prognosis. Currently, radiotherapy (RT) serves as the standard treatment for patients exhibiting symptoms of bone metastasis to alleviate pain. …”
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Bilateral prophylactic mastectomy: should we preserve the pectoral fascia? Protocol of a Dutch double blinded, prospective, randomised controlled pilot study with a within-subject... by Cornelis Verhoef, Linetta B Koppert, Marloes E Clarijs, Laurentine S E van Egdom, Dalibor Vasilic, T. van Dalen, C. de Betue, J. Rothbarth, E.V.E. Madsen, L.M. Beelen, M.A.M. Mureau, E.M.L. Corten, A.J.M. Luijsterburg, M.J. Hop, H.M. Zuijdendorp, N.A.S. Posch, C.M.C.A. van Laarhoven, M. de Kraker

“…Introduction Bilateral prophylactic mastectomy (BPM) in women with a high risk of developing breast cancer has shown to provide the greatest risk reduction. …”
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CGH, cDNA and Tissue Microarray Analyses Implicate FGFR2 Amplification in a Small Subset of Breast Tumors by Mervi Heiskanen, Juha Kononen, Maarit Bärlund, Joachim Torhorst, Guido Sauter, Anne Kallioniemi, Olli Kallioniemi

“…Multiple regions of the genome are often amplified during breast cancer development and progression, as evidenced in a number of published studies by comparative genomic hybridization (CGH). …”
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Brain Stroke Detection by Microwaves Using Prior Information from Clinical Databases by Natalia Irishina, Aurora Torrente

“…Microwave tomographic imaging is an inexpensive, noninvasive modality of media dielectric properties reconstruction which can be utilized as a screening method in clinical applications such as breast cancer and brain stroke detection. For breast cancer detection, the iterative algorithm of structural inversion with level sets provides well-defined boundaries and incorporates an intrinsic regularization, which permits to discover small lesions. …”
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Metformin increases mammographic breast density: a randomized controlled trial by Sadaf Alipour, Ladan Hosseini, Zohreh Forootan, Hadith Rastad, Leila Bayani, Mahboubeh Abedi, Bita Eslami

“… Background Mammographic breast density (MBD) is directly related to the risk of breast cancer. In vivo and in vitro studies have shown that metformin can reduce the proliferation and growth of breast cancer tissue. …”
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Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells by Amanda C. Stacer, Hanxiao Wang, Joseph Fenner, Joseph S. Dosch, Anna Salomonnson, Kathryn E. Luker, Gary D. Luker, Alnawaz Rehemtulla, Brian D. Ross

“…Breast cancer cells with low proteasome activity had greater local tumor formation and metastasis in immunocompromised and immunocompetent mice. …”
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Impact of the Implementation of a Postgraduate Mastology Course in the Province of Cienfuegos by Lidia Torres Ajá, Miriam Iglesias León, Carlos Zerquera Álvarez

“…<strong>Background:</strong> Cuban medical universities are aimed at the social formation of general practitioners who incorporate knowledge and skills that allow them to develop an appropriate professional performance when facing health issues, such as breast cancer. Promoting their postgraduate training is highly important. …”
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Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…While increased MITF expression in MDSCs promoted breast cancer progression and CD4+ or CD8+ T-cell dysfunction, decreased MITF expression in MDSCs suppressed tumor progression and enhanced T-cell activation. …”
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Faktor Yang Mempengaruhi Kepatuhan Berobat Pasien Yang Diterapi Dengan Tamoxifen Setelah Operasi Kanker Payudara by Arif Budiman, Daan Khambri, Hafni Bachtiar

“…<br />Keywords:Compliance, tamoxifen, breast cancer.</p>…”
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Malignant Fibrous Histiocytoma of the Breast in Young Male Patient: A Case Report and a Review of the Literature by Esengul Kocak Uzel, Metin Figen, Tuba Tulin Bek, Kubilay Inanc, Senem Onder, Hazim orhan Kizilkaya

