Striatal Injury with 6-OHDA Transiently Increases Cerebrospinal GFAP and S100B by Cristiane Batassini, Núbia Broetto, Lucas Silva Tortorelli, Milene Borsoi, Caroline Zanotto, Fabiana Galland, Tadeu Mello Souza, Marina Concli Leite, Carlos-Alberto Gonçalves

“…Both glial fibrillary acidic protein (GFAP) and S100B have been used as markers of astroglial plasticity, particularly in brain injury; however, they do not necessarily change in the same time frame or direction. …”
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Susceptibility map-weighted MRI can distinguish tremor-dominant Parkinson’s disease from essential tremor by Sungyang Jo, Chong Hyun Suh, Sangjin Lee, Jihyun Lee, MyungKi Yoon, Hwon Heo, Woo Hyun Shim, Sang Joon Kim, Eung Yeop Kim, Sun Ju Chung

“…Patients with PD exhibit loss of the dorsal nigral hyperintensity on brain magnetic resonance imaging (MRI). Novel MRI-based approaches, including susceptibility map-weighted imaging (SMwI), allow visualization of the dorsal nigral hyperintensity at an increased resolution. …”
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Integrated analysis of chromatin and transcriptomic profiling of the striatum after cerebral hypoperfusion in mice by Shijia Le, Fengyiyang Xu, Zhi Luo, Weihao Shi, Shuangshuang Lu, Zengyu Zhang, Zimin Guo, Wenshi Xu, Mingqi Yang, Tianyi Li, Xu Li, Kun Liang, Lei Zhu

“…This study investigated the molecular and epigenetic changes in the striatum, a brain region critical for motor function and cognition, following chronic hypoperfusion using a bilateral common carotid artery stenosis (BCAS) model in mice. …”
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Default mode network-basal ganglia network connectivity predicts the transition to postherpetic neuralgia by Ying Wu, Chao Wang, Wei Qian, Lieju Wang, Lina Yu, Minming Zhang, Min Yan

“…However, there is a lack of knowledge regarding the relationship between the brain network connectivity during the acute period and disease prognosis. …”
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Gait characteristics in idiopathic normal pressure hydrocephalus: a review on the effects of CSF tap test and shunt surgery by Iva Hereitová, Alessandra Griffa, Gilles Allali, Tomáš Dorňák

“…Abstract Background Idiopathic normal pressure hydrocephalus (iNPH) is a progressive disease characterized by disproportionate ventricular enlargement at brain imaging with gait disturbance and an increased risk of falling. …”
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Adolescent mice exposed to TBI developed PD-like pathology in middle age by Rong Sha, Mingzhe Wu, Pengfei Wang, Ziyuan Chen, Wei Lei, Shimiao Wang, Shun Gong, Guobiao Liang, Rui Zhao, Yingqun Tao

“…Abstract Traumatic brain injury (TBI) is identified as a risk factor for Parkinson’s disease (PD), which is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra (SN). …”
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Comparing different montages of transcranial direct current stimulation on dual-task walking and cortical activity in chronic stroke: double-blinded randomized controlled trial by Pei-Ling Wong, Yea-Ru Yang, Shun-Chang Tang, Shih-Fong Huang, Ray-Yau Wang

“…Abstract Background Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation to modulate cortical activity for improving motor function. …”
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Acute beneficial effects of a functional energy shot on cognitive performance and mood states during cognitively demanding task performance: a randomized, double-blind, placebo-con... by Olivia K. O’Shea, Olivia K. O’Shea, Nathan Lawley, Anna Azzopardi, Allison Gutkowski, Michelle Murphy Niedziela, Rachel Horn, David O. Kennedy, Jason Adamson

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Resting state EEG in young children with Tuberous Sclerosis Complex: associations with medications and seizures by Caitlin C. Clements, Anne-Michelle Engelstad, Carol L. Wilkinson, Carly Hyde, Megan Hartney, Alexandra Simmons, Helen Tager-Flusberg, Shafali Jeste, Charles A. Nelson

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Insights Into the Role of Bmi‐1 Deregulation in Promoting Stemness and Therapy Resistance in Glioblastoma: A Narrative Review by Fatima Shaalan, Nissrine Ballout, Wafaa Takash Chamoun

“…ABSTRACT Background Glioblastoma (GBM) is the most common primary brain tumor in adults and has a median survival of less than 15 months. …”
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Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats by Yonglin Zhao, Yahui Zhao, Ming Zhang, Junjie Zhao, Xudong Ma, Tingqin Huang, Honggang Pang, Jiaxi Li, Jinning Song

