Alcohol and Suicide: Neurobiological and Clinical Aspects by Leo Sher

“…Dopaminergic dysfunction may play an important role in the pathophysiology of suicidal behavior in alcoholism. Brain damage and neurobehavioral deficits are associated with alcohol use disorders and may contribute to suicidal behavior in persons with alcohol dependence or abuse. …”
Get full text

Alcoholism, Korsakoff’s Syndrome and the Frontal Lobes by R. R. Jacobson

“…A new model is proposed of the pathophysiology of alcoholic brain damage and AKS which includes recent work on neurotransmitter sources and thalamo-frontal connections.…”
Get full text

A disproportionality analysis of FDA adverse event reporting system events for misoprostol by Li Yang, Wenting Xu

“…Although most AEs complied with the drug instruction, new AEs signals such as congenital aqueductal stenosis and congenital brain damage were also identified. Clinicians should make appropriate evaluation when using misoprostol, closely monitor the indicators of patients, and have appropriate countermeasures for possible adverse events.…”
Get full text

Bipolar Disorder and Multiple Sclerosis: A Case Series by Youssef Sidhom, Mouna Ben Djebara, Yosr Hizem, Istabrak Abdelkefi, Imen Kacem, Amina Gargouri, Riadh Gouider

“…MRI lesions suggest the possible implication of local MS-related brain damage in development of pure “psychiatric fits” in MS. …”
Get full text

Cognitive Impairment in Heart Failure by Efthimios Dardiotis, Gregory Giamouzis, Dimos Mastrogiannis, Christina Vogiatzi, John Skoularigis, Filippos Triposkiadis, Georgios M. Hadjigeorgiou

“…Although the exact mechanisms remain unclear, microembolism, chronic or intermittent cerebral hypoperfusion, and/or impaired cerebral vessel reactivity that lead to cerebral hypoxia and ischemic brain damage seem to underlie the development of CI in HF. …”
Get full text

Spatiotemporal Pattern of Neuroinflammation After Impact-Acceleration Closed Head Injury in the Rat

“…<p>Inflammatory processes have been implicated in the pathogenesis of traumatic brain damage. We analyzed the spatiotemporal expression pattern of the proinflammatory key molecules: interleukin-1<mml:math alttext="$eta$"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, interleukin-6, tumor necrosis factor-<mml:math alttext="$alpha$"> <mml:mi>&#x03B1;</mml:mi> </mml:math>, and inducible nitric oxide synthase in a rat closed head injury (CHI) paradigm. 51 rats were used for RT-PCR analysis after CHI, and 18 for immunocytochemistry. …”
Get full text

Iodine Supplementation: Usage “with a Grain of Salt” by Alessandro Prete, Rosa Maria Paragliola, Salvatore Maria Corsello

“…Moreover, iodine supplementation during pregnancy in order to avoid brain damage in the newborn is considered a mainstay of preventive medicine. …”
Get full text

Thrombosed Fetal Dural Sinus Malformation: A Case Report by Tayseer Al Muteri, Muna Al Rawahi, Felipe Moretti

“…A postnatal diagnosis of thrombosis in the sinus was confirmed by MRI and venography. No brain damage or hydrocephalus was noted, and the neurological outcome was normal at 9 months of age. …”
Get full text

Cord Blood Bilirubin as a Predictor of Neonatal Hyperbilirubinemia by Saman Beg, Uzma Firdaus, Syed Manazir Ali

“…Some newborns experience noticeable, potentially dangerous bilirubin levels, which can directly increase the risk of severe brain damage, despite it being a benign, postnatal, transitory phenomenon. …”
Get full text

A Foreign Speech Accent in a Case of Conversion Disorder by Jo Verhoeven, Peter Mariën, Sebastiaan Engelborghs, Hugo D’Haenen, Peter De Deyn

“…This syndrome is generally related to focal brain damage. Only in few reported cases the Foreign Accent Syndrome is assumed to be of psychogenic and/or psychotic origin. …”
Get full text

Liver laceration as a post-cardiopulmonary resuscitation complication in a person with breast implants: a case report by Min-Jeong Cho

