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    Deciphering Metabolic Responses in Traumatic Brain Injury Patients With Different Severity Using 1H NMR-Based Serum Metabolomics by Huan Zhou, Dongdong Sun, Dongmei Wang, Zirui Zhu, Xuelian Hong, Rui Fang, Hua Wang, Minghui Li

    Published 2025-01-01
    “…The analysis of metabolites presents a promising opportunity to gain insight into the neuropathophysiology of individuals affected by traumatic brain injury (TBI). In order to elucidate the underlying pathophysiologic mechanisms and identify serum biomarkers associated with TBI, we conducted a comprehensive investigation utilizing a 1H nuclear magnetic resonance (NMR)–based metabolomics approach and ELISA analysis of serum samples obtained within 24 h postinjury from a cohort of participants with varying degrees of TBI severity. …”
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    Inhibitory Effect on Cerebral Inflammatory Response following Traumatic Brain Injury in Rats: A Potential Neuroprotective Mechanism of N-Acetylcysteine by Gang Chen, Jixin Shi, Zhigang Hu, Chunhua Hang

    Published 2008-01-01
    “…Although N-acetylcysteine (NAC) has been shown to be neuroprotective for traumatic brain injury (TBI), the mechanisms for this beneficial effect are still poorly understood. …”
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