“…Recent studies show that toll-like receptor 4 (TLR4) plays a critical role in promoting adaptive immune responses and have been shown to be associated with brain damage. The purpose of this study was to investigate the role of the TLR4 signalling pathway in secondary axonal injury in the cortices of DAI rats. …”
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Optimal trajectory of the neuroendoscope for third ventricle pavement access by Joana Sousa, Susana Maria Silva, Susana Maria Silva, Hélio Alves, Bruno Carvalho, Bruno Carvalho, José Maria Sousa, Manuel J. Ferreira-Pinto, Manuel J. Ferreira-Pinto, Manuel J. Ferreira-Pinto, Manuel J. Ferreira-Pinto, José Paulo Andrade, José Paulo Andrade

“…Background and aimEndoscopic Third Ventriculostomy (ETV) is used to treat hydrocephalus, an abnormal cerebrospinal fluid accumulation in brain ventricles. By defining a new trajectory and entry point interval, we aim to establish a standardized approach for FreeHand ETV, a vital technique when specialized tools are unavailable, or during emergencies.Methods187 MRIs were analyzed, with 30 having hydrocephalus. …”
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Determinants of well-being and their interconnections in Australian general practitioners: a qualitative study by Nick Glozier, Ian B Hickie, Christiane Klinner, Alyssa Milton, Diana Naehrig, Louise Acland, Brendan Goodger

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Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men by Carla Basualto-Alarcón, Paola Llanos, Gerardo García-Rivas, Mayarling Francisca Troncoso, Daniel Lagos, Genaro Barrientos, Manuel Estrada

“…SHBG is produced mainly in the liver, but it can also be expressed in several tissues including the brain, fat tissue, and myocardium. Expression of SHBG is controlled by peroxisome proliferator-activated receptor γ (PPARγ) and AMP-activated protein kinase (AMPK). …”
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An experimental study of the effects of SNPs in the TATA boxes of the <i>GRIN1, ASCL3</i> and <i>NOS1</i> genes on interactions with the TATA-binding protein by E. B. Sharypova, I. A. Drachkova, I. V. Chadaeva, M. P. Ponomarenko, L. K. Savinkova

“…The effect of allele A of the –27G&gt;A SNP (rs1195040887) in the NOS1 promoter is suggestive of an increased risk of ischemic damage to the brain in carriers. A comparison of experimental TBP–TATA affinity values (KD) of wild-type and minor alleles with predicted ones showed that the data correlate well (linear correlation coefficient r = 0.94, p &lt; 0.01).…”
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Effect of lethal yellow (AY) mutation and photoperiod alterations on mouse behavior by E. Y. Bazhenova, D. V. Fursenko, N. V. Khotskin, I. E. Sorokin, A. V. Kulikov

“…The lethal yellow (AY) mutation causes ectopic expression of agouti protein in the brain. Mice heterozygous for AY mutation (AY/a) are obese compared to their wild-type littermates (a/a). …”
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Improving natural red pigment production by Streptomyces phaeolivaceus strain GH27 for functionalization of textiles with in silico ADME prediction by Gehad H. El Sayed, Mohamed Fadel, Rasha Fouad, Hend M. Ahmed, Ahmed A. Hamed

“…It exhibited intermediate synthetic accessibility, exceptional permeability and absorption, elevated gastrointestinal absorption, and blood–brain barrier penetration; nonetheless, it did not adhere to the medicinal chemistry rule of three. …”
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A data driven approach for soft tissue biomarker identification linked to Chiari-like malformation and syringomyelia by Jake Cumber, Jake Cumber, Emma Scales-Theobald, Emma Scales-Theobald, Clare Rusbridge, Clare Rusbridge, Clare Rusbridge, Kevin Wells, Kevin Wells

“…CM is characterized by overcrowding of the brain and cervical spinal cord and is predisposed by skull-base shortening and miniaturization with brachycephalic toy dogs overwhelmingly represented. …”
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Th17 Cell Response in SOD1G93A Mice following Motor Nerve Injury by Allen Ni, Tao Yang, Nichole A. Mesnard-Hoaglin, Rafael Gutierrez, Evan B. Stubbs, Susan O. McGuire, Virginia M. Sanders, Kathryn J. Jones, Eileen M. Foecking, Junping Xin

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Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis by Louisane Desbiens, Catherine Lapointe, Marjan Gharagozloo, Shaimaa Mahmoud, Gunnar Pejler, Denis Gris, Pedro D’Orléans-Juste

“…Finally, whereas EAE triggered significant increases in brain levels of mMCP-4 mRNA and immunoreactive ET-1 in WT mice, the latter peptide was reduced to basal levels in mMCP-4 KO congeners. …”
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