Retinal assessment in 143 patients with white matter lesions: the potential of OCTA as an evaluation tool by Dong Zhang, Xueying Jiang, Yan Zhang, Jingcui Qin

“…BackgroundThe retina is a simple window to reflect the changes of brain nerves. The aim of this study was to investigate the association between retinal status and white matter lesions (WMLs) in 143 patients aged 50–80 years, utilizing Optical Coherence Tomography Angiography (OCTA) and the Fazekas Visual Scale for assessment.MethodsA total of 143 subjects underwent MRI scanning to assess the degree of WMLs using the Fazekas scale. …”
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Expression and prognostic value of ferritinophagy-related NCOA4 gene in low-grade glioma: integration of bioinformatics and experimental validation by Guangtang Chen, Xueping Shi, Rukai Jiao, Jiacai Qian, Xiaolin Du, Jian Liu, Xi Zeng

“…Abstract Background Low-grade glioma (LGG) is a primary brain tumor with relatively low malignancy. NCOA4 is a key regulator of ferritinophagy-related processes and is involved in the occurrence and development of many cancers. …”
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Development of a sequential laser microdissection tissue cuts workflow for the spatial and quantitative analysis of drugs in fresh frozen tissue sections. by Elias Maris, Farid Jahouh, Kathleen Allaerts, Rob Vreeken

“…The method was applied on 20μm mouse brain and liver tissue sections. The tissue cut collection yields were evaluated visually and by the detection of the sprayed standards on the tissue sections, and found to be ranging from 78% to 91%, and the throughput of the LMD cuts and collection in a 96 well format, was measured to be from 19 to 37 minutes per tissue section, depending on the 96 squares microgrid template and the corresponding magnification lens used. …”
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The Mechanism of Acupuncture Therapy for Migraine: A Systematic Review of Animal Studies on Rats by An Y, Zhang J, Ren Q, Liu J, Liu Z, Cao K

“…Yuqiu An,1,2,* Jing Zhang,1,2,* Qiaosheng Ren,1,2 Jiaojiao Liu,1,2 Zhenhong Liu,1,2,* Kegang Cao1,2,* 1Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, People’s Republic of China; 2Institute for Brain Disorders, Beijing University of Chinese Medicine, Beijing, 100700, People’s Republic of China*These authors contributed equally to this workCorrespondence: Kegang Cao; Zhenhong Liu, Email Kgdoctor@sina.com; lzhh0399@163.comBackground: Acupuncture has long been used for migraine treatment as it is convenient for use and has remarkable efficacy. …”
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Cortical tracking of hierarchical rhythms orchestrates the multisensory processing of biological motion by Li Shen, Shuo Li, Yuhao Tian, Ying Wang, Yi Jiang

“…However, how the human brain integrates these complex audiovisual cues based on their natural temporal correspondence remains unclear. …”
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Sleep fragmentation and hypoxaemia as key indicators of cognitive impairment in patients with obstructive sleep apnoea by Thomas Georgeson, Lacey Atkins, Alex Zahnleiter, Philip I Terrill, Eamonn Eeles, Elizabeth J Coulson, Irene Szollosi

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Effects of contralaterally controlled neuromuscular electrical stimulation on the connectivity pattern of poststroke patients with hemiplegia by ZHU Lan, SUI Youxin, WANG Qinglei, XU Sheng, SHEN Ying, GUO Chuan

“…The differences in overall FC strength and mean FC strength based on ROI level between the two groups were analyzed.ResultsCompared with the NMES group，the overall connectivity strength of brain regions was higher in the CCNMES group，and CCNMES could enhance the functional connectivity between the affected M1 and the healthy M1 in patients with upper limb hemiparesis in stroke，as well as enhance the functional connectivity between the affected PFC and the healthy M1 and S1，respectively，and the difference was significant （<italic>P</italic>&lt;0. 05）.ConclusionCCNMES triggers sensorimotor stimulation of the affected upper limb by active movement of the healthy upper limb and induces cortical functional reorganisation in stroke patients with hemiplegia.…”
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Detection of opioid growth factor in Multiple Sclerosis Patients by Khamael Abdulla Taha, Mayada N. Iqbal, Gheyath Abd Ali Shalal

“… Multiple sclerosis (MS) is a recent prevalent central nervous system disease that affects the brain and spinal cord. It is assumed that it is an intermediate immune disorder in the central nervous system and is complex with incomplete etiology. …”
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Protocolo de investigação e manejo do AVC isquêmico neonatal by Nicolas Ramos, Gustavo Barbosa David, Simone Cristina Stadnick, Stephanie Ribeiro Raitez

“…A head computed tomography revealed hypodensity in the right hemisphere, suggestive of hypoxic-ischemic injury. A brain computed tomography angiography did not reveal any signs. …”
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Unrolled Optimization via Physics-Assisted Convolutional Neural Network for MR-Based Electrical Properties Tomography: A Numerical Investigation by Sabrina Zumbo, Stefano Mandija, Ettore F. Meliado, Peter Stijnman, Thierry G. Meerbothe, Cornelis A.T. van den Berg, Tommaso Isernia, Martina T. Bevacqua

“…The network is trained and tested in silico using 2D slices of realistic brain models at 128 MHz. Results show the capability of the proposed procedure to reconstruct EPs maps with quality comparable to that of the popular Contrast Source Inversion-EPT, while significantly reducing the computational time.…”
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Which type of feedback—Positive or negative- reinforces decision recall? An EEG study by Michela Balconi, Michela Balconi, Laura Angioletti, Laura Angioletti, Roberta A. Allegretta, Roberta A. Allegretta

