Maintenance of a Schwann-Like Phenotype in Differentiated Adipose-Derived Stem Cells Requires the Synergistic Action of Multiple Growth Factors by Alice E. Mortimer, Alessandro Faroni, Mahmut A. Kilic, Adam J. Reid

“…Cells treated with GGF-2 alone reverted to a stem cell morphology and did not stimulate the production of brain-derived neurotrophic factor (BDNF), regardless of the concentration of GGF-2 in the growth medium. …”
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Symptomatic vigabatrin‐associated MRI toxicity is associated with simultaneous hormonal therapy among patients with infantile spasms by Rujuta Sathe, Gyaneshwar Shrestha, Aria Terango, David Tabibzadeh, Rajsekar R. Rajaraman, Hiroki Nariai, Shaun A. Hussain

“…Abstract Vigabatrin‐associated brain abnormalities on MRI (VABAM) are observed in approximately 20% of children who receive vigabatrin for treatment of infantile epileptic spasms syndrome. …”
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Super High Contrast USPIO-Enhanced Cerebrovascular Angiography Using Ultrashort Time-to-Echo MRI by Liam Timms, Tianyi Zhou, Ju Qiao, Codi Gharagouzloo, Vishala Mishra, Rita Maria Lahoud, John W. Chen, Mukesh Harisinghani, Srinivas Sridhar

“…We present first-in-human clinical results of the Quantitative Ultrashort Time-to-Echo Contrast Enhanced (QUTE-CE) MRA technique using the superparamagnetic iron oxide nanoparticle agent ferumoxytol for vascular imaging of the head/brain in 15 subjects at 3.0T. The QUTE-CE MRA method was implemented on a 3T scanner using a stack-of-spirals 3D Ultrashort Time-to-Echo sequence. …”
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Modelling the Transmission Dynamics of Meningitis among High and Low-Risk People in Ghana with Cost-Effectiveness Analysis by Nicholas Kwasi-Do Ohene Opoku, Reindorf Nartey Borkor, Andrews Frimpong Adu, Hannah Nyarkoah Nyarko, Albert Doughan, Edwin Moses Appiah, Biigba Yakubu, Isabel Mensah, Samson Pandam Salifu

“…Meningitis is an inflammation of the meninges, which covers the brain and spinal cord. Every year, most individuals within sub-Saharan Africa suffer from meningococcal meningitis. …”
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Advances in the Study of AI-assisted Diagnosis and Rehabilitation of ASD by Bosen MA, Xiaorong ZENG, Ran GONG, Farui LI

“…The AI-assisted diagnosis research analyzes relevant data mainly by training the artificial neural network. The data include: ①brain imaging data from the ASD group and the matched group.②multimodal data of speech, movements and facial expressions produced by infants or children with ASD and data of the diagnostic process. …”
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Montreal Cognitive Assessment and Modified Mini Mental State Examination in African Americans by Kaycee M. Sink, Suzanne Craft, S. Carrie Smith, Joseph A. Maldjian, Donald W. Bowden, Jianzhao Xu, Barry I. Freedman, Jasmin Divers

“…Five hundred and thirty African Americans with type 2 diabetes were enrolled in African American-Diabetes Heart Study-MIND, a cross-sectional study of cognition and structural and functional brain imaging. After excluding participants with possible cognitive impairment (n=115), mean (SD) MoCA and 3MSE scores are presented stratified by age and education. …”
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In vitro neuroprotective potentials of aqueous and methanol extracts from Heinsia crinita leaves by Ganiyu Oboh, Esther E. Nwanna, Sunday I. Oyeleye, Tosin A. Olasehinde, Opeyemi B. Ogunsuyi, Aline A. Boligon

“…The effects of the extracts on Fe2+-induced lipid peroxidation in rats’ brain homogenate, monoamine oxidase (MAO), Na+/K+-ATPase, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities were also assessed. …”
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0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors by Alessandro Fava, Francesco Centurelli, Giuseppe Scotti

“…The 8th-order filter, implemented with 4 cascaded instances of the proposed biquad filter, guarantees an attenuation higher than 30 dB at <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>/2 and 2f0 with a power consumption of 480 nW, and an area footprint of 0.152 mm2, thus satisfying the requirements to extract the epilepsy biomarker in closed-loop deep brain stimulation systems.…”
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Enhancing glioblastoma therapy: unveiling synergistic anticancer effects of Onalespib - radiotherapy combination therapy by Julia Uffenorde, Mehran Hariri, Eleftherios Papalanis, Annika Staffas, Josefine Berg, Bo Stenerlöw, Hanna Berglund, Christer Malmberg, Diana Spiegelberg, Diana Spiegelberg

“…BackgroundGlioblastoma (GBM) is the deadliest form of brain cancer, impacting both adults and children, marked by exceptionally high morbidity and mortality rates, even with current standard treatments such as surgery, radiation therapy, and chemotherapy. …”
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Impact of surrounding tissue-type and peri-electrode gap in stereoelectroencephalography guided (SEEG) radiofrequency thermocoagulation (RF-TC): a computational study by Santiago Collavini, Juan J. Pérez, Enrique Berjano, Mariano Fernández-Corazza, Silvia Oddo, Ramiro M. Irastorza