“…Malignant Fibrous Histiocytoma (MFH) is a fairly common tumor in the deep soft tissues: the most frequent primary sites are the lower (49%) and upper (19%) limbs, but it has been reported even in the retroperitoneum and abdomen (16%), while localization in the breast is extremely rare (1-2). Breast cancer is rarely seen in males, accounts for approximately 1% of all breast cancer, and the breast sarcomas constitute less than 1% of breast tumors in both sexes. …”
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Nuclear DNA Content of Fine Needle Aspirates of Invasive Ductal Carcinomas of the Breast by Sudip Sarker, Allan Spigelman, Marjorie Walker, Dulcie Coleman

“…Patients with aggressive breast cancers benefit from chemotherapy prior to surgery. …”
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Our first experience of prepectoral reconstruction of the mammary gland using a mesh polypropylene implant by D. N. Rovenskikh, S. A. Usov, S. V. Petrosyants

“…Case-series of 6 patients with luminal breast cancer T1–2N0M0 aged from 34 to 47 years. IPPBR was performed after subcutaneous mastectomy (nipple sparing in 2 cases). …”
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Coregistration of Ultrasonography and Magnetic Resonance Imaging with a Preliminary Investigation of the Spatial Colocalization of Vascular Endothelial Growth Factor Receptor 2 Exp... by Mary E. Loveless, Jennifer G. Whisenant, Kevin Wilson, Andrej Lyshchik, Tuhin K. Sinha, John C. Gore, Thomas E. Yankeelov

“…We present an ultrasonography (US)-magnetic resonance imaging (MRI) coregistration technique and examine its application in a preliminary multimodal, multiparametric study in a preclinical model of breast cancer. Nine mice were injected with 67NR breast cancer cells and imaged 6 and 9 days later with 4.7 T MRI and high-frequency US. …”
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Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo by Yasaman Ardeshirpour, Amir H. Gandjbakhche, Laleh Najafizadeh

“…In vivo optical imaging is being conducted in a variety of medical applications, including optical breast cancer imaging, functional brain imaging, endoscopy, exercise medicine, and monitoring the photodynamic therapy and progress of neoadjuvant chemotherapy. …”
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Tumor hypoxia evidences the differential regulation of Mdm2-p53 axis by PTEN in tumor derived vs. normal endothelial cells by Kinga Wilkus-Adamczyk, Klaudia Brodaczewska, Claudine Kieda

“…This study aims to compare ECs derived from breast cancer (HBCa.MEC) site with those derived from the healthy breast tissue (HBH.MEC). …”
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Synthesis and Antitumor Activity of Novel Pyridoxine-Based Bioisosteric Analogs of trans-Stilbenes by Mikhail V. Pugachev, Thang T. N. Nguyen, Timur M. Bulatov, Roman S. Pavelyev, Alfia G. Iksanova, Oksana V. Bondar, Konstantin V. Balakin, Yurii G. Shtyrlin

“…Two compounds demonstrated high activity against the estrogen-dependent MCF-7 (breast cancer) cell line with IC50 in the range of 1.9–7.9 µM and very good selectivity for other studied normal and tumor cells, including the estrogen receptor negative MDA-MB-231 breast cancer cells. …”
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Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall by Chantal Atallah, Gulbeyaz Altinel, Lili Fu, Jocelyne Arseneau, Atilla Omeroglu

“…However, this has to be considered in the differential diagnosis of nodal disease in patients with a history of breast cancer. Here, we report the case of a 73-year-old female with a past medical history of breast cancer, presenting with an ipsilateral axillary metastatic carcinoma. …”
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Enhanced preoperative prediction of breast lesion pathology, prognostic biomarkers, and molecular subtypes using multiple models diffusion-weighted MR imaging by Litong He, Feng Li, Yanjin Qin, Yuling Li, Qilan Hu, Zhiqiang Liu, Yunfei Zhang, Tao Ai

“…The diffusion parameters derived from these models can effectively assist in distinguishing prognostic factors and molecular subtypes of breast cancer.…”
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