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5421
Inherited Paediatric Motor Neuron Disorders: Beyond Spinal Muscular Atrophy
Published 2017-01-01“…Paediatric motor neuron diseases encompass a group of neurodegenerative diseases characterised by the onset of muscle weakness and atrophy before the age of 18 years, attributable to motor neuron loss across various neuronal networks in the brain and spinal cord. While the genetic underpinnings are diverse, advances in next generation sequencing have transformed diagnostic paradigms. …”
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5422
Targeting Mitochondrial Dysfunction in Cerebral Ischemia: Advances in Pharmacological Interventions
Published 2025-01-01“…Disruptions in mitochondrial function, driven by factors such as oxidative stress, excitotoxicity, and altered ion balance, lead to neuronal death and contribute to cognitive impairments in several brain diseases. Mitochondrial dysfunction can arise from genetic mutations, ischemic events, hypoxia, and other environmental factors. …”
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5423
Multimodal Opera Performance Form Based on Human-Computer Interaction Technology
Published 2022-01-01“…With little audience involvement, theatre performing arts like opera typically have difficulty keeping audiences’ attention. The brain-computer interaction (BCI) technology could be used in opera performances to alter the audience’s emotional experience. …”
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5424
Case Report of RANBP2 Mutation and Familial Acute Necrotizing Encephalopathy
Published 2021-01-01“…Unlike the siblings, the cousin eventually expired mainly due to the delay in diagnosis, resulting from late presentation of typical brain involvements of ANE in magnetic resonance imaging (MRI). …”
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5425
The Development of Alternative Dosage Form for Creatine Monohydrate: A Floating Tablet
Published 2023-12-01“…Creatine monohydrate has been developed as a neuroprotective agent and can penetrate in vitro model of the blood-brain barrier. However, its delivery is hampered by its limited capacity of creatine transporter. …”
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5426
The Impact of Early Neuroimaging and Developmental Assessment in a Preterm Infant Diagnosed with Cerebral Palsy
Published 2019-01-01“…At term, anatomical MRI showed bilateral periventricular leukomalacia, abnormal brain metabolites in frontal white matter via MR spectroscopy (MRS), and low fractional anisotropy (FA) values obtained from diffusional kurtosis imaging (DKI) in several cortical white matter tracts compared to a group of typically developing infants without neuroimaging abnormalities. …”
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5427
An Emerging New Paradigm in Opioid Withdrawal: A Critical Role for Glia-Neuron Signaling in the Periaqueductal Gray
Published 2012-01-01“…., semisynthetic derivatives of opium and other molecules that activate opioid receptors) induces dependence, which is associated with various specific behavioral and somatic signs after their withdrawal or after the administration of an opioid antagonist. Among the brain regions implicated in opiate dependence and withdrawal, the periaqueductal gray area (PAG) appears to be critical in regulating the complex signs and symptoms of opioid withdrawal. …”
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5428
The Default Mode Network and Altered Consciousness in Epilepsy
Published 2011-01-01“…The default mode network has been hypothesized based on the observation that specific regions of the brain are consistently activated during the resting state and deactivated during engagement with task. …”
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5429
Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos.
Published 2025-01-01“…Secondly, the endogenous mRNA levels of DrPGRP-5 were highly expressed in brain and muscle while significantly down-regulated in liver and egg at 72 hpf in zebrafish embryos. …”
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5430
Effect of Glycine on Lead Mobilization, Lead-Induced Oxidative Stress, and Hepatic Toxicity in Rats
Published 2011-01-01“…The effect of these treatments on parameters indicative of oxidative stress (glutathione and malondialdehyde levels), the activity of blood 𝛿-aminolevulinic acid dehydratase, and lead concentration in blood, liver, kidney, brain, and bone were investigated. Liver samples were observed for histopathological changes. …”
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5431
The effect of infra low frequency–neurofeedback training on pistol shooting performance and attention in semi-skilled players
Published 2025-01-01“…PurposeNeurofeedback (NF) typically involves an operant conditioning or other reinforcement protocol aimed at self-regulating patterns of brain activation. Endogenous Neuromodulation, characterized by the absence of discrete reinforcers, has emerged over the last two decades with the extension of training into the infra-low frequency regime, i.e., below 0.1 Hz. …”
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5432
Health promotion for dementia risk reduction in Indigenous populations of Canada, Aotearoa New Zealand, United States of America, and Australia: Scoping review protocol.
Published 2024-01-01“…Dementia, a collective name for brain disorders that impact thinking and memory, affects over 55 million people worldwide. …”
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5433
Medical foods in Alzheimer’s disease
Published 2019-03-01“…Improvements in symptomatology and regional brain atrophy in AD have been claimed for several medical foods, for example, those providing ketone bodies as alternative energy supply to neurons, those containing precursors believed to improve synaptic function, and those addressing oxidative stress related to memory loss. …”
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5434
The Use of Antisense-Mediated Inhibition to Delineate The Role of Inflammatory Agents in The Pathophysiology of Spinal Cord Injury
Published 2002-01-01“…During this period, glia and immune cells respond to chemical cues associated with the debris of lysed neurons, disrupted axons, and a broken blood-brain-barrier by releasing a battery of cytokines including tumor necrosis factor-α (TNF-α) and, interleukin-β (IL-1β) as well as reactive oxygen species such as nitric oxide (NO-)[2]. …”
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5435
High-Performance Wireless Piezoelectric Sensor Network for Distributed Structural Health Monitoring
Published 2016-03-01“…In addition to hardware, embedded signal processing and distributed data processing algorithm are designed as the intelligent “brain” of the proposed wireless monitoring network to extract features of the PZT signals, so that the data transmitted over the wireless link can be reduced significantly.…”
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5436
Functional Connectivity Pattern Analysis Underlying Neural Oscillation Synchronization during Deception
Published 2019-01-01“…To characterize system cognitive processes during deception, event-related coherence was computed to investigate the functional connectivity among brain regions underlying neural oscillation synchronization. …”
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5437
Production of Toxic Volatile Trimethylbismuth by the Intestinal Microbiota of Mice
Published 2011-01-01“…Concomitantly, a higher bismuth concentration was found in organs such as liver, lung, testicles, and brain of the CONV mice as compared to those of GF mice (P>0.01), strongly suggesting a correlation between the intestinal biomethylation of bismuth and its accumulation in mammalian tissues.…”
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5438
Systemic Amyloidosis and Cardiac Autonomic Neuropathy Associated with Waldenstrom’s Macroglobulinemia
Published 2017-01-01“…EKG, 24-hour Holter monitoring, and 2D echocardiogram were unremarkable. MRI of the brain ruled out stroke. Patients with amyloidosis can develop cardiovascular disease through amyloid cardiomyopathy, small vessel disease, conduction defects, pericardial effusion, or autonomic denervation. …”
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5439
Suboptimal but intact integration of Bayesian components during perceptual decision-making in autism
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5440
Interoception, cardiac health, and heart failure: The potential for artificial intelligence (AI)—driven diagnosis and treatment
Published 2025-01-01“…This phenomenon is known as “interoception” and refers to the sensing and interpretation of internal body signals, allowing the brain to communicate with various body systems. Dysfunction in interoception is associated with cardiovascular disorders. …”
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