An unconstrained four pool model analysis of proton relaxation and magnetization transfer in ex vivo white matter by Niklas Wallstein, André Pampel, Roland Müller, Carsten Jäger, Markus Morawski, Harald E. Möller

“…Abstract Understanding proton relaxation in the brain’s white matter remains an active field of magnetic resonance imaging research. …”
Get full text

Control of Cellular Differentiation Trajectories for Cancer Reversion by Jeong‐Ryeol Gong, Chun‐Kyung Lee, Hoon‐Min Kim, Juhee Kim, Jaeog Jeon, Sunmin Park, Kwang‐Hyun Cho

Get full text

Neuronal guidance factor Sema3A inhibits neurite ingrowth and prevents chondrocyte hypertrophy in the degeneration of knee cartilage in mice, monkeys and humans by Shishu Huang, Dashuang Gao, Zhenxia Li, Hongchen He, Xi Yu, Xuanhe You, Diwei Wu, Ze Du, Jiancheng Zeng, Xiaojun Shi, Qinshen Hu, Yong Nie, Zhong Zhang, Zeyu Luo, Duan Wang, Zhihe Zhao, Lingli Li, Guanglin Wang, Liping Wang, Zongke Zhou, Di Chen, Fan Yang

Get full text

Caliper-based precise positioning of the target (CALIPPOT) for transcranial magnetic stimulation without neuronavigation system by Jue Wang, Zijian Feng, Yunsong Hu, Rong Zeng, Juan Yue, Qiu Ge, Hongxiao Wang, Yufeng Zang

Get full text

From Evaluation to Prediction: Behavioral Effects and Biological Markers of Cognitive Control Intervention by Bin Xuan

“…The intervention effect of cognitive control has been evaluated by behavioral performance, transfer effect, brain structure and function, and brain networks. …”
Get full text

Suppression of epileptic seizures by transcranial activation of K+-selective channelrhodopsin by Xiaodong Duan, Chong Zhang, Yujie Wu, Jun Ju, Zhe Xu, Xuanyi Li, Yao Liu, Schugofa Ohdah, Oana M. Constantin, Yifan Pan, Zhonghua Lu, Cheng Wang, Xiaojing Chen, Christine E. Gee, Georg Nagel, Sheng-Tao Hou, Shiqiang Gao, Kun Song

“…There is a critical need for effective inhibitory optogenetic tools that are highly light-sensitive and capable of suppressing neuronal activity in deep brain tissue. In this study, we developed a highly sensitive moderately K+-selective channelrhodopsin (HcKCR1-hs) by molecular engineering of the recently discovered Hyphochytrium catenoides kalium (potassium) channelrhodopsin 1. …”
Get full text

NF-κB1 p50 stabilizes HIF-1α protein through suppression of ATG7-dependent autophagy by Junlan Zhu, Shirui Huang, Yang Li, Jiheng Xu, Ruifan Chen, Mengxin Guo, Xiaohui Qian, Tengda Li, Zhongxian Tian, Honglei Jin, Chuanshu Huang

Get full text

Bioinformatics Analysis of the Human Surfaceome Reveals New Targets for a Variety of Tumor Types by André L. Fonseca, Vandeclécio L. da Silva, Marbella M. da Fonsêca, Isabella T. J. Meira, Thayná E. da Silva, José E. Kroll, André M. Ribeiro-dos-Santos, Cléber R. Freitas, Raimundo Furtado, Jorge E. de Souza, Beatriz Stransky, Sandro J. de Souza

Get full text

Wearable Sensors Measure Ankle Joint Changes of Patients with Parkinson’s Disease before and after Acute Levodopa Challenge by Zhuang Wu, Xu Jiang, Min Zhong, Bo Shen, Jun Zhu, Yang Pan, Jingde Dong, Pingyi Xu, Wenbin Zhang, Li Zhang

Get full text

Microglia depletion reduces neurodegeneration and remodels extracellular matrix in a mouse Parkinson’s disease model triggered by α-synuclein overexpression by Zhen Zhang, Kun Niu, Taoying Huang, Jiali Guo, Gongbikai Xarbat, Xiaoli Gong, Yunke Gao, Feiyang Liu, Shan Cheng, Wenting Su, Fei Yang, Zhaoyuan Liu, Florent Ginhoux, Ting Zhang