“…In a recall phase, participants’ accuracy (ACC), errors (ERRs), and response times (RTs) were recorded alongside EEG data to analyze brain activity patterns related to recall. Results indicate that accurately recalled decisions with positive feedback had slower RTs, suggesting an attentional bias toward positive information that could increase cognitive load during memory retrieval. …”
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Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease by Luiz Felipe Vasconcellos, João Santos Pereira, Marcelo Adachi, Denise Greca, Manuela Cruz, Ana Lara Malak, Helenice Charchat-Fichman, Mariana Spitz

“…We selected 79 PD patients and 92 controls (CO) to perform neurologic and neuropsychological evaluation. Brain MRI was performed to evaluate the following scales: Global Cortical Atrophy (GCA), Fazekas, and medial temporal atrophy (MTA). …”
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Cerebral Responses to Acupuncture at GV24 and Bilateral GB13 in Rat Models of Alzheimer’s Disease by Shaoyang Cui, Mingzhu Xu, Jianting Huang, Qing Mei Wang, Xinsheng Lai, Binbin Nie, Baoci Shan, Xun Luo, John Wong, Chunzhi Tang

“…These results demonstrated that acupuncturing at GV24 and bilateral GB13 acupoints may improve the learning and memory abilities of the AD rats, probably via altering cerebral glucose metabolism (CGM) in the hypothalamus, thalamus, and brain stem. The observed effects of acupuncture may be caused by regulating the distribution of certain kinds of neurotransmitters and enhancing synaptic plasticity.…”
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Hemolysis, Elevated Liver Enzymes, and Low Platelets, Severe Fetal Growth Restriction, Postpartum Subarachnoid Hemorrhage, and Craniotomy: A Rare Case Report and Systematic Review by Shadi Rezai, Justin Faye, Alexander Hughes, Mon-Lai Cheung, Joel R. Cohen, Judy A. Kaia, Paul N. Fuller, Cassandra E. Henderson

“…Hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome is a relatively uncommon but traumatic condition occurring in the later stage of pregnancy as a complication of severe preeclampsia or eclampsia. Prompt brain computed tomography (CT) or magnetic resonance imaging (MRI) and a multidisciplinary management approach are required to improve perinatal outcome. …”
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Expression of some circulating microRNAs as predictive biomarkers for prognosis and treatment response in glioblastoma by Elham Ali, Marwa Adel Ahmed, May A. Shawki, Lobna R. Ezz El Arab, Mohamed K. Khalifa, Menha Swellam

“…Abstract Glioblastoma multiforme (GBM) is the most prevalent, treatment-resistant, and fatal form of brain malignancy. It is characterized by genetic heterogeneity, and an infiltrative nature, and GBM treatment is highly challenging. …”
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Effect of Aromatherapy using Lavender Oil on Audio and Visual Reaction Time: A Quasi-experimental Study by Saroj Chaudhary, Manjinder Kaur, Suman Sharma, Naren Kurmi, Khushboo Shrimali, Soniya Pipliwal, Muskan Singh

“…Hence, it results in calming effect on the brain, inducing relaxation and sedation.…”
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An exploration of the increasing prevalence of chronic pain among Canadian veterans: Life After Service Studies 2016 and 2019 by Jhalok Ronjan Talukdar, Dena Zeraatkar, Andrew Thomas, Jason W. Busse

“…Respondents who completed the 2019 LASS were more likely to endorse an anxiety or related disorder, mood disorder, probable posttraumatic stress disorder, and traumatic brain injury. In our adjusted regression model, year of survey administration was not associated with chronic pain (OR = 1.08, P = 0.8); however, we found large associations with obesity class 1 (body mass index [BMI] = 30.0–34.9; OR = 3.66; 95% confidence interval [CI] 1.46–9.17; ARI 27%), obesity class 2 (BMI = 35.0–39.9; OR = 8.10; 95% CI 1.67–39.3; ARI 47%), mood disorder (OR = 3.20; 95% CI 1.49–6.88; ARI 24%), and an anxiety or related disorder (OR = 4.53; 95% CI 1.28–16.0; ARI 33%).Conclusions The increase in chronic pain among Canadian veterans from 2016 to 2019 appears confounded by increased comorbidities associated with chronic pain among responders in 2019.…”
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Epigene functional diversity: isoform usage, disordered domain content, and variable binding partners by Leroy Bondhus, Aileen A. Nava, Isabelle S. Liu, Valerie A. Arboleda

“…Conclusions Here we identify significant differences in isoform usage, disordered domain content, and variable binding partners between human epigenes and non-epigenes using various functional genomics datasets from Ensembl, ENCODE, GTEx, HPO, LINCS L1000, and BrainSpan. Our results contribute new knowledge to the growing field focused on developing targeted therapies for diseases caused by epigene mutations, such as chromatinopathies and cancers.…”
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Prevalence and patient characteristics associated with cardiovascular disease risk factor screening in UK primary care for people with severe mental illness: an electronic healthca... by Robert Stewart, Ann John, Bruce Guthrie, Joseph F Hayes, David P J Osborn, Stewart William Mercer, Elvira Bramon, Naomi Launders, Caroline Anne Jackson, Matthew H Iveson

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A Rare Case of Glioblastoma Multiforme with Osseous Metastases by Rubens Barros Costa, Ricardo Costa, Jason Kaplan, Marcelo Rocha Cruz, Hiral Shah, Maria Matsangou, Benedito Carneiro

“…We report the case of a 65-year-old male who underwent maximal safe resection for a newly diagnosed brain mass after presentation with new neurologic symptoms. …”
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