The Protective Role of Ambient Ultraviolet Radiation Against Dementia: An Ecological Analysis of Global Data by Wenpeng You

“…UVR, through both vitamin D‐dependent and independent mechanisms, influences physiological processes essential for brain health, such as reducing neuroinflammation, improving sleep regulation, and enhancing neuroplasticity. …”
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IL-6 is Upregulated in Late-Stage Disease in Monkeys Experimentally Infected with Trypanosoma brucei rhodesiense by Dawn Nyawira Maranga, John Maina Kagira, Christopher Kariuki Kinyanjui, Simon Muturi Karanja, Naomi Wangari Maina, Maina Ngotho

“…The late stage was characterized by significant (P<0.05) elevation of CSF IL-6, white blood cell count, and total protein starting 35 dpi with peak levels of these parameters coinciding with relapse parasitaemia. Brain immunohistochemical staining revealed an increase in brain glial fibrillary acidic protein expression indicative of reactive astrogliosis in infected animals which were euthanized in late-stage disease. …”
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Qualitative systematic review on the lived experience of functional neurological disorder by Loyola McLean, Andrea Szasz, Anthony Korner

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The visuomotor synchronization immersive virtual reality of a depression avatar in a stigma context experience mobilizes the fronto-parietal cortex and anterior insula by Kelssy Hitomi dos Santos Kawata, Kelssy Hitomi dos Santos Kawata, Wey Guan Lem, Koki Ono, Hiroshi Oyama

“…Although neuroimaging studies have explored the neural correlates of some SoE subcomponents of visuomotor synchronization, the neural correlates of individual differences in SoE and how humans acquire virtual body representations through SoE subcomponents remain to be investigated.MethodsHere, we used the right hand of a virtual patient with depression in immersive virtual reality (IVR) to induce SoE in participants and measured whole brain activity using functional magnetic resonance imaging (fMRI). …”
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Gliosarcoma with Primary Skull Base Invasion by Quoc-Bao D. Nguyen, Avital Perry, Christopher S. Graffeo, Cody L. Nesvick, Aditya Raghunathan, Mark E. Jentoft, Brian P. O’Neill, Padraig P. Morris, Jonathan M. Morris, Jamie J. Van Gompel

“…Head CT demonstrated a 6 cm mass with marked bony erosion. Brain MRI at a one-week interval more clearly characterized tumor extension through the right orbit and muscles of mastication, with overall growth to 7 cm and worsening midline shift. …”
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Exploration and Verification of Prognostic Value of Endothelial Cells in Glioblastoma by Hengchao MA, Yuyang LIU, Jun XU, Bingyan TAO, Jun ZHANG

“…The expression of the target gene in GBM tissues and normal brain tissues around the tumor was significantly up-regulated detected by qPCR. …”
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Unravelling the Enigma of Highly Superior Autobiographical Memory: Signs, Symptoms and Treatment Perspectives: A Narrative Review by Rohit Wani, Bhagyesh Sapkale, Supriya Meshram, Sachin R Gedam

“…While the mechanism by which certain treatments become effective for HSAM is poorly understood, the use of interventions such as deep brain stimulation or cognitive-behavioural therapy may be warranted. …”
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Starvation-induced metabolic rewiring affects mTORC1 composition in vivo by Edgar Kaade, Simone Mausbach, Nina Erps, Marc Sylvester, Farhad Shakeri, Ron D. Jachimowicz, Volkmar Gieselmann, Melanie Thelen

“…In brain, mTORC1 activity remained unchanged during starvation. …”
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Molecular Imaging of Gliomas by A. H. Jacobs, C. Dittmar, A. Winkeler, G. Garlip, W. D. Heiss

“…Gliomas are the most common types of brain tumors. Although sophisticated regimens of conventional therapies are being carried out to treat patients with gliomas, the disease invariably leads to death over months or years. …”
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A 3D semantic segmentation network for accurate neuronal soma segmentation by Li Ma, Qi Zhong, Yezi Wang, Xiaoquan Yang, Qian Du

“…The proposed MSAW-based semantic segmentation network (MSAW-Net) was evaluated on three neuronal soma images from mouse brain and one neuronal soma image from macaque brain, demonstrating the efficiency of the proposed method. …”
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Comparison Of Glucagon Like Peptide/1 Levels In Diabetic Women With Ovarian Polycystic Syndrome And Healthy Women by Namra Iqtidar, Imran Ali Zaidi, Sobia Niaz, Javaria Latif, Amir Naveed, Ayesha Yousaf

“…Mostly it is found in islet pancreatic beta-cells, in the brain, in the cardiovascular system, and the lungs. …”
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Quercetin attenuates cisplatin-induced fatigue through mechanisms associated with the regulation of the HPA axis and MCP-1 signaling by Cheng-Hung Chuang, Yu-An Tai, Ting-Jing Wu, Ying-Jui Ho, Shu-Lan Yeh, Shu-Lan Yeh

