New Immunotherapeutic Approaches for Glioblastoma by Gustavo Ignacio Vázquez Cervantes, Dinora F. González Esquivel, Saúl Gómez-Manzo, Benjamín Pineda, Verónica Pérez de la Cruz

“…Glioblastoma (GBM) is the most common primary malignant brain tumor with a high mortality rate. The current treatment consists of surgical resection, radiation, and chemotherapy; however, the median survival rate is only 12–18 months despite these alternatives, highlighting the urgent need to find new strategies. …”
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Advancements in the Use of Hydrogels for Regenerative Medicine: Properties and Biomedical Applications by Andrea Revete, Andrea Aparicio, Bruno A. Cisterna, Javier Revete, Luis Luis, Ernesto Ibarra, Edwin A. Segura González, Jay Molino, Diego Reginensi

“…Hydrogels represent a potential alternative to regenerating tissue lost after removing a brain tumor and/or brain injuries. This reason presents them as an exciting alternative to highly complex human physiological problems, such as injuries to the central nervous system and neurodegenerative disease.…”
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Glioblastoma. Past, present and future by Adriel Herrero Díaz, Luis Manuel Abreu Pereira, Ilian Esteban Tarife Romero, Diana Rosa González Tamayo

“…<p>Glioblastoma is the most advanced, common and malignant stage of primary brain tumors in adults. It represents about 57% of all glial tumors. …”
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Gene Therapy for Glioblastoma Multiforme by Smit Shah, Joshua Green, Shantelle A. Graff, Qi Li, John D. Heiss

“…Glioblastoma multiforme (GBM) is a devastating, aggressive primary brain tumor with poor patient outcomes and a five-year survival of less than 10%. …”
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Glioblastoma Multiforme Stem Cells by Irena Dimov, Deasanka Tasic-Dimov, Irena Conic, Vladisav Stefanovic

“…Glioblastoma multiforme (GBM) is an aggressive, malignant, and lethal brain tumor, resistant to all current forms of treatment. …”
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Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models by Andrea Mancini, Alessandro Colapietro, Loredana Cristiano, Alessandra Rossetti, Vincenzo Mattei, Giovanni Luca Gravina, Giovanni Luca Gravina, Héctor Perez-Montoyo, Marc Yeste-Velasco, Jose Alfon, Carles Domenech, Claudio Festuccia

“…BackgroundGlioblastoma multiforme (GBM) is the most malignant adult brain tumor. Current standard of care treatments have very limited efficacy, being the patients´ overall survival 14 months and the 2-year survival rate less than 10%. …”
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Comparative analysis of pediatric SHH medulloblastoma DAOY spheres and adherent monolayers: implications for medulloblastoma research by Jana Klementová, Šárka Jarošová, Irina Danilová, Markéta Farníková, Josef Novotný, Marie Davídková, Martina Zíková

“…Abstract Medulloblastoma, the most prevalent brain tumor among children, requires a comprehensive understanding of its cellular characteristics for effective research and treatment. …”
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Toxic Epidermal Necrolysis Associated with Antiepileptic Drugs and Cranial Radiation Therapy by Shereen Elazzazy, Taghrid Abu Hassan, Ashraf El Seid, Cicy Mary Jacob

“…Although TEN is a rare toxicity, physicians should pay a special attention to the monitoring of brain tumor patients on antiepileptic prophylaxis during cranial irradiation; furthermore, patients should be counselled to notify their physicians if they develop any new or unusual symptoms.…”
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Glioma Stem Cells: Signaling, Microenvironment, and Therapy by Brandon D. Liebelt, Takashi Shingu, Xin Zhou, Jiangong Ren, Seul A. Shin, Jian Hu

“…Glioblastoma remains the most common and devastating primary brain tumor despite maximal therapy with surgery, chemotherapy, and radiation. …”
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Brain gliomas new transcriptomic discoveries from differentially expressed genes to therapeutic targets by Shiwen Pei, Zhiquan Jiang, Hongwei Cheng

“…Abstract Gliomas are a prevalent form of primary malignant brain tumor, yet the intricate molecular mechanisms underlying its pathogenesis remain unclear. …”
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PLIN1 suppresses glioma progression through regulating lipid metabolism by Kui Luo, Kai Zhuang, Hao Wu, Yuanbing Chen, Yi Liu, Fan Yang, Zhifei Wang

