MRI Correlates of Parkinson’s Disease Progression: A Voxel Based Morphometry Study by Valentina Fioravanti, Francesca Benuzzi, Luca Codeluppi, Sara Contardi, Francesco Cavallieri, Paolo Nichelli, Franco Valzania

“…PD is associated with brain morphological changes in cortical and subcortical structures. …”
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The Krushinsky – Molodkina genetic rat strain as a unique experimental model of seizure states by I. I. Poletaeva, Z. A. Kostyna, N. M. Surina, I. B. Fedotova, Z. A. Zorina

“…The study of genetic mechanisms, which underlie normal and abnormal behavioral traits, are important not only for fundamental knowledge of CNS function, but also for human well-being, as well as in the aspect of treatment of brain diseases. Accumulation of knowledge concerning the functions of genes, which are expressed in the CNS and are involved in the specific brain functions determined now by the success of molecular genetics, but it could not overshadow the importance of phenotype expression investigation of genetically determined traits, especially pathological ones. …”
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Aesthetic evaluation underpinning brand love relationship development: an activation likelihood estimation meta-analysis and multivariate analysis by Shinya Watanuki

“…We adopted three major meta-analytic decoding analysis modules to objectively interpret these brain regions, namely, Neurosynth, NeuroQuery, and the Behavioral Analysis plugin (BrainMap platform). …”
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Metabolic Differences in Neuroimaging with [¹⁸F]FDG in Rats Under Isoflurane and Hypnorm–Dormicum by Aage Kristian Olsen Alstrup, Mette Simonsen, Kim Vang Hansen, Caroline C. Real

“…The rats were submitted to dynamic [¹⁸F]FDG PET scan. The whole brain [¹⁸F]FDG standard uptake value (SUV) and the brain voxel-based analysis were performed. …”
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Dendritic growth and synaptic organization from activity-independent cues and local activity-dependent plasticity by Jan H Kirchner, Lucas Euler, Ingo Fritz, André Ferreira Castro, Julijana Gjorgjieva

“…How they emerge simultaneously during brain development as neurons become integrated into functional networks is still not mechanistically understood. …”
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Abnormal alterations in structure-function coupling at the modular level in patients with postherpetic neuralgia by Zihan Li, Jian Jiang, Xiaofeng Jiang, Yangyang Xie, Jing Lu, Lili Gu, Shunda Hong

“…Based on AAL(90) mapping, the brain network was divided into 9 modules, and the structural–functional connectivity (SC–FC) coupling was compared at the whole-brain level and within the modules, as well as alterations in the topological properties of the brain network in the patient group. …”
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Understanding the Impact of Urinary Incontinence in Persons with Dementia: Development of an Interdisciplinary Service Model by Patrick Juliebø-Jones, Elizabeth Coulthard, Elizabeth Mallam, Hilary Archer, Marcus J. Drake

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A Systematic Review on Serious Games in Attention Rehabilitation and Their Effects by Leila Shahmoradi, Fatemeh Mohammadian, Meysam Rahmani Katigari

“…Attention is a basic and main mental task and can play an important role in the functioning of other brain abilities such as intelligence, memory, learning, and perception, and its deficit occurs in 80% of patients with traumatic brain injury. …”
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Renin-angiotensin-aldosterone system in ISIAH rats with stressinduced arterial hypertension by A. D. Dubinina, E. V. Antonov, L. A. Fedoseeva, E. N. Pivovarova, A. L. Markel, L. N. Ivanova

“…By contrast, a significant increase of RAS genes expression was found in the brain tissues. The mRNA of the Ren gene was increased in the hypothalamus, and the mRNA of Ace gene was increased in the brain stem of the ISIAH rats. …”
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Efficient Hardware Implementation of a Multi-Layer Gradient-Free Online-Trainable Spiking Neural Network on FPGA by Ali Mehrabi, Yeshwanth Bethi, Andre van Schaik, Andrew Wabnitz, Saeed Afshar

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Correlations of inflammatory processes caused by cerebral stroke with the outcome of the disease by A. Vaitkus, J. Valinčiūtė, S. Gylytė

“…Positive influence of inflammatory cells and mediators in brain injury patients. All inflammatory cells and mediators play a positive role in complicating the pathological response to stroke and also in maintaining brain cell homeostasis. …”
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Nanotherapeutic smart approaches for combating Alzheimer’s disease and overcoming existing obstacles: A novel eco-friendly green approach by Ahmed M. Almehdi, Doha H. Aboubaker, Rania Hamdy, Ali El-Keblawy

