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5161
Pre-editing rules developed for higher-quality target language texts
Published 2024-12-01“…Neural machine translation (NMT/MT) has recently developed by leaps and bounds through deeply learning human brain mechanism, and its effective use has been the focus of much attention. …”
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5162
Central and nephrogenic diabetes insipidus: updates on diagnosis and management
Published 2025-01-01“…The main branchpoints in pathophysiology depend on the level of ADH pathology: the brain or the kidneys. Prompt diagnosis and treatment are critical as DI can cause substantial morbidity and mortality. …”
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5163
Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases
Published 2012-01-01“…Amyotrophic lateral sclerosis (ALS) is a heterogeneous group of incurable motor neuron diseases (MNDs) characterized by a selective loss of upper and lower motor neurons in the brain and spinal cord. Most cases of ALS are sporadic, while approximately 5–10% cases are familial. …”
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5164
Deep learning to decode sites of RNA translation in normal and cancerous tissues
Published 2025-02-01“…We demonstrate that RiboTIE successfully recapitulates known findings and provides novel insights into the regulation of RNA translation in both normal brain and medulloblastoma cancer samples. Our results suggest that RiboTIE is a versatile tool that can significantly improve the accuracy and depth of Ribo-Seq data analysis, thereby advancing our understanding of protein synthesis and its implications in disease.…”
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5165
Viral Vector Induction of CREB Expression in the Periaqueductal Gray Induces a Predator Stress-Like Pattern of Changes in pCREB Expression, Neuroplasticity, and Anxiety in Rodents
Published 2009-01-01“…The findings of this study suggest that by increasing CREB and pCREB in the right lateral PAG, it is possible to produce rats that exhibit behavioral, brain, and molecular changes that closely resemble those seen in predator stressed rats.…”
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5166
A study to determine the effect of nano-selenium and thymoquinone on the Nrf2 gene expression in Alzheimer’s disease
Published 2025-12-01“…The levels of Nrf2 in brain tissues were evaluated using real-time PCR.Results Nrf2 mean expression levels in the nano-selenium-treated rats, the thymoquinone-treated rats, and the rats that were given both treatments all increased significantly compared to AD rats with no treatment.Conclusions This study showed that nano-selenium and thymoquinone elevated Nrf2 gene expression levels in AD.…”
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5167
Lumbar Intraspinal Osteolipoma Presenting as Cauda Equina Syndrome: A Case Report and Review of Literature
Published 2018-01-01“…These lesions have been usually reported to arise from the oral cavity, brain, and neck and scarcely from the knee and thigh. …”
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5168
Stress-Induced Changes in the Gastrointestinal Motor System
Published 1999-01-01“…In animals, the most consistent findings include retardation of gastric emptying in response to various stressors; acceleration of gastric emptying upon cold stress, presumably through the secretion of brain thyroglobulin-hormone; acceleration of intestinal transit; and stimulation of colonic transit and fecal output. …”
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5169
An Intracranial Extradural Dermoid Cyst Presenting with Two Dermal Sinuses and an Abscess in a Child
Published 2021-01-01“…Herein, we report a rare case of a 1-year-old female presenting with a midline, scalp abscess. Brain MRI revealed an intracranial, extradural tumor, with features suggestive of a dermoid cyst, unusually located in the crista galli, and complicated by the formation of two cutaneous sinus tracts. …”
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5170
Neurogranin in Alzheimer's Disease: Roles in synaptic function, pathology, and potential as a diagnostic biomarker
Published 2024-09-01“…This review, therefore, looked at the functionality of Ng in the brain, its association with other synaptic proteins, and its applicability as a diagnostic marker in AD. …”
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5171
Early growth response 1 transcription factor and its context-dependent functions in glioblastoma
Published 2024-08-01“…Glioblastoma is the most aggressive form of primary brain tumour in adults. This tumour employs numerous transcription factors to advance and sustain its progression. …”
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5172
Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity
Published 2016-01-01“…A pathological hallmark of Parkinson’s disease (PD) is formation of Lewy bodies in neurons of the brain. This has been attributed to the spread of α-synuclein (α-syn) aggregates, which involves release of α-syn from a neuron and its reuptake by a neighboring neuron. …”
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5173
Comprehensive Insight of Neurodegenerative Diseases and The Role of Neurotoxin Agents — Glutamate
Published 2020-04-01“…GSH plays an important role in the disposal of peroxides by brain cells and in the protection against ROS. Depletion of GSH renders the cell to oxidative stress and ultimately leading to cell death. …”
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5174
A disproportionality analysis of FDA adverse event reporting system events for misoprostol
Published 2025-01-01“…Although most AEs complied with the drug instruction, new AEs signals such as congenital aqueductal stenosis and congenital brain damage were also identified. Clinicians should make appropriate evaluation when using misoprostol, closely monitor the indicators of patients, and have appropriate countermeasures for possible adverse events.…”
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5175
Attentional Phenotypes for the Analysis of Higher Mental Function
Published 2002-01-01“…We outline a strategy to relate normal cognitive processes to candidate genes. First, brain imaging is used to specify a cognitive process “attention” in terms of the neural networks involved. …”
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5177
Bipolar Disorder and Multiple Sclerosis: A Case Series
Published 2014-01-01“…MRI lesions suggest the possible implication of local MS-related brain damage in development of pure “psychiatric fits” in MS. …”
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5178
Metrics of Phenomenological Virtual Experience
Published 2024-12-01“…The author highlights the field interference of the real and the virtual, the superposition of real and virtual components in the perception of virtual reality by humans, combined by the human brain into a single perception. The result of the study is a constructed model of probabilistic dependencies between elements of immersion and metrics of phenomenological experience. …”
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5179
Lactoferrin alleviates the adverse effects of early-life inflammation on depression in adults by regulating the activation of microglia
Published 2025-02-01“…Abstract Lactation is a crucial phase of brain development, and the events and nutrients during this period have long-term consequences for the occurrence of depression. …”
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5180
Neuroprotective effects of arbutin against oxygen and glucose deprivation-induced oxidative stress and neuroinflammation in rat cortical neurons
Published 2022-03-01“…The anti-ischemic activity of arbutin can arrest post-stroke damage to the brain.…”
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