Regional cerebral oxygen saturation during initial mobilization of critically ill patients is associated with clinical outcomes: a prospective observational study by Ryota Imai, Takafumi Abe, Kentaro Iwata, Seigo Yamaguchi, Takeshi Kitai, Atsuhiro Tsubaki

“…We continuously measured rSO2 during the initial mobilization using a wearable brain near-infrared spectroscopy device. With in-hospital death as the primary endpoint, the association between rSO2 and in-hospital death was assessed in Analysis 1 to determine the rSO2 cut-off value that predicts in-hospital death. …”
Get full text

Management of Wernicke's encephalopathy in a pregnant woman at 27 weeks gestation complicated by pre-eclampsia: A case report by Amine Bensaid, Marouane Boukroute, Safae Bekkaoui, Hajar Berrichi, Abdelilah Elrhalete, Hamza Mimouni, Younes Oujidi, Houssam Bkiyar, Brahim Housni, Ahmed Mimouni

“…This case report details a 38-year-old woman at 27 weeks of gestation who developed altered consciousness, cerebellar ataxia, and hyperlactatemia following persistent vomiting. Brain MRI demonstrated characteristic bilateral abnormalities consistent with WE. …”
Get full text

Tailoring lipid management interventions to reduce inequalities in cardiovascular disease risk management in primary care for deprived communities in Northern England: a mixed-meth... by Julia L Newton, Yu Fu, Sarah Sowden, Paula Whitty, Eugene YH Tang

Get full text

Complex spatio-temporal features in meg data by Francesca Sapuppo, Elena Umana, Mattia Frasca, Manuela La Rosa, David Shannahoff-Khalsa, Luigi Fortuna, Maide Bucolo

“…Magnetoencephalography (MEG) brain signals are studied usinga method for characterizing complex nonlinear dynamics. …”
Get full text

GENOME POLITICS: STRATEGY AND TACTICS by Jonas Rubikas

“…Human mental and consciousness activity, brain functions obtained by learning mask the dependence of these activities on the genome. …”
Get full text

Trail without Catheter after Transurethral Resection of Prostate: Clamp It or Not? by Vikash Talreja, Aun Ali, Summaya Saeed, Kiran Rani, Sunil Sadruddin Samnani, Farah Naz Farid, Mumtazuddin Haider

Get full text

Cerebellar metastasis from colorectal cancer: a case report by Carla E. Angulo-Rojo, Luis J. Castillo-Gaxiola, Karen Gaxiola-Gastélum, Alma M. Guadrón-Llanos, Javier A. Magaña-Gómez, Diana L. Baldenebro-Félix, Diana L. Baldenebro-Félix

“…While metastasis typically occurs in the liver, lungs, and peritoneal cavity, metastasis to the brain, particularly the cerebellum, is exceedingly rare.Case presentationThis report discusses the case of a 50-year-old woman diagnosed with mucinous adenocarcinoma of the descending colon. …”
Get full text

Antipsychotic Drugs Reverse MK801-Inhibited Cell Migration and F-actin Condensation by Modulating the Rho Signaling Pathway in B35 Cells by Yi-Chyan Chen, Fu-Ming Tsai, Mao-Liang Chen

“…MK801-induced psychotic symptoms and also the Ras homolog family member A (RhoA) expression and cell division control protein 42 (cdc42) mRNA modulation in the rat brain have been investigated. Antipsychotic drugs (APDs) have been reported to induce Rho GDP-dissociation inhibitor (RhoGDI) pathway regulation related to cytoskeleton reorganization in neuronal cells. …”
Get full text

Modeling Survival Time to Death among Stroke Patients at Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study by Bikiltu Wakuma Negasa, Teramaj Wongel Wotale, Mesfin Esayas Lelisho, Legesse Kassa Debusho, Kibrealem Sisay, Wubishet Gezimu

“…Stroke is a life-threatening condition that occurs due to impaired blood flow to brain tissues. Every year, about 15 million people worldwide suffer from a stroke, with five million of them suffering from some form of permanent physical disability. …”
Get full text

Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography by Christos Ballas, Dimitrios Sfairopoulos, Ioanna Samara, Lampros Lakkas, Olga Kardakari, Athanasios Konstantinidis, Katerina K. Naka, Lampros K. Michalis, Christos S. Katsouras

“…The elderly had higher values of D-dimer, high-sensitivity troponin I and brain natriuretic peptide (BNP). Echocardiographic differences were noted and the elderly had lower values of pulmonary vascular acceleration time, RV E/A ratio and lower tricuspid annular plane systolic excursion/pulmonary artery systolic pressure ratio. …”
Get full text

Establishment of a Nomogram for Predicting Early Death in Viral Myocarditis by Xuejun Sun, Naxin Xie, Mengling Guo, Xuelian Qiu, Hongwei Chen, Haibo Liu, Hongmu Li

