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Dynamic Changes in the Nigrostriatal Pathway in the MPTP Mouse Model of Parkinson’s Disease
Published 2017-01-01“…The characteristic brain pathology and motor and nonmotor symptoms of Parkinson’s disease (PD) are well established. …”
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Functional Connectivity Alterations in Children with Spastic and Dyskinetic Cerebral Palsy
Published 2018-01-01“…However, the common and distinct dysfunctional characteristics between SCP and DCP on the brain network level are less known. This study aims to detect the alteration of brain functional connectivity in children with SCP and DCP based on resting-state functional MRI (fMRI). …”
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Exploring the neural mechanisms underlying cooperation and competition behavior: Insights from stereo-electroencephalography hyperscanning
Published 2025-02-01“…Cross-frequency coupling suggests that these gamma synchronizations result from intra- and inter-brain interactions. Competition stems from intra-brain alpha-gamma coupling from IFG to insula and inter-brain IFG alpha synchronization, while cooperation is driven by intra-brain beta-gamma coupling from insula to IFG and inter-brain insula beta synchronization. …”
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OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma
Published 2025-02-01“…Previously, we demonstrated that the growth of the paediatric brain malignancy, sonic hedgehog subgroup medulloblastoma, is rooted in a dysregulated developmental hierarchy, the apex of which is defined by characteristically quiescent SOX2+ stem-like cells. …”
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First-in-Human PET Imaging of [18F]SDM-4MP3: A Cautionary Tale
Published 2023-01-01Get full text
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Mapping and modeling age-related changes in intrinsic neural timescales
Published 2025-02-01“…Abstract Intrinsic timescales of brain regions exhibit heterogeneity, escalating with hierarchical levels, and are crucial for the temporal integration of external stimuli. …”
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Reduced frontotemporal connectivity during a verbal fluency task in patients with anxiety, sleep, and major depressive disorders
Published 2025-01-01“…Furthermore, clarifying the mechanisms underlying variations in executive function impairments across multiple psychiatric disorders will enhance our comprehension of brain activity alternations among these disorders. …”
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Systematic dissection of pleiotropic loci and critical regulons in excitatory neurons and microglia relevant to neuropsychiatric and ocular diseases
Published 2025-01-01“…To investigate the biological connections between the eye and brain, we integrated bulk and single-cell multiomic profiles with GWAS summary statistics for eight neuropsychiatric and five ocular diseases. …”
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Astrocytic proteins involved in regulation of the extracellular environment are increased in the Alzheimer's disease middle temporal gyrus
Published 2025-01-01“…Alzheimer's disease (AD) has complex pathophysiology involving numerous cell types and brain processes. Astrocyte involvement in AD is gaining increased attention, however a complete characterisation of astrocytic changes in the AD human brain is warranted. …”
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Stem Cell Tracking Technologies for Neurological Regenerative Medicine Purposes
Published 2017-01-01Get full text
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Construction of a Multimodal Neuroimaging Data Fusion System and Evaluation of Mental Fatigue Using Nonlinear Analysis
Published 2021-01-01“…Based on the binary and the weighted brain function networks, the relationship between the human brain fatigue and the brain function network is evaluated by calculating the fractal dimension. …”
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Bulk and single-cell transcriptome revealed the metabolic heterogeneity in human glioma
Published 2025-01-01Get full text
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Altered Functional Connectivity after Epileptic Seizure Revealed by Scalp EEG
Published 2020-01-01“…Epileptic seizures are considered to be a brain network dysfunction, and chronic recurrent seizures can cause severe brain damage. …”
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