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6081
The Neuro-Inflammatory-Vascular Circuit: Evidence for a Sex-Dependent Interrelation?
Published 2020-12-01“…This newly suggested sex-dependent brain-heart interrelation was further supported by the discovery that bone marrow activity, a surrogate parameter of inflammation, represents a potential bridging link between amygdalar activity and cardiovascular pathology by fueling inflammatory processes that promote atherosclerotic disease. …”
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6082
Downregulation of an Evolutionary Young miR-1290 in an iPSC-Derived Neural Stem Cell Model of Autism Spectrum Disorder
Published 2019-01-01“…Based on our earlier published study and the observations from the data presented here, we conclude that miR-1290 regulation could play a critical role during neuronal differentiation in early brain development.…”
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6083
Advances in functional MRI research in bipolar disorder: from the perspective of mood states
Published 2024-02-01“…We first summarise the disrupted brain activation patterns and functional connectivity that have been reported in bipolar disorder, irrespective of the mood state. …”
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6084
The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis
Published 2021-01-01“…It coordinates not only the sympathetic system and vagus system but also the autonomic nervous system and neuroendocrine system to regulate inflammation and immunity; α7nAChRs are widely expressed in immune cells, neurons, and muscle cells; the activation of α7nAChRs can suppress local and systemic inflammation; the expression of α7nAChRs represents the acute or chronic inflammatory state to a certain extent; M1AChRs are mainly expressed in the advanced centers of the brain and regulate systemic inflammation; neuroinflammation of the MVZ, hypothalamus, and forebrain induced by sepsis not only leads to their dysfunctions but also underlies the regulatory dysfunction on systemic inflammation and immunity. …”
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6085
A method for siRNA-mediated knockdown of target genes in RA-induced neurogenesis using P19 cells
Published 2025-06-01“…Furthermore, this study provides a robust and reliable protocol for gene knockdown in neuronal-like cells derived from P19 cells, thereby facilitating further investigations into the intricate molecular mechanisms that govern neurogenesis, neuronal maturation, and overall brain development. • Developed a novel protocol for targeted gene knockdown in P19 cells during neuronal differentiation. • Successful silencing of the Nfe2l1 gene during neuronal differentiation, validated by western blot. • This study provides a reliable protocol for gene knockdown in neuronal differentiation, aiding functional studies of genes in neurogenesis.…”
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6086
S100A9 protein activates microglia and stimulates phagocytosis, resulting in synaptic and neuronal loss
Published 2025-03-01“…There is a large increase in S100A9 expression in the brains of patients with neurodegenerative diseases, such as Alzheimer's disease, and S100A9 has been suggested to contribute to neurodegeneration, but the mechanisms are unclear. …”
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6087
Personalised Affective Classification Through Enhanced EEG Signal Analysis
Published 2025-12-01“…Affective classification, which employs machine learning on brain signals captured from electroencephalogram (EEG), is a prevalent approach to address this issue. …”
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6088
Smartphone Household Wireless Electroencephalogram Hat
Published 2013-01-01“…Rudimentary brain machine interface has existed for the gaming industry. …”
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6089
Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia
Published 2025-02-01“…Repetitive transcranial magnetic stimulation (rTMS) is an emerging nonpharmacological therapeutic option for fibromyalgia. rTMS involves an electromagnetic coil placed on the scalp that is rapidly turned on and off to generate short magnetic pulses to the brain (2). rTMS can reduce chronic pain by triggering inhibitory neural pathways at the level of the dorsal horn of the spinal cord. …”
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6090
Application of psychobiotics in clinical treatment of mental disorders: Neurodevelopmental disorders, neurodegenerative diseases, depression and anxiety
Published 2025-01-01“…The gut microbiota influences bidirectional communication between the brain and the gastrointestinal (GI) system. Neurons in the enteric nervous system directly interact with neurotransmitters, short‐chain fatty acids (SCFAs), gut hormones, and anti‐inflammatory cytokines produced by the gut microbiota, thereby affecting signal transmission in the central nervous system. …”
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6091
A Case of Primary T-Cell Central Nervous System Lymphoma: MR Imaging and MR Spectroscopy Assessment
Published 2013-01-01“…DWI sequences and MR spectroscopy may help to differentiate CNS lymphomas from other brain lesions. In this paper, we report a case of a 23-year-old man with T-primary central nervous system lymphoma presenting with a mass in the right frontotemporal lobe. …”
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6092
New perspectives on the glymphatic system and the relationship between glymphatic system and neurodegenerative diseases
Published 2025-02-01“…The glymphatic system, through its rapid exchange mechanisms between cerebrospinal fluid (CSF) and interstitial fluid (ISF), facilitates the movement of metabolic substances within the brain, serving functions akin to those of the peripheral lymphatic system. …”
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6093
Association of Specific Leg Muscle Strength and Motor Features in Parkinson’s Disease
Published 2024-01-01“…The association between non-PIGD motor features may suggest specific vulnerability of the hip abductors as part of a proposed brain-muscle loop hypothesis in PD. Moreover, lower hip extensor strength correlated with falls, slow walking, and FoG.…”
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6094
Development of prognostic models for HER2-positive metastatic breast cancer in females: a retrospective population-based study
Published 2024-12-01“…Independent prognostic factors of BCSS and OS included: age; marital status; race; oestrogen receptor status; surgery; chemotherapy; and bone, brain, liver, and lung metastases. The C-indices for the BCSS and OS training groups were 0.707 and 0.702, respectively. …”
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6095
Antibacterial Effectiveness of Four Concentrations of the Hydroalcoholic Extract of Solanum tuberosum (Tocosh) against Streptococcus mutans ATCC 25175TM: A Comparative In Vitro Stu...
Published 2020-01-01“…S. mutans strains were cultured in brain heart infusion agar using the swab technique. …”
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6096
Parkinsonism and Sjögren’s Syndrome: A Fortuitous Association or a Shared Immunopathogenesis?
Published 2015-01-01“…A 46-year-old woman with a history of progressive Parkinsonism for 6 years and a normal brain magnetic resonance imaging was partially improved with levodopa therapy. …”
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6097
Management of Traumatic Pancreatic Injuries: Evaluation of 7 Years of Experience at a Single Regional Trauma Center
Published 2021-09-01“…The overall in-hospital mortality rate was 24% (n=11), and only one patient died after NOM (due to a severe traumatic brain injury). Twenty-two patients (79%) underwent emergency laparotomy and six (21%) underwent delayed laparotomy. …”
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6098
A generative model for evaluating missing data methods in large epidemiological cohorts
Published 2025-02-01“…Results On the UK Biobank brain imaging cohort, we identify several large blocks of missing data. …”
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6099
Mitotic block and epigenetic repression underlie neurodevelopmental defects and neurobehavioral deficits in congenital heart disease
Published 2025-01-01“…Adult mice harboring either the Pcdha9 mutation, which show normal brain anatomy, or forebrain-specific Sap130 deletion via Emx1-Cre, which show microcephaly, both demonstrate learning and memory deficits and autism-like behavior. …”
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6100
Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation
Published 2016-01-01“…Computed tomography (CT) showed no lesion and CT perfusion study evidenced oligohemia in left hemisphere. A normal brain magnetic resonance (MR) was obtained. Impaired consciousness and dysphasia began to improve three days after admission and mild dysphasia and right hemiparesis lasted for 10 days. …”
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