Restraint stress effects on glutamate signaling protein levels in the rats’ frontal cortex: Does β1 adrenoceptor activity matter? by Agnieszka Zelek-Molik, Anna Gądek-Michalska, Michał Wilczkowski, Adam Bielawski, Katarzyna Maziarz, Grzegorz Kreiner, Irena Nalepa

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Individualized gray matter morphological abnormalities unveil two neuroanatomical obsessive-compulsive disorder subtypes by Baohong Wen, Keke Fang, Qiuying Tao, Ya Tian, Lianjie Niu, Wenqing Shi, Zijun Liu, Jin Sun, Liang Liu, Xiaopan Zhang, Ruiping Zheng, Hui-Rong Guo, Yarui Wei, Yong Zhang, Jingliang Cheng, Shaoqiang Han

“…To gain deeper insights into the connectomic and molecular underpinnings of structural brain abnormalities in the identified subtypes, we investigated their associations with normal brain network architecture and the distribution of neurotransmitter receptors/transporters. …”
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Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota by Xiaoxia He, Xiaofeng Yuan, Qilin Shu, Yayang Gao, Youli Chen, Yao Liu, Yao Liu, Yao Liu, Jian Xu, Jian Xu, Jian Xu, Yongping Zhang, Yongping Zhang, Yongping Zhang, Guoqiong Cao, Guoqiong Cao, Guoqiong Cao

“…The different groups of animals were compared in terms of neurological score, cerebral infarct volume, brain edema, brain and gut histopathology to assess stroke severity. …”
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Variables associated with cognitive function: an exposome-wide and mendelian randomization analysis by Yong-Li Zhao, Yi-Ning Hao, Yi-Jun Ge, Yi Zhang, Lang-Yu Huang, Yan Fu, Dan-Dan Zhang, Ya-Nan Ou, Xi-Peng Cao, Jian-Feng Feng, Wei Cheng, Lan Tan, Jin-Tai Yu

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Comparing the emotional impact of the UK COVID-19 lockdown in very preterm and full-term born children: a longitudinal study by Zeyuan Sun, Zeyuan Sun, Laila Hadaya, Laila Hadaya, Marguerite Leoni, Marguerite Leoni, Paola Dazzan, Emily Simonoff, Serena J. Counsell, A. David Edwards, Chiara Nosarti, Chiara Nosarti, Lucy Vanes

“…This study aimed to understand the emotional impact of the COVID-19 lockdown on children who were born very preterm (VPT, <32 weeks' gestation), as they are vulnerable to mental health difficulties and are at increased risk of developing psychiatric problems during childhood compared to their full-term-born counterparts.MethodsThe parents of 32 VPT children (mean age = 8.7) and 29 term-born controls (mean age = 8.8), who had previously taken part in a study of brain development and psychopathology following VPT birth, completed an online modified version of the Coronavirus Health and Impact Survey (CRISIS). …”
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Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlle... by Jeremy Chataway, Suvankar Pal, Charis Wong, Elizabeth Elliott, Jenna M Gregory, Siddharthan Chandran, Judith Newton, Shuna Colville, Maria Stavrou, Christopher J Weir, Nigel Stallard, Malcolm R Macleod, Michelle Steven, Richard Anthony Parker, Arpan R Mehta, Robert J Swingler, Mahesh K B Parmar, Rachel S Dakin, Jill Williamson

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Positron Emission Tomographic Imaging of the Cannabinoid Type 1 Receptor System with [C]OMAR ([C]JHU75528): Improvements in Image Quantification Using Wild-Type and Knockout Mice by Raúl Herance, Santiago Rojas, Sergio Abad, Xavier Jiménez, Juan Domingo Gispert, Olga Millán, Elena Martín-García, Aurelijus Burokas, Miquel Àngel Serra, Rafael Maldonado, Deborah Pareto

“…Brain uptake in WT animals was higher (50%) than in KO animals in baseline conditions. …”
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Activity-Dependent NPAS4 Expression and the Regulation of Gene Programs Underlying Plasticity in the Central Nervous System by José Fernando Maya-Vetencourt

