Evaluation of vitamin B6 supplementation in Wilson’s disease patients treated with D-penicillamine by Olivier Guillaud, Alain Lachaux, Justin Mbala, Abdelouahed Belmalih, Eduardo Couchonnal Bedoya

“…Introduction Wilson’s disease (WD) is a copper metabolism disorder characterised by a progressive accumulation of this metal mainly in the liver and the brain. Treatment is based on the removal of copper operated by the chelators, among which, D-penicillamine (DP) is prescribed as a first-line treatment in most situations. …”
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Vestibular Rehabilitation as an Early Intervention in Athletes Who are Post-concussion: A Systematic Review by Gabrielle Babula, Edward Warunek, Katherine Cure, Grace Nikolski, Heather Fritz, Susan Barker

“…Search terms included “vestibular rehabilitation” or “vestibular therapy” and “concussion” or “mild traumatic brain injury” or “mTBI” and “athletes” or “sports” or “athletics” or “performance”, and “early interventions” or “therapy” or “treatment”. …”
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Mitochondrial DNA copy number as a mediator of the relationship between insulin resistance and cognitive function in patients with euthymic bipolar disorder by Tsung Han Tsai, Cheng Ying Wu, Cheng Chen Chang, Ta Tsung Lin, Chin San Liu, Po See Chen

“…Abstract Persistent cognitive challenges in bipolar disorder (BD) may be tied to insulin resistance, which crucially affects both metabolism and brain health. Additionally, mitochondrial DNA (mtDNA) copy number has emerged as an indicator of cognitive performance and response to treatment in BD. …”
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Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis by Sheryl L. Coutermarsh-Ott, John T. Doran, Caroline Campbell, Tere M. Williams, David S. Lindsay, Irving C. Allen

“…During the chronic phase of infection, caspase-11 deficiency resulted in increased neuroinflammation and tissue cyst burden in the brain. Together, our data suggest that caspase-11 functions to protect the host by enhancing inflammation during the early phase of infection in an effort to minimize disease pathogenesis during later stages of toxoplasmosis.…”
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Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo by Chien-Wei Feng, Nan-Fu Chen, Te-Fu Chan, Wu-Fu Chen

“…PTP1B inhibition also reversed 6-hydroxydopamine- (6-OHDA-) induced downregulation of phospho-cAMP response element-binding protein (p-CREB) and brain-derived neurotrophic factor (BDNF) in SH-SY5Y cells. …”
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Successful Treatment of Plasma Cell-Rich Acute Rejection Using Bortezomib: A Case Report by Sara Hashemi, Reut Hod-Dvorai, Rebecca Tong, Liye Suo

“…A 37-year-old woman with reflux nephropathy received a kidney transplant from a brain-dead kidney donor. The patient presented with an acute kidney injury with a serum creatinine level over 4 mg/dL 4 months after the surgery. …”
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High expression of nucleotide-binding oligomerization domain protein 1 correlates with poor prognosis and immune cell infiltration in Glioblastoma Multiforme patients by Hongyang Zhao, Beiwu Lan, Zenghui Zhao, Peining Zhu, Chong Wang, Yufei Gao

“…Overall, our findings suggest that NOD1 is a promising prognostic biomarker and is associated with immune cell infiltration in GBM, making it a potential diagnostic biomarker for this aggressive brain cancer.…”
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Characterization and comparison of fecal microbiota in horses with pituitary pars intermedia dysfunction and age‐matched controls by Wenqing Wang, Justine Gibson, Sara Horsman, Deirdre Mikkelsen, François‐René Bertin

“…These findings support the potential role of the microbiota‐gut‐brain axis in the pathogenesis of PPID.…”
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The Effects of Light-to-Moderate Alcohol Consumption on the Cognitive Function of Community Nondemented Male Elderly: A Cohort Study by Zhang Yan, Zhang Yingjie, An Na, Qiu Qi, Li Wei, Wang Wenzheng, Sun Lin, Xiao Shifu

“…Although heavy drinking is linked with impaired brain functions, the effects of light-to-moderate drinking on the cognitive function of the elderly are still controversial. …”
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Value of Perfusion CT, Transcranial Doppler Sonography, and Neurological Examination to Detect Delayed Vasospasm after Aneurysmal Subarachnoid Hemorrhage by Ekkehard Kunze, Mirko Pham, Furat Raslan, Christian Stetter, Jin-Yul Lee, Laszlo Solymosi, Ralf-Ingo Ernestus, Giles Hamilton Vince, Thomas Westermaier

“…If detected in time, delayed cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) may be treated by balloon angioplasty or chemical vasospasmolysis in order to enhance cerebral blood flow (CBF) and protect the brain from ischemic damage. This study was conceived to compare the diagnostic accuracy of detailed neurological examination, Transcranial Doppler Sonography (TCD), and Perfusion-CT (PCT) to detect angiographic vasospasm. …”
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Gut microbiota and Parkinson’s disease by Lin Wang, Ying Cui, Bingyu Han, Yitong Du, Kenish Sirajbhai Salewala, Shiya Wang, Wenlu Zhao, Hongxin Zhang, Sichen Wang, Xinran Xu, Jianpeng Ma, Yan Zhu, Houzhen Tuo, Ting Gao

