A narrative review about cognitive impairment in Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD): Another matter to face through a holistic approach by Marica Meroni, Miriam Longo, Erika Paolini, Paola Dongiovanni

“…All these conditions contribute to a chronic inflammatory status which may impact on blood brain barrier (BBB) integrity leading to an impaired function of central nervous system (CNS). …”
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Gastrodin Suppresses the Amyloid β-Induced Increase of Spontaneous Discharge in the Entorhinal Cortex of Rats by Peng-zhi Chen, Hui-hui Jiang, Bo Wen, Shuan-cheng Ren, Yang Chen, Wei-gang Ji, Bo Hu, Jun Zhang, Fenglian Xu, Zhi-ru Zhu

“…The entorhinal cortex (EC) is one of the earliest affected brain regions in AD. Impairments of EC neurons are responsible for the cognitive deficits in AD. …”
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Hemophagocytic Syndrome-Associated Variant of Methotrexate-Associated Intravascular Large B-Cell Lymphoma in a Rheumatoid Arthritis Patient by Yukiko Komeno, Minako Akiyama, Yasumi Okochi, Hitoshi Tokuda, Keiko Abe, Kuniko Iihara, Tomiko Ryu

“…Although salvage chemotherapy (CHASER), whole brain irradiation, and intrathecal injection of cytarabine and prednisolone were temporarily effective, he died. …”
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Can Radiomics of Dynamic PET Imaging with 11C-methionine Predict EGFR Amplification Status in Glioblastoma? by Gleb DANILOV, Andrey POSTNOV, Diana KALAEVA, Nina VIKHROVA, Tatyana KOBYAKOVA

“… Introduction: Epidermal growth factor receptor (EGFR) amplification predicts poor survival in patients with brain gliomas. Purpose: This study aimed to evaluate whether EGFR amplification status can be predicted using radiomics data from dynamic PET scanning with 11C-methionine. …”
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Genomics Analysis of Metabolic Pathways of Human Stem Cell-Derived Microglia-Like Cells and the Integrated Cortical Spheroids by Julie Bejoy, Xuegang Yuan, Liqing Song, Thien Hua, Richard Jeske, Sébastien Sart, Qing-Xiang Amy Sang, Yan Li

“…Brain spheroids or organoids derived from human pluripotent stem cells (hiPSCs) are still not capable of completely recapitulating in vivo human brain tissue, and one of the limitations is lack of microglia. …”
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RETRACTED: Associations of vitamin D receptor polymorphisms with risk of Alzheimer’s disease, Parkinson’s disease, and mild cognitive impairment: a systematic review and meta-analy... by Yanjun Du, Peizhen Geng, Qunqun Chen, Laixi Han, Lu Liu, Maoquan Yang, Mingzhu Tan, Jun Meng, Xiaojuan Sun, Lidan Feng

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Examining Internal and External Consent in Consensual and Non-Consensual Contexts in Women by Nieves Moyano, Antonio Rafael Hidalgo-Muñoz, María del Mar Sánchez-Fuentes, Kristen Jozkowski, Reina Granados

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CaGe: A Web-Based Cancer Gene Annotation System for Cancer Genomics by Young-Kyu Park, Tae-Wook Kang, Su-Jin Baek, Kwon-Il Kim, Seon-Young Kim, Doheon Lee, Yong Sung Kim

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A concise practical clinical guide to identifying spasticity in neurological shoulder dysfunction by Damon Hoad, Stephen Ashford, Stephen Ashford, Ganesh Bavikatte, Rachel Farrell, Rachel Farrell, Adrian Robertson, Jörg Wissel, Jörg Wissel

“…BackgroundSpasticity is a known complication to the hemiplegic shoulder following acquired brain injury. However, there is a current discrepancy between the diagnosis of arm spasticity and the subsequent assessment and treatment of spasticity in people with shoulder involvement.ObjectiveAn expert panel aimed to establish a consensus and provide a simple structured approach to identifying and assessing people with spasticity of the hemiplegic shoulder.MethodsA consensus group of six spasticity experts were interviewed individually via 1-h video calls to ascertain how they assess people with arm spasticity for shoulder involvement. …”
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Pharmacological enhancement of slow-wave activity at an early disease stage improves cognition and reduces amyloid pathology in a mouse model of Alzheimer’s disease by Sedef Kollarik, Sedef Kollarik, Sedef Kollarik, Dorita Bimbiryte, Aakriti Sethi, Inês Dias, Inês Dias, Inês Dias, Carlos G. Moreira, Daniela Noain, Daniela Noain, Daniela Noain, Daniela Noain

