Case report: Discovery of novel CTNNB1 mutations and comparison of clinical characteristics in two patients with NEDSDV by Eojin Lee, Ja Young Choi, Shin-Seung Yang

“…NGS is crucial for the diagnosis of global developmental delay, particularly when brain magnetic resonance imaging (MRI) results appear normal. …”
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STRUCTURAL AND DYNAMIC PROPERTIES OF MUTANTS OF THE SOD1 PROTEIN ASSOCIATED WITH AMYOTROPHIC LATERAL SCLEROSIS by N. A. Alemasov, N. V. Ivanisenko, V. A. Ivanisenko

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, which affects motor neurons in the brain and spinal cord and leads to patients’ death. …”
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Current Status of Plant-Based Bioactive Compounds as Therapeutics in Alzheimer’s Diseases by Dan Chen, Yun Sun

“…Numerous studies have shown that medicinal plants and their active ingredients can potentially mitigate AD by regulating various molecular mechanisms, including the production and aggregation of pathological proteins, oxidative stress, neuroinflammation, apoptosis, mitochondrial dysfunction, neurogenesis, neurotransmission, and the brain-gut microbiota axis. In this review, we analyzed the pathogenesis of AD and comprehensively summarized recent advancements in research on medicinal plants for the treatment of AD, along with their underlying mechanisms and clinical evidence. …”
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Successful Treatment of Posttransplant EBV-Associated Lymphoma and Plasmacytoma Solely Localized to the CNS by Per Boye Hansen, Signe Ledou Nielsen

“…The histological diagnoses of the isolated brain tumors were diffuse large B-cell lymphoma and plasmacytoma. …”
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Circuitry and Synaptic Dysfunction in Alzheimer’s Disease: A New Tau Hypothesis by Siddhartha Mondragón-Rodríguez, Humberto Salgado-Burgos, Fernando Peña-Ortega

“…Additionally, we will briefly address the role of brain circuit alterations as a potential biomarker for detecting the prodromal AD stage.…”
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Induced pluripotent stem cell–related approaches to generate dopaminergic neurons for Parkinson’s disease by Ling-Xiao Yi, Hui Ren Woon, Genevieve Saw, Li Zeng, Eng King Tan, Zhi Dong Zhou

“…The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson’s disease, the second most common human neurodegenerative disease. …”
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Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain by Geeta Ramesh, Andrew G. MacLean, Mario T. Philipp

“…This review will focus on how cytokines and chemokines affect neuroinflammation and disease pathogenesis in bacterial meningitis and brain abscesses, Lyme neuroborreliosis, human immunodeficiency virus encephalitis, and neuropathic pain.…”
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The Smoothing Artifact of Spatially Constrained Canonical Correlation Analysis in Functional MRI by Dietmar Cordes, Mingwu Jin, Tim Curran, Rajesh Nandy

“…A wide range of studies show the capacity of multivariate statistical methods for fMRI to improve mapping of brain activations in a noisy environment. An advanced method uses local canonical correlation analysis (CCA) to encompass a group of neighboring voxels instead of looking at the single voxel time course. …”
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Neuroplasticity in Alzheimer's disease: a therapeutic alternative at the molecular level by Noel Jesús Niebla Gómez, Rodolfo Javier Rivero Morey, Víctor René Navarro Machado, Mariangel González León, Amanda Martínez Pérez

“…It was concluded that, according to the strongest evidence found, the fundamental therapeutic alternatives are those focused on enhancing neuronal plasticity; standing out within this group of therapies, physical exercise, transcranial magnetic stimulation and increased concentrations of brain-derived neurotrophic factor. Especially notable the repetitive transcranial magnetic stimulation, due to its demonstrated ability to promote neuronal plasticity through different ways.…”
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Reconstitution de gestes funéraires by David Peressinotto, Bruno Maureille, Yves Lecointe, Francis Geus

“…At the opposite, the very dry climate of the Middle Nubia can explain by itself the exceptional conservation of soft parts of the human body (hair, nails, brain, muscular fibres, human coprolithes) as it is frequently found at the North necropolis (SN) of the Saï island (Northern Province, Sudan). …”
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Arv1; a “Mover and Shaker” of Subcellular Lipids by J. Jose Corbalan, Karla K. Frietze, Joseph Nickels, Stephen L. Sturley

