Temporal dynamics of neonatal hypoxic–ischemic encephalopathy injuries on magnetic resonance imaging by Holly Flyger, Samantha J. Holdsworth, Alistair J. Gunn, Laura Bennet, Hamid Abbasi

“…Conversely, although most reports examined the prognostic value of scans taken between 4 and 10 days after birth, there is evidence from small numbers of cases that, at times, brain injury may continue to evolve for weeks after birth. …”
Get full text

Right Amygdalar and Temporofrontal Activation During Autobiographic, But Not During Fictitious Memory Retrieval by Hans J. Markowitsch, Alexander Thiel, Mechthild Reinkemeier, Josef Kessler, Adem Koyuncu, Wolf-Dieter Heiss

“…The principally activated brain regions overlapped considerably and constituted temporal and inferior prefrontal regions plus the cerebellum. …”
Get full text

SEEG-Based Bilateral Seizure Network Analysis for Neurostimulation Treatment by Genchang Peng, Mehrdad Nourani, Jay Harvey

“…Stereo-electroencephalography (SEEG) is a minimally invasive technique to monitor and evaluate brain activities during seizures before stimulator implantation. …”
Get full text

IGF-1 Restores Visual Cortex Plasticity in Adult Life by Reducing Local GABA Levels by José Fernando Maya-Vetencourt, Laura Baroncelli, Alessandro Viegi, Ettore Tiraboschi, Eero Castren, Antonino Cattaneo, Lamberto Maffei

“…Insulin-like growth factor 1 (IGF-1) is a peptide implicated in prenatal and postnatal phases of brain development such as neurogenesis, neuronal differentiation, synaptogenesis, and experience-dependent plasticity. …”
Get full text

Antioxidative Activity of Ferrocenes Bearing 2,6-Di-Tert-Butylphenol Moieties by E. R. Milaeva, S. I. Filimonova, N. N. Meleshonkova, L. G. Dubova, E. F. Shevtsova, S. O. Bachurin, N. S. Zefirov

“…The antioxidative activity of ferrocenes bearing either 2,6-di-tert-butylphenol or phenyl groups has been compared using DPPH (1,1-diphenyl-2-picrylhydrazyl) test and in the study of the in vitro impact on lipid peroxidation in rat brain homogenate and on some characteristics of rat liver mitochondria. …”
Get full text

Targeting Soluble Amyloid Oligomers in Alzheimer’s Disease: A Hypothetical Model Study Comparing Intrathecal Pseudodelivery of mAbs Against Intravenous Administration by Manuel Menendez-Gonzalez

“…Traditional intravenous (IV) monoclonal antibodies (mAbs) face challenges, including limited brain penetration and risks such as amyloid-related imaging abnormalities (ARIA). …”
Get full text

Recent Advances in the Pathogenesis of Syndromic Autisms by A. Benvenuto, B. Manzi, R. Alessandrelli, C. Galasso, P. Curatolo

“…Metabolic and mitochondrial defects may have toxic effects on the brain cells, causing neuronal loss and altered modulation of neurotransmission systems. …”
Get full text

Therapeutic Approaches to Tackle the Challenge of Depression That Is Resistant to Treatment–A Narrative Review by Md. Rajdoula Rafe, Abdul Waris, Pranoy Saha

“…Nonpharmacological interventions, including brain stimulation such as theta burst stimulation, deep brain stimulation, electroconvulsive therapy, repetitive transcranial magnetic stimulation, intermittent transcranial magnetic stimulation, and magnetic seizure therapy, as well as psychotherapeutic approaches, are being explored for the management of TRD in both present and future contexts. …”
Get full text

Developmental Changes in Sleep Spindle Characteristics and Sigma Power across Early Childhood by Ian J. McClain, Caroline Lustenberger, Peter Achermann, Jonathan M. Lassonde, Salome Kurth, Monique K. LeBourgeois

“…Our data characterize early developmental changes in sleep spindles, which may advance understanding of thalamocortical brain connectivity and associated lifelong disease processes. …”
Get full text

Cerebral compliance assessment from intracranial pressure waveform analysis: Is a positional shift-related increase in intracranial pressure predictable? by Donatien Legé, Pierre-Henri Murgat, Russell Chabanne, Kevin Lagarde, Clément Magand, Jean-François Payen, Marion Prud'homme, Yoann Launey, Laurent Gergelé