“…The main objective of the present study was to investigate whether quercetin regulates the hypothalamic-pituitary-adrenal (HPA) axis and chemoattractant protein-1 (MCP-1) signaling, two factors contributing to CRF in mice exposed to cisplatin.MethodsMale BALB/c mice were randomly assigned to the following five groups for 15 weeks: Control, CDDP, CDDP+TAK779 (an antagonist of MCP-1 receptor, human CC chemokine receptor R2 (CCR2)), CDDP+OQ (a diet containing 1% quercetin) and CDDP+IQ (quercetin given by ip, 10 mg/kg, 3 times/week).ResultsThe results first showed that OQ and IQ significantly increased grip strength and locomotor activity, decreased plasma cortisol/corticosterone levels, and decreased the corticotropin releasing hormone (CRH) mRNA level in the brain tissues in mice exposed to CDDP. OQ and IQ also decreased CDDP-induced plasma levels of MCP-1 as well as the mRNA expression of MCP-1 and CCR2 in the brain stem. …”
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The Role of Glucocorticoid Receptors in Dexamethasone-Induced Apoptosis of Neuroprogenitor Cells in the Hippocampus of Rat Pups by Chun-I Sze, Yung-Chieh Lin, Yuh-Jyh Lin, Ting-Hui Hsieh, Yu Min Kuo, Chyi-Her Lin

“…However, Dex treatment results in adverse effects on the brain. Since the hippocampus contains a high density of glucocorticoid receptors (GCRs), we hypothesized that Dex affects neurogenesis in the hippocampus through inflammatory mediators. …”
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T-2 toxin triggers depression-like behaviors via upregulation of dopamine transporter in nucleus accumbens of male mice by Zhigang Chen, Shaoyi Duan, Jialu Li, Jianming Su, Hongyu Lei

“…Existing evidence suggests that the ingested T-2 toxin can enter the brain and exhibit neurotoxicity. However, it is still unknown whether T-2 toxin causes the depression-like behaviors. …”
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Seven Capital Devices for the Future of Stroke Rehabilitation by M. Iosa, G. Morone, A. Fusco, M. Bragoni, P. Coiro, M. Multari, V. Venturiero, D. De Angelis, L. Pratesi, S. Paolucci

“…In this paper, we have taken into account seven promising technologies that can improve rehabilitation of patients with stroke in the early future: (1) robotic devices for lower and upper limb recovery, (2) brain computer interfaces, (3) noninvasive brain stimulators, (4) neuroprostheses, (5) wearable devices for quantitative human movement analysis, (6) virtual reality, and (7) tablet-pc used for neurorehabilitation.…”
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Impact of post-traumatic stress disorder on epileptogenic networks: a functional connectivity study by Lisa-Dounia Soncin, Sara Simula, Nicolas Hemmer, Hélène Mourre, Marie Arthuis, Julia Makhalova, Christian Benar, Sylvane Faure, Fabrice Bartolomei

“…Results revealed increased FC in PTSD + subjects in the brain regions involved in PTSD, but only in the hemisphere ipsilateral to the epileptogenic zone. …”
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A Quantum-Based Machine Learning Approach for Autism Detection Using Common Spatial Patterns of EEG Signals by S. Saranya, R. Menaka

“…Electroencephalography (EEG) has emerged as a non-invasive tool to capture brain activity and facilitate the early detection of ASD using machine learning techniques. …”
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Differential gene expression during recall of behaviorally conditioned immune enhancement in rats: a pilot study [version 3; peer review: 1 approved, 3 approved with reservations] by Marcus Picard-Mareau, Markus Rueckels

“…Conclusions Our data indicate that in addition to the classic HPA axis, there could be additional pathways as e.g. the cholinergic anti-inflammatory pathway (CAIP), connecting brain and immune system, modulating and finetuning communication between brain and immune system.…”
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The role of potential oxidative biomarkers in the prognosis of intracerebral hemorrhage and the exploration antioxidants as possible preventive and treatment options by Jiayong Yao, Xiaohong Dai, Xueping Yv, Lei Zheng, Jia Zheng, Binglin Kuang, Wei Teng, Weiwei Yu, Mingyue Li, Hongtao Cao, Wei Zou, Wei Zou

“…Intracerebral hemorrhage (ICH) is a non traumatic hemorrhage that occurs in a certain part of the brain. It usually leads to brain cell damage. According to a large number of experimental research, oxidative stress is an important pathophysiological processes of cerebral hemorrhage. …”
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Extracellular Cardiolipin Modulates Select Immune Functions of Astrocytes in Toll-Like Receptor (TLR) 4-Dependent Manner by Taryn E. Murray, Tyler J. Wenzel, Svetlana Simtchouk, Bridget K. Greuel, Julien Gibon, Andis Klegeris

“…In addition to their homeostatic functions, astrocytes participate in neuroimmune responses of the brain and express TLR 4. Therefore, we hypothesized that extracellular CL (1) modulates the secretion of cytokines and cytotoxins by astrocytes, as well as their phagocytic activity, and (2) acts by interacting with astrocyte TLR 4. …”
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