“…Abstract Glioma is a common and destructive brain tumor, which is highly heterogeneous with poor prognosis. …”
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Brain Midline Shift Measurement and Its Automation: A Review of Techniques and Algorithms by Chun-Chih Liao, Ya-Fang Chen, Furen Xiao

“…Shift of midline intracranial structures helps diagnosing intracranial lesions, especially traumatic brain injury, stroke, brain tumor, and abscess. Being a sign of increased intracranial pressure, MLS is also an indicator of reduced brain perfusion caused by an intracranial mass or mass effect. …”
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Brain CT image classification based on mask RCNN and attention mechanism by Shoulin Yin, Hang Li, Lin Teng, Asif Ali Laghari, Ahmad Almadhor, Michal Gregus, Gabriel Avelino Sampedro

“…The application of machine learning, and block-chain techniques into medical image retrieval, classification and auxiliary diagnosis has become one of the research hotspots at present. Brain tumor is one of the major diseases threatening human life. …”
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LncRNA-PVT1 enhances glucose metabolism of pediatric low-grade glioma cells through sponging miR-187-3p by Beibei Li, Zijian Feng, Yanyan Zheng

“…Studies have revealed critical roles of long non-coding RNAs (lncRNAs) in brain tumor progressions. Here, we aimed to investigate the clinical roles and molecular mechanisms of lncRNA PVT1 in PLGG. …”
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Discontiguous recurrences of IDH-wildtype glioblastoma share a common origin with the initial tumor and are frequently hypermutated by Malcolm F. McDonald, Sricharan Gopakumar, Tareq A. Juratli, Ilker Y. Eyüpoglu, Ganesh Rao, Jacob J. Mandel, Ali Jalali

“…Abstract Glioblastoma is the deadliest primary brain tumor, largely due to inevitable recurrence of the disease after treatment. …”
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Identification of CDKN3 overexpression as a marker of poor prognosis and potential therapeutic target in low-grade glioma by Hongbing Cheng, Xiao Meng, Yanhua Zhang, Pu Wang, Yucheng Lu

“…Abstract Low-grade glioma (LGG) is a primary, slow-growing brain tumor; however, its treatment and prognosis remain challenging. …”
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A Critical Review of Constraint-Induced Movement Therapy and Forced Use in Children With Hemiplegia by Jeanne Charles, Andrew M. Gordon

“…Hemiplegia is a physical impairment that can occur in childhood following head trauma, cerebral vascular accident or transient ischemic attack (stroke), brain tumor, or congenital or perinatal injury. One of the most disabling symptoms of hemiplegia is unilaterally impaired hand and arm function. …”
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Radiation-Induced Growth Retardation and Microstructural and Metabolite Abnormalities in the Hippocampus by Shaefali P. Rodgers, Janice A. Zawaski, Iman Sahnoune, J. Leigh Leasure, M. Waleed Gaber

“…Cranial radiotherapy (CRT) increases survival in pediatric brain-tumor patients but can cause deleterious effects. …”
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The role of reaction temperature in synthesizing clove-derived copper oxide nanoparticles for brain cancer treatment by Mehrnoosh Fakhredin, Fatemeh Shariatmadar Tehrani, Maryam Aliannezhadi

“…Notably, CuO NPs obtained at a reaction temperature of 50°C exhibited better primary properties, facilitating their potential application in cancer treatment. Brain tumors constitute a disproportionately significant contributor to the overall cancer mortality burden, particularly in cases where surgical intervention is not a viable treatment option. …”
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In vivo MRI visualization of growth and morphology in the orthotopic xenotrasplantation U87 glioblastoma mouse SCID model by E. L. Zavjalov, I. A. Razumov, L. A. Gerlinskaya, A. V. Romashchenko

“…The study of tumor formation and the evaluation of new therapies for GBM require accurate and reproducible experimental brain tumor animal models. In this study we used MRI for investigation of tumor morphology and growth dynamic in an orthopic xenotransplantation immunodeficient mouse model (SCID mouse line). …”
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