“…Histochemical assessment of amyloid plaques demonstrated that SO-treated 11-month-old Tg2576 mice had significantly less plaque burden than placebo-treated ones, whereas ELISA of insoluble protein fractions from brains of 6-month-old Tg2576 mice indicated lower Aβ-42/Aβ-40 ratio in SO-treated group vs. placebo-treated controls.DiscussionAltogether, our results suggest that SWA-dependent reduction in brain amyloidosis leads to alleviated behavioral impairment in Tg2576 mice only if administered early in the disease course, potentially highlighting the key importance of early sleep-based interventions in clinical cohorts.…”
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Neurofilament light chain levels in neuronal surface antibody-associated autoimmune encephalitis: a systematic review and meta-analysis by Qi-Lun Lai, Meng-Ting Cai, Er-Chuang Li, Gao-Li Fang, Chun-Hong Shen, Yong-Feng Xu, Song Qiao, Jia-Jia Wang, Qin-Jie Weng, Yin-Xi Zhang

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A new effLuc/Kate dual reporter allele for tumor imaging in mice by Latifa Bakiri, Mélanie Tichet, Carolina Marques, Martin K. Thomsen, Elizabeth A. Allen, Stefanie Stolzlechner, Ke Cheng, Kazuhiko Matsuoka, Massimo Squatrito, Douglas Hanahan, Erwin F. Wagner

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The Impact of Drug Abuse on The Learner's Academic Performance in Kisoro Municipality Kisoro District. by Arinitwe, Edward

“…The study recommended that students should reduce and if possible abstain from drugs taking if they are to keep track of education well and improve their academic performance, the government should intervene by putting strict laws on the way sellers of drugs should put the time to open their bars and to close them to reduce on drugs taking among people, students should look for other ways of reducing stress not to end it by drugs taking since it affects their brain and also affects their academic performance, students' leisure time should be spent productively on doing some activities like reading and discussing but not to spend it on drugs abusing if they are to move forward effectively with the education process and there should be massive sensitization on the dangers of drugs on academic performance of students to reduce and if possible end drugs taking among school learning children.…”
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Key of SDN/NFV development:development and challenge of orchestrator by Peng ZHAO, Xiaodong DUAN

“…Network function virtualization (NFV) and software defined networking (SDN) have been widely recognized as the main direction of the development of the next generation telecom network,and as the brain of the future network,orchestrator is the key for the operators to manage the network flexibly and maximize the advantages of new technologies.Firstly,the core position of orchestrator in the next generation network was described,and the technical architecture of orchestrator was introduced.Then,the development of orchestrator in the perspective of standardization and open source were introduced and analyzed.Finally,the relationship between standardization and open source was elaborated,including the integration of orchestrator and OSS,the support of orchestrator for SDN and the idea to realize the intelligent and automatic network operation relying on orchestrator.…”
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LTP after Stress: Up or Down? by Marian Joëls, Harm J. Krugers

“…When an organism is exposed to a stressful situation, corticosteroid levels in the brain rise. This rise has consequences for behavioral performance, including memory formation. …”
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Inflammatory Pseudotumor of the Head Presenting with Hemiparesis and Aphasia by K. Saifudheen, James Jose, V. Abdul Gafoor

“…Inflammatory pseudotumor most commonly occurs in the orbit and produces orbital pseudotumor, but extension into brain parenchyma is uncommon. We report a case of inflammatory pseudotumor involving sphenoid sinus, cavernous sinus, superior orbital fissure, orbital muscle, and intracranial extension into left temporal lobe producing right hemiparesis and wernicke's aphasia. …”
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DESCARTES’ ONTOLOGY AND THE IDEA OF NATURE CONTROL by Česlovas Kalenda

“… The idea of nature control in Western civilisation is not only connected with ecological-climatic conditions as well as with social conditions but also with the nature of people and the properties of thinking, which are only typical to the human brain’s functional asymmetry. It was decisive in the West, differently from the East, that a rational, analytic rudiment was developed which legalized the antipode between subject and object, nature and spirit. …”
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14-3-3 Proteins in Glutamatergic Synapses by Jiajing Zhang, Yi Zhou

“…The 14-3-3 proteins are a family of proteins that are highly expressed in the brain and particularly enriched at synapses. Evidence accumulated in the last two decades has implicated 14-3-3 proteins as an important regulator of synaptic transmission and plasticity. …”
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Facts About Iron by Linda B. Bobroff, Jennifer Hillan

“…Iron also is needed to keep the immune system healthy and help brain cells work normally. This 2-page fact sheet is a minor revision written by Linda B. …”
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Oxygen Therapy by Bonnie Solmes

“…A low oxygen level in arterial blood is also harmful to the heart, the brain and the pulmonary blood vessels. Oxygen therapy is used to break this cycle. …”
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