“…Real-time monitoring of intracranial pressure (ICP) is a routine part of neurocritical care in the management of brain injury. While mainly used to detect episodes of intracranial hypertension, the ICP signal is also indicative of the volume-pressure relationship within the cerebrospinal system, often referred to as intracranial compliance (ICC). …”
Get full text

Manganese Neurotoxicity as a Complication of Chronic Total Parenteral Nutrition by Alisha Khan, Jonathan Hingre, Amit S. Dhamoon

“…We provided care for a 38-year-old female on chronic TPN who presented to the hospital with Parkinsonian features, confusion, falls, and lethargy. MRI brain showed T1 hyperintensities in the bilateral globus pallidi, which were attributed to manganese toxicity from chronic TPN use. …”
Get full text

Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice by Eunjin Sohn, Bu-Yeo Kim, Yu Jin Kim, Joo-Hwan Kim, Soo-Jin Jeong

“…EEBC also reversed the SCO-induced changes in apoptosis-related protein expression in brain tissues. Furthermore, EEBC significantly reduced malondialdehyde levels and activated catalase in SCO-administered brains. …”
Get full text

Passive Monitoring of Parkinson Tremor in Daily Life: A Prototypical Network Approach by Luc J. W. Evers, Yordan P. Raykov, Tom M. Heskes, Jesse H. Krijthe, Bastiaan R. Bloem, Max A. Little

Get full text

It’s Hard to Prepare for Task Novelty: Cueing the Novelty of Upcoming Tasks Does Not Facilitate Task Performance by Mengqiao Chai, Ana F. Palenciano, Ravi Mill, Michael W. Cole, Senne Braem

“…Previous studies suggest that our brain relies on different networks for rapid task learning versus retrieving known tasks from memory, and behavioral studies have shown that novel versus practiced tasks may rely on different task configuration processes. …”
Get full text

A hybrid critical channels and optimal feature subset selection framework for EEG fatigue recognition by Hanying Guo, Siying Chen, Yongjiang Zhou, Ting Xu, Yuhao Zhang, Hongliang Ding

“…These electrode channels are used to construct a Functional Brain Network (FBN), from which the topological feature set is extracted. …”
Get full text

Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice by Jiyeon Hwang, Sangbhin Lee, Junichi Okada, Li Liu, Jeffrey E. Pessin, Streamson C. Chua, Gary J. Schwartz, Young-Hwan Jo

“…Abstract The visceral organ-brain axis, mediated by vagal sensory neurons, is essential for maintaining various physiological functions. …”
Get full text

Rational engineering of minimally immunogenic nucleases for gene therapy by Rumya Raghavan, Mirco J. Friedrich, Indigo King, Samuel Chau-Duy-Tam Vo, Daniel Strebinger, Blake Lash, Michael Kilian, Michael Platten, Rhiannon K. Macrae, Yifan Song, Lucas Nivon, Feng Zhang

Get full text

Targeted lipidomics analysis of possible molecular mechanisms of lipid changes in temporal lobe epilepsy models by Huaiyu Sun, Xuewei Li, Zhiqing Chen, Hongmei Meng

“…Seizures can cause changes in lipid metabolism in the brain. In-depth studies at multiple levels are urgently needed to elucidate lipid composition, distribution, and metabolic pathways in the brain after seizure.MethodsIn this research, a cutting-edge targeted quantitative lipidomics study was conducted on the hippocampal tissues of six rats with temporal lobe epilepsy and six normal rats. …”
Get full text

Enhanced Temporal Coupling between Thalamus and Dorsolateral Prefrontal Cortex Mediates Chronic Low Back Pain and Depression by Hong Li, Qiaoyan Song, Ruya Zhang, Youlong Zhou, Yazhuo Kong

“…Numerous neuroimaging studies have demonstrated that the brain plasticity is associated with chronic low back pain (cLBP). …”
Get full text

Sex differences in aggression and its neural substrate in a cichlid fish by Lillian R. Jackson, Mariam Dumitrascu, Beau A. Alward

“…We then quantified neural activation patterns in brain regions of the social behavior network (SBN) to investigate if differences in behavior are reflected in the brain with immunohistochemistry by detecting the phosphorylated ribosome marker phospho-S6 ribosomal protein (pS6), a marker for neural activation. …”
Get full text