“…Even after the disease has started, brain tissue integrity may degenerate. The physiological characteristics of the highly selective blood-brain barrier and the electrostatic charge of the nanoporous extracellular matrix have long placed restrictions on the treatment of brain disorders. …”
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Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS) by Delfina Larrea, Kirstin A. Tamucci, Khushbu Kabra, Kevin R. Velasco, Taekyung D. Yun, Marta Pera, Jorge Montesinos, Rishi R. Agrawal, Carmen Paradas, John W. Smerdon, Emily R. Lowry, Anna Stepanova, Belem Yoval-Sanchez, Alexander Galkin, Hynek Wichterle, Estela Area-Gomez

“…Over time, this deficiency alters mitochondrial electron flow and the active/dormant status of complex I in spinal cord tissues, but not in the brain. These findings suggest mitochondria-associated ER membranes (MAM domains) play a crucial role in regulating cellular glucose metabolism and that MAM dysfunction may underlie the bioenergetic deficits observed in ALS.…”
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Body position influence on cerebrospinal fluid volume redistribution inside the cranial and spinal CSF compartments by I. Strbačko, M. Radoš, I. Jurjević, D. Orešković, M. Klarica, M. Klarica

“…IntroductionIt is generally accepted that during body position changes from horizontal to vertical there is a short-lasting shift of a certain CSF volume from the cranium into the hydrostatically lower parts of the spinal space, which leads to transitory CSF pressure decrease to negative values.MethodsIn order to test this, we performed MRI volumetry of cranial and spinal part of the CSF space in healthy volunteers of both genders (n = 22) in three different body positions [horizontal (H); elevated head and upper body (H-UP) under an angle about 30° from the base; elevated lower body (B-UP) under an angle about 30° from the base].ResultsVolumes of brain and spinal cord tissue did not change during body position changes. …”
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Effect of Electroacupuncture at Shenting and Baihui Acupoints on Ability of Learning and Memory and Expression of Autophagy Related Genes and Proteins in Cerebral Ischemia-reperfus... by Lingli GAO, Xiaodong FENG

“…Morris water maze experiment was used to observe learning and memory ability of rats, TTC staining was used to observe the change of brain infarction area of rats, RT-PCR and Western Blot were used to detect the expression of autophagy related genes and proteins in hippocampus.Results:④Morris water maze outcomes showed that compared with the model group, the escape latency time of rats in the EA group was obviously shortened, the number of across-platform was increased and the distance was shortened (<italic>P</italic>&lt;0.05).④Compared with the model group, the nerve defect scale of brain ischemia-reperfusion injury rats in the EA group was decreased (<italic>P</italic>&lt;0.05).④TTC staining results showed that the area of brain infarction in the EA group and model group was respectively higher than that in the sham operation group, and the volume of brain infarction in the EA group was reduced compared with the model group (<italic>P</italic>&lt;0.05).④Compared with the model group, the levels of Beclin 1, LC3Ⅰ/Ⅱand PI3K mRNA and protein in the left side of hippocampus in the EA group were increased (<italic>P</italic>&lt;0.05).Conclusion:EA at the DU24 and DU20 acupoints can reduce the cerebral infarction, and improve animal behaviors, and protect the neuronal injury. …”
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DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis by M. Dierssen, M. Martínez de Lagrán

“…This review focuses on the functional role that DYRK1A plays in brain development.…”
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Bilateral Medial Medullary Stroke: A Challenge in Early Diagnosis by Amir M. Torabi

“…MR of C-spine showed lesion at medial medulla; therefore a second MRI of brain was requested, showed characteristic “heart appearance” shape at diffusion weighted (DWI), and confirmed bilateral medial medullary stroke. …”
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Regulation of Glial Cell Functions by PPAR-𝜸 Natural and Synthetic Agonists by Antonietta Bernardo, Luisa Minghetti

“…In the present article, we will review the recent findings supporting a major role for PPAR-𝛾 agonists in controlling neuroinflammation and neurodegeneration through their activities on glial cells, with a particular emphasis on microglial cells as major macrophage population of the brain parenchyma and main actors in brain inflammation.…”
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Insulin in Central Nervous System: More than Just a Peripheral Hormone by Ana I. Duarte, Paula I. Moreira, Catarina R. Oliveira

“…Insulin signaling in central nervous system (CNS) has emerged as a novel field of research since decreased brain insulin levels and/or signaling were associated to impaired learning, memory, and age-related neurodegenerative diseases. …”
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The Impact of Antidepressants on Gut Microbiome and Depression Management by Ee-Kit Tang, Ke-Yan Loo, Angel Yun-Kuan Thye, Jodi Woan-Fei Law, Loh Teng-Hern Tan, Malarvili Selvaraja, Sivakumar Thurairajasingam, Learn-Han Lee, Vengadesh Letchumanan

“…Recent advances in psychiatric research have revealed a connection between the gut-brain axis, a bidirectional communication system linking the brain's emotional and cognitive centers with intestinal functions. …”
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