Proteomic Analysis Reveals Growth Inhibition of Coriolus versicolor by Methanol Extracts of Cinnamomum camphora Xylem by Quan Li, Xiangyang Li, Hui Lin

“…Downregulated expression of aspartate aminotransferase, ATP synthase alpha chain, DEAD/DEAH-box helicase, and phosphoglycerate kinase showed that the methanol extracts of C. camphora xylem disrupted functional aspects such as nitrogen and carbon metabolism, energy metabolism, hormone signal response, and glucose metabolism, eventually leading to C. versicolor inhibition.…”
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Machine learning helps reveal key factors affecting tire wear particulate matter emissions by Zhenyu Jia, Jiawei Yin, Tiange Fang, Zhiwen Jiang, Chongzhi Zhong, Zeping Cao, Lin Wu, Ning Wei, Zhengyu Men, Lei Yang, Qijun Zhang, Hongjun Mao

“…Model-related (similarity network graph) and model-unrelated (partial dependence plots and centered-individual conditional expectation plots) explainability methods were used to break the black box of ML. Model explainability results show that the feature parameters-emission response relationships for tire wear PM2.5 and PM2.5-10 are different. …”
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Multiresponse Optimization of Mechanical and Physical Adsorption Properties of Activated Natural Fibers Hybrid Composites by G. Velmurugan, V. Siva Shankar, L. Natrayan, S. Sekar, Pravin P. Patil, M. Senthil Kumar, Subash Thanappan

“…To achieve these objectives, the following process parameters were determined, and RSM carried out optimization with the Box-Behnken experimental setup at three different levels: compression molding temperature (°C), pressure (bar), and time (min). …”
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Design and Optimization of Power Harrow Soil Crushing Components for Coastal Saline–Alkali Land by Nan Xu, Zhenbo Xin, Jin Yuan, Zenghui Gao, Yu Tian, Chao Xia, Xuemei Liu, Dongwei Wang

“…Subsequently, through simulation tests integrating the Discrete Element Method (DEM) and the Box–Behnken Design (BBD), the optimal parameter combination is identified. …”
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High Glucose-Induced Oxidative Stress Mediates Apoptosis and Extracellular Matrix Metabolic Imbalances Possibly via p38 MAPK Activation in Rat Nucleus Pulposus Cells by Xiaofei Cheng, Bin Ni, Feng Zhang, Ying Hu, Jie Zhao

“…The expression of ECM metabolism-related genes, including type II collagen, aggrecan, SRY-related high-mobility-group box 9 (Sox-9), matrix metalloproteinase 3 (MMP-3), and tissue inhibitor of metalloproteinase 1 (TIMP-1), was analyzed by semiquantitative RT-PCR. …”
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Development and Validation of HPLC Method for the Simultaneous Determination of Five Food Additives and Caffeine in Soft Drinks by Bürge Aşçı, Şule Dinç Zor, Özlem Aksu Dönmez

“…Box-Behnken design was applied to optimize high performance liquid chromatography (HPLC) conditions for the simultaneous determination of potassium sorbate, sodium benzoate, carmoisine, allura red, ponceau 4R, and caffeine in commercial soft drinks. …”
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The Role of Dopamine in Impulsivity and Substance Abuse: A Narrative Review by Connor J Plaisance, Lloyd F Ledet III, Nicholas J Slusher, Charles P Daniel, Zachary Lee, Bradley Dorius, Sonnah Barrie, Tomasina Q Parker-Actlis, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kaye

“…Discovery as a key player in the development of addiction dates to the 1950s, with a study performed by Olds and Milner on rats placed in a Skinner box. Their original discovery is part of the beginning of what would become the search into the main mechanistic source of addiction, and how exactly it works at a cellular, physiological, and psychological level. …”
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VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans. by Sung Min Han, Hajer El Oussini, Jelena Scekic-Zahirovic, Jack Vibbert, Pauline Cottee, Jeevan K Prasain, Hugo J Bellen, Luc Dupuis, Michael A Miller

“…When vMSP levels drop, cytoskeletal or mitochondrial abnormalities in muscle induce elevated DAF-16, the Forkhead Box O (FoxO) homolog, transcription factor activity. …”
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Determination of Very Low Level of Free Formaldehyde in Liquid Detergents and Cosmetic Products Using Photoluminescence Method by Ali Gholami, Atefeh Mohsenikia, Saeed Masoum