“…Emerging evidence suggests that dysbiosis of the gut microbiota is associated with the pathogenesis of Parkinson’s disease (PD), a prevalent neurodegenerative disorder. The microbiota–gut–brain axis plays a crucial role in the development and progression of PD, and numerous studies have demonstrated the potential therapeutic benefits of modulations in the intestinal microbiota. …”
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ReIU: an efficient preliminary framework for Alzheimer patients based on multi-model data by Hao Jiang, Hao Jiang, Yishan Qian, Yishan Qian, Yishan Qian, Liqiang Zhang, Liqiang Zhang, Tao Jiang, Tao Jiang, Yonghang Tai, Yonghang Tai

“…The rising incidence of Alzheimer’s disease (AD) poses significant challenges to traditional diagnostic methods, which primarily rely on neuropsychological assessments and brain MRIs. The advent of deep learning in medical diagnosis opens new possibilities for early AD detection. …”
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Transcutaneous Electrical Acupoint Stimulation in Early Life Changes Synaptic Plasticity and Improves Symptoms in a Valproic Acid-Induced Rat Model of Autism by Xiaoxi Wang, Rui Ding, Yayue Song, Juan Wang, Chen Zhang, Songping Han, Jisheng Han, Rong Zhang

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Age-Related Changes in Gut Health and Behavioral Biomarkers in a Beagle Dog Population by Anna Fernández-Pinteño, Rachel Pilla, Jan Suchodolski, Emmanuelle Apper, Celina Torre, Anna Salas-Mani, Xavier Manteca

“…The gut and the gut microbiome communicate with the nervous system through the gut–brain axis via neuroimmune and neuroendocrine mechanisms. …”
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Noncanonical Roles of hα-syn (A53T) in the Pathogenesis of Parkinson’s Disease: Synaptic Pathology and Neuronal Aging by Qing-Jun Wang, An-Di Chen, Hai-Chao Chen, Dong-Xin Wang, Yi-Ting Cai, Jie Yin, Yu-Hong Jing, Li-Ping Gao

“…The motor and nonmotor symptoms of PD involve several brain regions. However, whether α-syn pathology originating from the SNc can directly lead to the pathological changes in distant cerebral regions and induce PD-related symptoms remains unclear. …”
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Estimation of the pattern of ocular manifestations, risk factors, and imaging of rhino-orbital-cerebral mucormycosis in COVID-19 patients by Rajwinder Kaur, Grace Budhiraja, Upasana Bhumbla, Manjot Kaur, Vandana Sharma, Priyanka Gupta, Ritesh Singla, Akashdeep Goel, Ekta Gupta, Priyanka Dahiya

“…Ten patients had varied intracranial extension ranging from meningitis and cavernous sinus thrombophlebitis/thrombosis to brain abscess. Conclusions: COVID-associated ROCM was very rapidly spreading and more destructive. …”
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Motor Cortex Plasticity during Unilateral Finger Movement with Mirror Visual Feedback by Hatice Kumru, Sergiu Albu, Raul Pelayo, John Rothwell, Eloy Opisso, Daniel Leon, Dolor Soler, Josep Maria Tormos

“…Plasticity is one of the most important physiological mechanisms underlying motor recovery from brain lesions. Rehabilitation methods, such as mirror visual feedback therapy, which are based on multisensory integration of motor, cognitive, and perceptual processes, are considered effective methods to induce cortical reorganization. …”
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Sensation seeking and risk adjustment: the role of reward sensitivity in dynamic risky decisions by Yin Qianlan, Chen Shou, Hou Tianya, Dong Wei, Taosheng Liu

“…We aim to dissect the neural and cognitive mechanisms underlying this interplay, thereby shedding light on the stable brain-based characteristics contributing to the observed variability in risk-taking and decision-making behaviors. …”
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Atypical Distant Metastasis of Breast Malignant Phyllodes Tumors: A Case Report and Literature Review by Tiphaine de Foucher, Hélène Roussel, Mikael Hivelin, Léa Rossi, Caroline Cornou, Anne-Sophie Bats, Myriam Deloménie, Fabrice Lécuru, Charlotte Ngô

“…Dissemination pathways are local with chest wall invasion, regional with lymph nodes metastasis, and distant, hematogenous, mostly to the lungs, bones, and brain. Distant metastasis (DM) can be synchronous or appear months to years after the diagnosis and initial management. …”
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Artery of Percheron Infarction as an Unusual Cause of Korsakoff’s Syndrome by Yongxing Zhou, Derrick Fox, Abhishek Anand, Amal Elhaj, Arushi Kapoor, Faranak Najibi, Han Kim, Roger Weir, Annapurni Jayam-Trouth

“…Although the exact pathophysiology is unknown, various studies have identified brain lesions in the thalami, mammillary bodies, and frontal cortex. …”
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