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4661
Protocol for microinjection of rapamycin into the zebrafish habenula
Published 2025-03-01“…Summary: Mechanistic target of rapamycin complex 1 (mTorC1) activity plays a crucial role in brain development. Here, we present an approach for rapamycin microinjection into the habenula of larval zebrafish to achieve localized inhibition of the mTorC1 pathway and explore the role of mTorC1 in habenula function. …”
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4662
in vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes
Published 2007-01-01“…The extract was also studied for lipid peroxidation assay by thiobarbituric acid–reactive substances (TBARS) using young and aged rat brain mitochondria. The extract was also effective in preventing mitochondrial lipid peroxidation induced by FeSO4/ ascorbate in concentration dependent manner. …”
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4663
Magnetic Resonance Imaging Lesions in the Central Nervous System of a Dog with Canine Monocytic Ehrlichiosis
Published 2011-01-01“…On magnetic resonance imaging (MRI), there were multifocal, punctate, T2-hyperintense lesions in the brain and cervical spinal cord and intracranial leptomeningeal contrast enhancement. …”
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4664
A Case Report of Leptomeningeal Myelomatosis and Rapid Improvement with Regimen Consisting of Daratumumab, Pomalidomide, Vincristine, Procarbazine, and Dexamethasone
Published 2022-01-01“…Central nervous system (CNS) involvement in multiple myeloma (MM) (MM-CNS) in the form of leptomeningeal myelomatosis or brain parenchyma plasmacytoma is rare, causing challenges in clinical diagnosis and treatment. …”
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4665
Muscle Memory and the Development of Speaking Skills: Unveiling Neuromotor Foundations and Methodological Approaches in Foreign Language Education
Published 2024-01-01“…It sheds light on its roots – the main muscles and brain areas involved – as well as its role in verbal communication, articulation, and language acquisition in general. …”
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4666
Towards transformative innovation ecosystems: a systemic approach to responsible innovation
Published 2024-12-01“…The concept is developed by bringing theoretical perspectives into conversation with empirical insights from the high-tech research and innovation cluster NeuroSys, which aims to create an ecosystem around brain-inspired computing.…”
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4667
The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways
Published 2020-01-01“…Ras analog in brain (Rab) proteins are small guanosine triphosphatases (GTPases) that belong to the Ras-like GTPase superfamily, and they can regulate vesicle trafficking. …”
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4668
Case report: Development of anxiety symptoms after receiving the Pfizer-BioNTech (BNT162b2) COVID-19 vaccine: a case series
Published 2025-01-01“…The clinical manifestations of long COVID include depression, anxiety, brain fog with cognitive dysfunction, memory issues, and fatigue. …”
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4669
The Influence of Electrode Impedance on the Parameters of Visual Evoked Potentials
Published 2025-01-01“…For recording spontaneous activity of the brain (EEG), two types of reusable electrodes should be considered, i.e., cup (Au, Ag, Ag/AgCl) and sintered bridge electrodes (SBEs) with a gold or silver pin. …”
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4670
Psychosis of Epilepsy: An Update on Clinical Classification and Mechanism
Published 2025-01-01“…Additionally, we examine the potential pathophysiological mechanisms underlying the psychosis of epilepsy from three perspectives: neuroimaging, neurobiology, and genetics. The alterations in brain structure and function, neurotransmitters, neuroinflammatory mediators, and genetic factors discussed in this review may offer insights into the onset and progression of psychotic symptoms in epilepsy patients and are anticipated to inform the identification of novel therapeutic targets in the future.…”
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4671
On the Inverse EEG Problem for a 1D Current Distribution
Published 2014-01-01“…The immediate representation of this problem refers to the inverse problem of electroencephalography (EEG) with a linear current distribution and the spherical model of the brain-head system. It is shown that the support is identified through the solution of a nonlinear algebraic system which is investigated thoroughly. …”
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4672
A History of Research on Human Evolution in South Africa from 1924 to 2016
Published 2017-01-01“…The pioneering work was continued by Bob Brain, Elisabeth Vrba, Phillip Tobias, Ron Clarke, Francis Thackeray and their teams. …”
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4673
Mapping the Consequences – An Exploratory Study on the Use of Body Mapping Technique to Assess Perceptions of Health-care Workers on the Effects of Uncontrolled Diabetes Mellitus a...
Published 2024-04-01“…Fourteen (74%) participants had mapped kidneys and 11 (58%) participants had mapped head/brain indicating stroke to indicate damage due to uncontrolled diabetes mellitus and hypertension. …”
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4674
Misleading Rare Case of Idiopathic Hypertrophic Pachymeningitis
Published 2024-01-01“…MRI identified diffuse nodular dural thickening with internal septations and different internal hemorrhagic stages on the right side with no evidence of brain parenchymal involvement and according to the serology and autoimmune screening tests, and IHP was diagnosed for the patient. …”
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4675
Utilisation of High Molecular Weight and Ultra-High Molecular Weight Hyaluronan in Management of Glioblastoma
Published 2025-01-01“…Considering the limited treatment options available in the treatment of glioblastoma, in this review, we discuss the novel utilisation of ultra-high molecular weight HA—originally identified as a mechanism for maintaining longevity in the naked mole-rat—as both a protective and extracellular matrix-optimizing colloidal scaffold, and a means to deliver therapy in resected brain tumours. The unique properties of this unique form of HA cross-linked gel indicate potential future use in the prevention and treatment of both proliferative-based and inflammation-driven disease.…”
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4676
Vestibular schwannoma: evolution of diagnosis and treatment
Published 2025-01-01“…While there is no infiltration or invasion of brain tissue, the tumors are still dangerous lesions because of their position in the cerebellopontine angle and potential for compression in a crowded neighborhood filled with vital structures. …”
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4677
A case of cutaneous melanoma metastatic to the ciliary body and choroid with complete regression via systemic dual checkpoint inhibitor therapy
Published 2025-01-01“…Abstract Background Cutaneous melanoma is the leading cause of death from cutaneous malignancy and tends to metastasize lymphatically and hematogenously to the lung, liver, brain, and bone; it is a rare source of metastatic disease to the eye. …”
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4678
Orbital Cellulitis: A Rare Presentation of Metastatic Bronchial Carcinoma
Published 2011-01-01“…Further imaging revealed a large, asymptomatic, bronchial primary with deposits in the brain and liver. The advanced presentation of the disease limited treatment to best supportive care. …”
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4679
Immune Privilege as an Intrinsic CNS Property: Astrocytes Protect the CNS against T-Cell-Mediated Neuroinflammation
Published 2013-01-01“…They are responsible for formation of the blood-brain barrier (BBB) and make up the glia limitans. …”
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4680
Neurological and Neurobehavioral Disorders Associated with Toxoplasma gondii Infection in Humans
Published 2021-01-01“…The intracellular parasite Toxoplasma gondii is estimated to infect up to 30% of the world population, leading to lifelong chronic infection of the brain and muscle tissue. Although most latent T. gondii infections in humans have traditionally been considered asymptomatic, studies in rodents suggest phenotypic neurological changes are possible. …”
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