“…In this study, a photoluminescence method was achieved by using 2-methyl acetoacetanilide. Also, the Box-Behnken design was applied for optimization of Hantzsch reaction for formaldehyde derivatization. …”
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Modeling the Liquid-Phase Adsorption of Cephalexin onto Coated Iron Nanoparticles Using Response Surface and Molecular Modeling by Shabnam Ahmadi, Soumya Ghosh, Alhadji Malloum, Charné Bornman, Christian Osagie, Leili Mohammadi, Chinenye Adaobi Igwegbe

“…In order to assess the interactions between process factors, the experiments involving the liquid-phase adsorption of cephalexin (CEX) onto silicon-coated iron nanoparticles (Fe3O4@SIO2) were designed using the Box-Behnken Design-Response surface methodology (BBD-RSM). …”
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Optimal Coverage Path Planning for UAV-Assisted Multiple USVs: Map Modeling and Solutions by Shaohua Pan, Xiaosu Xu, Yi Cao, Liang Zhang

“…By refining the axial, length, width, and coordinate information of obstacles, the algorithm enables YOLOv5 to generate accurate object bounding box prompts and then assists SAM in automatically and accurately extracting obstacles and coastlines in complex scenes. …”
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Push-Out Tests on Large Diameter and High Strength Welded Stud Connectors by Fei Yang, Yuqing Liu, Yongjun Li

“…Welded stud connectors, typically 19 mm and 22 mm in diameter, are usually densely arranged at the interface between the steel anchorage box and the wall of the concrete pylon to transfer the huge cable force into the concrete pylon. …”
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Curcumin inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells via IGF-1/PI3K/Akt pathway by Chao Chen, Qiwu Wang, Jiwen Liu

“…Phosphoinositide 3-kinase (PI3K), Akt, and forkhead box protein O1 (FOXO1) expression and phosphorylation were assessed by western blotting. …”
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An efficient and lightweight detection method for stranded elastic needle defects in complex industrial environments using VEE-YOLO by Qiaoqiao Xiong, Qipeng Chen, Saihong Tang, Yiting Li

“…Finally, EIoU Loss replaced CIoU Loss to address bounding box aspect ratio variability and sample imbalance challenges, significantly improving overall detection task performance. …”
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In house virtual surgery and 3D complex head and neck reconstruction by Kimberly Luu, Amirreza Pakdel, Edward Wang, Eitan Prisman

“…However, third party access to this technology is costly and removes the opportunity to design, create, and modify the bony reconstructions, as third party technology is a black box. This series is a pilot study to document the feasibility of an in-house software tool. …”
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Deep learning modeling of manufacturing and build variations on multistage axial compressors aerodynamics by Giuseppe Bruni, Sepehr Maleki, Senthil K. Krishnababu

“…Compared to traditional “black-box” surrogate models, it provides explainability to the predictions of the overall performance by identifying the corresponding aerodynamic drivers. …”
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Laryngeal cancer diagnosis based on improved YOLOv8 algorithm by Xin Nie, Xueyan Zhang, Di Wang, Yuankun Liu, Lumin Xing, Wenjian Liu

“…The larynx, also known as the voice box, plays a crucial role in voice production and ventilation. …”
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Dual Functions of the C5a Receptor as a Connector for the K562 Erythroblast-Like Cell-THP-1 Macrophage-Like Cell Island and as a Sensor for the Differentiation of the K562 Erythrob... by Hiroshi Nishiura, Rui Zhao, Tetsuro Yamamoto

“…The transcriptional nuclear factor binding to the Y box of human leukocyte antigen genes (NF-Y) for the C5a receptor (C5aR) gene is active in erythroblasts. …”
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ProACT: An Augmented Reality Testbed for Intelligent Prosthetic Arms by Shivani Guptasarma, Monroe D. Kennedy

“…We demonstrate the use of ProACT through preliminary studies, with non-amputee participants performing an adapted Box-and-Blocks task with and without intent estimation. …”
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Optimization of a fermented pumpkin-based beverage to improve Lactobacillus mali survival and α-glucosidase inhibitory activity: A response surface methodology approach by W.Y. Koh, U. Uthumporn, A. Rosma, A.R. Irfan, Y.H. Park

“…Keywords: Probiotics, Response surface methodology, Box-Behnken, Hyperglycaemia, Functional food…”
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