“…Electroencephalography showed generalized attenuation, indicating severe global brain damage. Liver injury is a relatively rare post-CPR complication, with an incidence of 0.6% according to a retrospective analysis of a cardiac arrest registry. …”
Get full text

APOPTOSIS MARKERS IN NEWBORN CHILDREN WITH MILD HYPOXIC DAMAGE OF CNS by D.H. Posternak

“…Meanwhile, the unidirectional changes of levels of the studied indicators in newborns with mild hypoxic damage of CNS are reflected by the severity of brain damage, and also indicates adequacy of the chosen methods for the detection of apoptosis.…”
Get full text

The Role of Air Pollution and Olfactory Dysfunction in Alzheimer’s Disease Pathogenesis by Louise Odendaal, Hazel Quek, Carla Cuní-López, Anthony R. White, Romal Stewart

“…It has been demonstrated that the olfactory system, responsible for smell perception and processing, acts as a potential gateway for airborne pollutants to inflict brain damage. This review aims to elucidate the relationship between air pollution, olfactory deterioration, and AD. …”
Get full text

Rehabilitation of Speech and Swallowing Disorder in a Patient With Severe Brain Injury in the Subacute Phase: A Case Report by Morteza Farazi, Niyayesh Aali, Seyed Majid Akhvan Hejazi

“…Background and Objectives: Swallowing disorder or dysphasia is often due to neuromuscular brain damage. Dysarthria is a speech movement disorder caused by damage to the central nervous system. …”
Get full text

Euglycemic diabetic ketoacidosis associated metabolic encephalopathy caused by dapagliflozin: a rare case report by Lulu Chu, Zhenhua Xi, Runzhi Ma, Weiliang Shi, Guoshen Yu

“…Due to paradoxically normal or slightly elevated serum glucose levels, it’s easy to be mimicked by cerebral infarction, structural brain damage, thus leading to delayed diagnosis and causing seriously irreversible brain injury. …”
Get full text

Spatiotemporal Pattern of Neuroinflammation After Impact-Acceleration Closed Head Injury in the Rat by Servan Rooker, Sebastian Jander, Jos Van Reempts, Guido Stoll, Philippe G. Jorens, Marcel Borgers, Jan Verlooy

“…Inflammatory processes have been implicated in the pathogenesis of traumatic brain damage. We analyzed the spatiotemporal expression pattern of the proinflammatory key molecules: interleukin-1β, interleukin-6, tumor necrosis factor-α, and inducible nitric oxide synthase in a rat closed head injury (CHI) paradigm. 51 rats were used for RT-PCR analysis after CHI, and 18 for immunocytochemistry. …”
Get full text

Activation of TLR4-Mediated NF𝜅B Signaling in Hemorrhagic Brain in Rats by Weiyu Teng, Lishu Wang, Weishuang Xue, Chao Guan

“…The present study firstly suggests that TLR4-mediated NF𝜅B signaling participates in the pathogenesis of ICH, which may become a therapeutic target for ICH-induced brain damage.…”
Get full text

Cerebral venous thrombosis and depression: a scoping review by Feras M. Almarshad, Dushad Ram

“…Cerebral venous thrombosis is a rare condition involving thrombus formation in the venous sinuses of the brain, leading to impaired venous drainage, increased intracranial pressure, and brain damage. Depression frequently accompanies cerebral venous thrombosis patients with varying prevalence and characteristics across studies. …”
Get full text

Inhibitory Effect on Cerebral Inflammatory Response following Traumatic Brain Injury in Rats: A Potential Neuroprotective Mechanism of N-Acetylcysteine by Gang Chen, Jixin Shi, Zhigang Hu, Chunhua Hang

“…The results suggest that post-TBI NAC administration may attenuate inflammatory response in the injured rat brain, and this may be one mechanism by which NAC ameliorates secondary brain damage following TBI.…”
Get full text

Kisspeptin is elevated in the brain after intracerebral haemorrhagic stroke by Saumya Maheshwari, In Hwa Um, Struan Donachie, Nafeesa Asghar, Karina McDade, Tracey Millar, David J. Harrison, Javier A. Tello

“…Whilst treatment options for ICH remain limited, the condition requires prompt identification and rapid intervention to reduce permanent brain damage, with diagnosis traditionally confirmed by CT imaging. …”
Get full text