“…After adapting the model to clinical conditions, the simulation showed that: 1) Impedance roll-off limited the coagulation size but involved overheating (around 100 °C); 2) The type of tissue around the contacts (gray vs. white matter) had a moderate impact on the coagulation size (maximum difference 0.84 mm), and 3) the peri-electrode gap considerably altered the temperature distributions, avoided overheating, although the diameter of the coagulation zone was not very different from the no-gap case (<0.2 mm).Conclusions This study showed that computer modeling, especially subject- and scenario-specific modeling, can be used to estimate in advance the electrical and thermal performance of the RF-TC in brain tissue.…”
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A Case of Status Epilepticus in a Patient Experiencing an Acute Attack of Hereditary Angioedema by Danielle Weinberg, Steven Gayda, Kyle Hultz, Hanan Atia, Brian Kohen, Eric Boccio

“…Inpatient work-up included continuous video electroencephalography monitoring and magnetic resonance imaging of the brain, both of which were normal. The remainder of the inpatient course was uncomplicated, and the patient was discharged home neurologically intact. …”
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Functional segregation and dynamic integration of the corticotectal descending signal in rat by Hikaru Sugino, Sho Tanno, Tatsumi Yoshida, Yoshikazu Isomura, Riichiro Hira

“…The superior colliculus (SC) receives inputs from various brain regions in a layer- and radial subregion-specific manner, but whether the SC exhibits subregion-specific dynamics remains unclear. …”
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Pathogenesis of Disorders of the Motor Function of the Large Intestine in Functional Constipation by M. M. Galagudza, Yu. P. Uspensky, Yu. A. Fominykh, D. Yu. Butko

“…The main FC mechanisms associated with neurogenic dysregulation include impaired function of the gray and white matter of the brain, as well as an increase in the tone of the sympathetic nervous system with a concomitant decrease in the influence of cholinergic nerves innervating the large intestine. …”
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Silver Nanoparticles Conjugate Attenuates Highly Active Antiretroviral Therapy-Induced Hippocampal Nissl Substance and Cognitive Deficits in Diabetic Rats by Sodiq Kolawole Lawal, Samuel Oluwaseun Olojede, Ayobami Dare, Oluwaseun Samuel Faborode, Edwin Coleridge S. Naidu, Carmen Olivia Rennie, Onyemaechi Okpara Azu

“…Following the last dose of 8-week treatment, the rats were anaesthetized and euthanized. Brain tissues were carefully removed and postfixed for Nissl staining histology. …”
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Peripheral nerve injury induces dystonia-like movements and dysregulation in the energy metabolism: A multi-omics descriptive study in Thap1+/− mice by Colette Reinhold, Susanne Knorr, Rhonda L. McFleder, Lisa Harder-Rauschenberger, Tom Gräfenhan, Andreas Schlosser, Michael Sendtner, Jens Volkmann, Chi Wang Ip

“…These findings suggest that aberrant energy metabolism in brain regions relevant to dystonia may underlie the dystonic phenotype observed in nerve injured Thap1+/− mice.…”
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Feeding Problems Assessment Tools in Children: A Scoping Review by Suci Destriatania, Judhiastuty Februhartanty, Fariz Nurwidya, Rini Sekartini

“…Problems with feeding during infancy can result in significant negative consequences for a child’s nutrition, growth, and brain development. This scoping review aims to map current research, provide summary of the available feeding problem assessment tools for children, and review current implications and the gaps between tools, providing information that academics, practitioners, and parents may find useful. …”
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Feasibility and acceptability for LION, a fully remote, randomized clinical trial within the VA for light therapy to improve sleep in Veterans with and without TBI: An MTBI2 sponso... by Jonathan E Elliott, Jessica S Brewer, Allison T Keil, Brittany R Ligman, Mohini D Bryant-Ekstrand, Alisha A McBride, Katherine Powers, Savanah J Sicard, Elizabeth W Twamley, Maya E O'Neil, Andrea D Hildebrand, Thuan Nguyen, Benjamin J Morasco, Jessica M Gill, Bradley A Dengler, Miranda M Lim

“…Sleep-wake disturbances frequently present in Veterans with mild traumatic brain injury (mTBI). These TBI-related sleep impairments confer significant burden and commonly exacerbate other functional impairments. …”
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Neuropati Auditori by Sukri Rahman, Rossy Rosalinda

“…Literature Review: Auditory neuropathy is a kind of sensorineural hearing loss, in which sounds enter the inner ear normally, but the signal transmission from the inner ear to the brain is impaired in some ways. It can affect people of all ages from infant to adult. …”
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Chronic Rapamycin Prevents Electrophysiological and Morphological Alterations Produced by Conditional Pten Deletion in Mouse Cortex by Jason S. Hauptman, Joseph Antonios, Gary W. Mathern, Michael S. Levine, Carlos Cepeda

“…Abnormalities in the mammalian target of the rapamycin (mTOR) pathway have been implicated in numerous developmental brain disorders. While the molecular and histological abnormalities have been described, less is known about alterations in membrane and synaptic excitability with chronic changes in the mTOR pathway. …”
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Gender Differences in the Neurobiology of Anxiety: Focus on Adult Hippocampal Neurogenesis by Alessandra Aparecida Marques, Mário Cesar do Nascimento Bevilaqua, Alberto Morais Pinto da Fonseca, Antonio Egidio Nardi, Sandrine Thuret, Gisele Pereira Dias

“…Bridging this gap is crucial for the design of effective translational interventions in women. One of the key brain mechanisms likely to regulate anxious behavior is adult hippocampal neurogenesis (AHN). …”
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