“…Murine in vivo studies point to a role for ARV1 in regulating obesity, glucose tolerance, insulin sensitivity and brain function. Multiple human ARV1 variants have been associated with epileptic encephalopathy, cerebellar ataxia, and severe intellectual deficits. …”
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Homonymous Superior Quadrantanopia due to Erdheim-Chester Disease with Asymptomatic Pituitary Involvement by Roaa Ridha Amer, Sara Mohammed Qubaiban, Eman Abdulkarim Bakhsh

“…Plain X-ray of both knees showed bilateral patchy sclerosis of the distal femur and upper parts of the tibiae. Initial brain magnetic resonance imaging (MRI) showed bilateral enhancing masses in the temporal lobes anterior to the temporal horns, thickening of the pituitary stalk, partially empty sella, and involvement of the left cavernous sinus one year later. …”
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Primary Angiitis of the Central Nervous System: A Report of Three Cases from a Single Colombian Center by Nicolás Coronel-Restrepo, Fabio Bonilla-Abadía, Omar A. Cortes, Jorge H. Izquierdo, Alberto M. Shinchi, Juan C. Bravo, Gabriel J. Tobón, Carlos A. Cañas

“…Its clinical manifestations are very heterogeneous and make clinical diagnosis difficult. In most cases, a brain biopsy is required. Only the clinical suspicion and the ability to recognize the possible clinical and imagenological patterns of presentation make an accurate diagnosis possible. …”
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Dissociative Experiences Scale: Psychometric Analysis in Puerto Rico and Contributions to the Discussion of the Factor Structure by Juan González-Rivera

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Mice with Catalytically Inactive Cathepsin A Display Neurobehavioral Alterations by O. Y. Calhan, V. Seyrantepe

“…These patients present with a broad range of clinical phenotypes, including growth retardation, and neurological deterioration along with the accumulation of the vasoactive peptide, endothelin-1, in the brain. Previous in vitro studies have shown that CathA has specific activity against vasoactive peptides and neuropeptides, including endothelin-1 and oxytocin. …”
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Hyperammonemia: What Urea-lly Need to Know: Case Report of Severe Noncirrhotic Hyperammonemic Encephalopathy and Review of the Literature by Ruby Upadhyay, Thomas P. Bleck, Katharina M. Busl

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The Rise of Pluripotent Stem Cell-Derived Glia Models of Neuroinflammation by Srishti Kala, Andrew G. Strutz, Moriah E. Katt

“…Neuroinflammation has been implicated in nearly every major CNS disease ranging from Alzheimer’s disease to brain cancer. Understanding and modeling neuroinflammation is critical for the identification of novel therapeutic targets in the treatment of CNS diseases. …”
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Evaluation of the Neuroprotective Effect of Lawsonia inermis Flower Extract in Alzheimer’s Disease-induced Zebrafish Model by Kavitha Ramasamy, K. Priya Gayathri, Binoy Varghese Cheriyan, I. Glory Josephine, V. D. Deepti

“…Results: In Phase I, a dose-dependent reduction of degeneration was observed in the pathology of the brain with no significant changes in cognition. In Phase II, the effective dose (8 μg/day/0.5 mg fish) of L. inermis flower extract has shown a significant reduction in anxiety, degeneration, and motor dysfunction with a significant increase in memory and learning. …”
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The Effect of The Mind Map Method on The Students’ Memory in Thematic Learning by Dea Amelia Harits, Mizaniya Mizaniya

“…Mind mapping is a method that can optimize students' memory, because it uses images, lines, colors, and symbols that can stimulate the child's double senses, in addition mind mapping can also maximize their brain abilities. The purpose of this study was to find out the influence of mind map method on the memory of learners in thematic learning in class IV MI Ma'arif NU 02 Tamansari. …”
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Imatinib-resistance without BCR/ABL Point Mutation in Chronic Myeloid Leukemia by Aytan Shirinova

“…In the future, new molecules for BCR-ABL inhibitors, combination therapy, and molecules entering the blood-brain barrier may improve the outcomes of therapy and prevent imatinib resistance in CML.…”
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