“…The capability of the brain to change functionally in response to sensory experience is most active during early stages of development but it decreases later in life when major alterations of neuronal network structures no longer take place in response to experience. …”
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Pathogenesis of Hepatic Encephalopathy by Irena Ciećko-Michalska, Małgorzata Szczepanek, Agnieszka Słowik, Tomasz Mach

“…Hyperammonemia plays the most important role in the pathogenesis of hepatic encephalopathy. The brain-blood barrier disturbances, changes in neurotransmission, neuroinflammation, oxidative stress, GABA-ergic or benzodiazepine pathway abnormalities, manganese neurotoxicity, brain energetic disturbances, and brain blood flow abnormalities are considered to be involved in the development of hepatic encephalopathy. …”
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Scale-free behavior of weight distributions of connectomes by Michelle Cirunay, Géza Ódor, István Papp, Gustavo Deco

“…To determine the precise link between anatomical structure and function, brain studies primarily concentrate on the anatomical wiring of the brain and its topological properties. …”
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Newborn screening and the screening laboratory: past, present and future by Anita Boelen, Annemieke C Heijboer

“…Thyroid hormone (TH) is essential for brain development in utero and during the first 2 to 3 years of life. …”
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Systemic and Local CC Chemokines Production in a Murine Model of <emph>Listeria monocytogenes</emph> Infection

“…This is in correlation with slight inflammatory infiltrates found in the brain tissue early in infection.</p>…”
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Modeling the Encephalopathy of Prematurity in Animals: The Important Role of Translational Research by Hannah C. Kinney, Joseph J. Volpe

“…Translational research in preterm brain injury depends upon the delineation of the human neuropathology in order that animal models faithfully reiterate it, thereby ensuring direct relevance to the human condition. …”
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A Case of Calcified Metastatic Colorectal Adenocarcinoma Mimicking a Benign Lesion: Pitfalls in Diagnosis by Peter Michail, Iftah Amith, Sanila George, Mathew K. George

“…Therefore the presence of a calcified brain lesion in a patient with a positive oncological history requires a high index of suspicion for brain metastases. …”
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Probing Neural Transplant Networks In Vivo with Optogenetics and Optogenetic fMRI by Andrew J. Weitz, Jin Hyung Lee

“…Understanding how stem cell-derived neurons functionally integrate into the brain upon transplantation has been a long sought-after goal of regenerative medicine. …”
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Perinatal Cerebellar Injury in Human and Animal Models by Valerie Biran, Catherine Verney, Donna M. Ferriero

“…Cerebellar injury is increasingly recognized through advanced neonatal brain imaging as a complication of premature birth. …”
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Clinical Application of Transcranial Magnetic Stimulation for Stroke Rehabilitation by Yi WU

“…As a non-invasive brain stimulation technique, transcranial magnetic stimulation(TMS)can change the membrane potential of neurocytes and generate induced current through time-varying pulse magnetic field acting on central nervous system, which can also affect metabolism and neuroelectric activity in the brain and lead to a series of physiological and biochemical reactions. …”
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Nonhematopoietic Variants of Erythropoietin in Ischemic Stroke: Need for Step-Wise Proof-of-Concept Studies by Dirk M. Hermann

“…In view of the potential clinical use of Neuro-EPO, stringent proof-of-concept studies are urgently needed to define (1) how intranasally delivered Neuro-EPO reaches the brain, (2) which concentrations are achieved in the ischemic and nonischemic brain tissue of rodents and nonhuman primates, and (3) which are the mechanisms via which Neuro-EPO protects from injury. …”
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Repetitive Transcranial Magnetic Stimulation, Cognition, and Multiple Sclerosis: An Overview by Grigorios Nasios, Lambros Messinis, Efthimios Dardiotis, Panagiotis Papathanasopoulos

“…A major aspect of the disease is brain volume loss (BVL), present in all phases and types (relapsing and progressive) of the disease and linked to both motor and cognitive disabilities. …”
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Rapid Spontaneous Regression of Traumatic Subdural Hematoma by Prashant Punia, Ashish Chugh, Sarang Gotecha, Neeraj Singh, Jayant Gaud, Ishant Rege, Ramis Abdul Aziz

“…Large SDH collects along the convexity of the brain causing compression over the brain stem with midline shift. …”
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