“…Combined with the actual clinical situation, the heart failure (HF) (OR: 2.13, 95% CI: 2.76–5.95), electrocardiogram (ECG) (OR: 6.11, 95% CI: 1.05–8.66), pneumonia (OR: 3.62, 95% CI: 1.43–9.85), brain natriuretic peptide (BNP) (OR: 4.66, 95% CI: 3.07–24.06), and lactate dehydrogenase (LDH) (OR: 1.90, 95% CI: 0.19–9.39) were finally used to construct the nomogram. …”
Get full text

Increased Risk of Cancer in relation to Gout: A Review of Three Prospective Cohort Studies with 50,358 Subjects by Weijie Wang, Donghua Xu, Bin Wang, Shushan Yan, Xiaochen Wang, Yin Yin, Xuehao Wang, Beicheng Sun, Xiaoyang Sun

“…No such significant association between gout and the risk of breast or brain cancers was observed. Sensitivity analysis did not materially alter the pooled results. …”
Get full text

Prediction models for cognitive impairment in middle-aged patients with cerebral small vessel disease by Wei Zheng, Xiaoyan Qin, Ronghua Mu, Peng Yang, Bingqin Huang, Bingqin Huang, Zhixuan Song, Xiqi Zhu, Xiqi Zhu

“…The AUC values of the brain volume, radiomics, and combined models in the test set were 0.593, 0.843, and 0.817, respectively. …”
Get full text

A History of The Six-Year Primary Project in the Use of Yoruba as the Medium of Primary Education by Toyin Falola, Michael Oladejo Afolayan

“…Therefore, it is best for the child to be encouraged to speak both languages and experience the benefits of bilingualism and a fully developing brain. 4. Similar to #3, children who are able to speak in their native language and English (or the majority language) experience higher academic achievement throughout their life. …”
Get full text

Therapeutic effects of mirodenafil, a phosphodiesterase 5 inhibitor, on stroke models in rats by Fred Kim, Padmanabh Singh, Hyunji Jo, Tianyang Xi, Dong-Keun Song, Sae Kwang Ku, Jai Jun Choung

“…Mirodenafil is a phosphodiesterase 5 (PDE5) inhibitor with high specificity for its target and good blood-brain barrier permeability. The drug, which is currently used for treatment of erectile dysfunction, reduces Aβ and pTau levels and improves cognitive function in mouse models of Alzheimer's disease. …”
Get full text

Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants by Nathalie Grova, Henri Schroeder, Jean-Luc Olivier, Jonathan D. Turner

“…Epidemiological studies have associated environmentally persistent organic pollutant exposure to brain disorders including neuropathies, cognitive, motor, and sensory impairments; neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD); and neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). …”
Get full text

A vacuum lyophilization and bacterial tablet-based method for culture medium evaluation and potential use in probiotic products by Wen Cui, Liang Zhao, Yuwen Shi, Wei Feng, Xiao Chen, Hui Liu

“…We found that the recipe GBSS (Glycerinum, Brain Heart Infusion, Sucrose, Sodium Glutamate) showed the highest survival rate for Escherichia coli in vacuum freeze-drying. …”
Get full text

Academic Pressure and Psychological Imbalance in High School Students: Predictors of Depression via Polynomial Regression and Response Surface Analysis by Ye Y, Zhang Z, Tao Z, Liping C, Wang Y, Chen H, Li S, Chen X, Tang H, Zhou J, Zhou J

“…Yanyue Ye,1,* Zheng Zhang,1,* Zhen Tao,3 Cui Liping,2 Yuxin Wang,1 Hui Chen,1 Sihong Li,1 Xianliang Chen,1 Huajia Tang,1 Jiawei Zhou,1 Jiansong Zhou1,* 1Department of Psychiatry, the Second Xiangya Hospital of Central South University, National Center for Mental Disorders, National Clinical Research Center for Mental Disorders, Changsha, People’s Republic of China; 2Department of Psychiatry, Liuyang Brain Hospital, Liuyang, People’s Republic of China; 3Human Resources Department, Hebei Vocational University of Technology and Engineering, Hebei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jiansong Zhou, Email zhoujs2003@csu.edu.cnObjective: The purpose of this study was to explore how the congruence between academic pressure and psychological imbalance affects depressive symptoms in adolescents and to further explore grade-level differences in these effects among high school students.Methods: The study population consisted of 29,975 high school students from 20 schools in Liuyang City, Hunan Province. …”
Get full text

Hubungan ICH Score dengan Outcome Fungsional (Setelah 3 Bulan) by Fanel Putra, Meiti Frida, Basjiruddin Ahmad

“…Djamil Padang dan sudah dilakukan Brain CT Scan tanpa kontras dari tanggal 1 Juni 2014 hingga 20 Juli 2014. …”
Get full text

Pimavanserin Treatment for Parkinson’s Disease Psychosis in Clinical Practice by Khashayar Dashtipour, Fiona Gupta, Robert A. Hauser, Cherian A. Karunapuzha, John C. Morgan

“…Issues addressed include distinguishing PDP from similar symptoms caused by other disorders such as dementia, coordinating pimavanserin with other PD medications and with deep brain stimulation, adapting pimavanserin dosing for optimal benefit and tolerability, and recognizing variability of PDP symptoms due to patients’ changing life circumstances. …”
Get full text