A Retrospective, Single-Center Assessment of Changes in Pain, Agitation, and Delirium Management Before and During the COVID-19 Pandemic by Rachel L. Winner, PharmD, BCCCP, Lydia R. Ware, PharmD, BCPS, BCCCP, Kevin M. Dube, PharmD, BCPS, BCCCP, Mary P. Kovacevic, PharmD, BCPS, BCCCP, Kenneth E. Lupi, PharmD, BCPS, BCCCP, Paul M. Szumita, PharmD, FCCM, FASHP, BCCCP, BCPS, Jeremy R. DeGrado, PharmD, BCCCP

“…This was a single-center, retrospective, pre-/post-cohort analysis of mechanically ventilated adult patients without COVID-19 infection admitted to an ICU in Boston, MA. The “pre” and “post” groups enrolled patients in 2019 and 2021, respectively. …”
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Development and Videographic Evaluation of a Vascular Access Simulation-Based Curriculum for Surgical and Medical Trainees by Alaska Pendleton, MD, MPH, Tiffany R. Bellomo, MD, Srihari K. Lella, MD, Kristen Jogerst, MD, Ada Stefanescu, MD, MSc, Douglas Drachman, MD, Nikolaos Zacharias, MD, Anahita Dua, MD, MBA, MSc

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Exploring the Complex Heliotail Boundary by an Extended Level Set Approach by C. Onubogu, M. Opher, M. Kornbleuth, G. Tóth, V. Florinski

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Are there sensitive periods for physical activity to influence the development of executive function in children? by Joseph M. Northey, Lauren B. Raine, Charles H. Hillman

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A transgenic mouse line with a 58 kb fragment deletion shows skeletal defects by Ahmed Alamoudi, Dina Husein, Yoshio Ohyama, Angela Chen, Hanna Mochida, Yoshiyuki Mochida

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Impetus of US hospital leaders to invest in patient-reported outcome measures (PROMs): a qualitative study by Andrea L Pusic, Marilyn Heng, Danny Mou, Rachel C Sisodia, Meredith B Rosenthal, Barbara Bokhour, Christer Mjåset, Claire M Sokas, Azan Virji

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Resource Utilization and Costs of Care prior to ART Initiation for Pediatric Patients in Zambia by Hari S. Iyer, Callie A. Scott, Deophine Lembela Bwalya, Gesine Meyer-Rath, Crispin Moyo, Carolyn Bolton Moore, Bruce A. Larson, Sydney Rosen

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Fibroblast Growth Factor and Mineral Metabolism Parameters among Prevalent Kidney Transplant Patients by Madhumathi Rao, Priyanka Jain, Temitope Ojo, Gautam Surya, Vaidyanathapuram Balakrishnan

“…Cross-sectional study of 106 kidney transplant patients enrolled November 2005–October 2009 at Tufts Medical Center (TMC), Boston. Results. The prevalence of hypophosphatemia was 34%, hypercalcemia 3%, and elevated PTH levels 66%, at a median (25th–75th percentile) duration of 12.8 (7.5–30.9) months post-transplant. …”
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Interdisciplinary Management of Cystic Neoplasms of the Pancreas by Linda S. Lee, Thomas Clancy, Vivek Kadiyala, Shadeah Suleiman, Darwin L. Conwell

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Immunostaining of Lgr5, an Intestinal Stem Cell Marker, in Normal and Premalignant Human Gastrointestinal Tissue by Laren Becker, Qin Huang, Hiroshi Mashimo

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Modeling the Encephalopathy of Prematurity in Animals: The Important Role of Translational Research by Hannah C. Kinney, Joseph J. Volpe

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Iatrogenic Spinal Cord Injury during Removal of the Inferior Articular Process in the Presence of Ossification of the Ligamentum Flavum by Shane M. Burke, Steven W. Hwang, Mina G. Safain, Ron I. Riesenburger

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Racial Disparities of Alcohol-Associated Liver Disease and Its Complications in Hospitalized Patients With Alcohol Use Disorder by Soo Young Hwang, Elina Stoffel, David Sooik Kim, Elizabeth Verna, Wei Zhang

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Subtyping Obsessive-Compulsive Disorder: Neuropsychological Correlates by Catherine L. Harris, Wayne M. Dinn

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Cardiac Hypertrophy and Fibrosis in the Metabolic Syndrome: A Role for Aldosterone and the Mineralocorticoid Receptor by Eric E. Essick, Flora Sam

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Ossifying Parotid Carcinoma ex Pleomorphic Adenoma by Suresh Mohan, Sidharth V. Puram, Bharat Yarlagadda, Vania Nosé, Daniel G. Deschler

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Alexithymia and Apathy in Parkinson’s Disease: Neurocognitive Correlates by Yelena Bogdanova, Alice Cronin-Golomb

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Clinical and molecular outcomes from the 5-Year natural history study of SSADH Deficiency, a model metabolic neurodevelopmental disorder by Itay Tokatly Latzer, Jean-Baptiste Roullet, Wardiya Afshar-Saber, Henry H. C. Lee, Mariarita Bertoldi, Gabrielle E. McGinty, Melissa L. DiBacco, Erland Arning, Melissa Tsuboyama, Alexander Rotenberg, Thomas Opladen, Kathrin Jeltsch, Àngels García-Cazorla, Natalia Juliá-Palacios, K. Michael Gibson, Mustafa Sahin, Phillip L. Pearl

“…Abstract Background Succinic semialdehyde dehydrogenase deficiency (SSADHD) represents a model neurometabolic disease at the fulcrum of translational research within the Boston Children’s Hospital Intellectual and Developmental Disabilities Research Centers (IDDRC), including the NIH-sponsored natural history study of clinical, neurophysiological, neuroimaging, and molecular markers, patient-derived induced pluripotent stem cells (iPSC) characterization, and development of a murine model for tightly regulated, cell-specific gene therapy. …”
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Extensive VZV Encephalomyelitis without Rash in an Elderly Man by Karen Lynch, Prakhar Agarwal, Anu Paranandi, Susan Hadley, Mithila Vullaganti

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Reshaping Our Understanding of Sensation and Pain Following Breast Reduction Surgery by Katya Remy, MD, Curtis L. Cetrulo, Jr, MD, Colby J. Hyland, MD, Riley Baker, BS, Anna Reaman, BS, Krishna Vyas, MD, PhD, Lisa Gfrerer, MD, PhD, William G. Austen, Jr, MD, Katherine H. Carruthers, MD

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