Get full text

Criticality is Associated with Future Psychotherapy Response in Patients with Post-Traumatic Stress Disorder—A Pilot Study by Remko van Lutterveld, Myrthe Sterk, Cristian Spitoni, Mitzy Kennis, Sanne J. H. van Rooij, Elbert Geuze

“…Recently, there is increased interest in brain criticality, which assesses the phase transition between order and disorder in brain activity. …”
Get full text

Medicolegal Considerations with Intravenous Tissue Plasminogen Activator in Stroke: A Systematic Review by Archit Bhatt, Adnan Safdar, Dhara Chaudhari, Diane Clark, Amber Pollak, Arshad Majid, Mounzer Kassab

Get full text

A Novel Hypothesis for Migraine Disease Mechanism: The Creation of a New Attractor Responsible for Migraine Disease Symptoms by Elham Baradari, Farnaz Garehdaghi, Yashar Sarbaz

“…This attractor has a one-scroll mode representing a healthy brain and a double-scroll mode representing a migraine sufferer brain. …”
Get full text

Activation of TMEM16E scramblase induces ligand independent growth factor receptor signaling and macropinocytosis for membrane repair by Jung-Eun Kim, Woori Ko, Siwoo Jin, Jin-Nyeong Woo, Yuna Jung, Inah Bae, Han-Kyoung Choe, Daeha Seo, Bertil Hille, Byung-Chang Suh

Get full text

Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets by Claire Vinel, James Boot, Weiwei Jin, Nicola Pomella, Alexandra Hadaway, Charles Mein, Nicolae Radu Zabet, Silvia Marino

“…Abstract Background Glioblastoma is the most common and aggressive malignant brain tumour in the adult population and its prognosis is dismal. …”
Get full text

Esophageal Gastrointestinal Stromal Tumor with Rare Intracranial Metastasis by José Carvalho, Margarida Teixeira, Francisco Teixeira Silva, Alexandra Esteves, Carlos Ribeiro, Diana Guerra

“…They commonly metastasize to the liver and peritoneum, but brain metastases are extremely rare. Clinical Case. …”
Get full text

Drosophila ubiquitin-specific peptidase 14 stabilizes the PERIOD protein by regulating a ubiquitin ligase SLIMB by So Who Kang, Jung-Eun Park, Soonhyuck Ok, Minhui Um, Hyeonjeong Son, Seunghee Byun, Nayoung Park, Su Jin Lee, Thị Xuân Thùy Trần, Gyeongmin Kim, Jeonghun Yeom, Kyunggon Kim, Eun Young Kim, Min-Ji Kang

Get full text

Identification of Intracranial Germ Cell Tumors Based on Facial Photos: Exploratory Study on the Use of Deep Learning for Software Development by Yanong Li, Yixuan He, Yawei Liu, Bingchen Wang, Bo Li, Xiaoguang Qiu

“… BackgroundPrimary intracranial germ cell tumors (iGCTs) are highly malignant brain tumors that predominantly occur in children and adolescents, with an incidence rate ranking third among primary brain tumors in East Asia (8%-15%). …”
Get full text

A cryo-shocked M2 macrophages based treatment strategy promoting repair of spinal cord injury via immunomodulation and axonal regeneration effects by Ermei Lu, Kecheng Zhou, Jiansen Miao, Yanlin Zhu, Jiyao Tang, Siting Du, Yanzhen Feng, Linyuan Jiang, Tianyao Jiang, Ting Huang, Ping Li, Xinjun Miao, Qi Han, Jian Xiao

Get full text

The medial and lateral orbitofrontal cortex jointly represent the cognitive map of task space by Liwei Tan, Yidan Qiu, Lixin Qiu, Shuting Lin, Jinhui Li, Jiajun Liao, Yuting Zhang, Wei Zou, Ruiwang Huang

“…Collectively, these findings provide an account that can increase our understanding of how the brain constructs abstract cognitive maps in a task-relevant space.…”
Get full text