Case report: identification of novel variant in SLC26A2 gene and preimplantation genetic testing for monogenic disorders in preventing diastrophic dysplasia by Ziravard N. Tonyan, Yulia A. Nasykhova, Maria M. Danilova, Elena S. Shabanova, Olesya N. Bespalova, Igor Y. Kogan, Andrey S. Glotov

“…Abstract Background Diastrophic dysplasia is a rare autosomal recessive disorder characterized by abnormalities in bone and cartilage development, caused by pathogenic variants in the SLC26A2 gene. …”
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SDF-1α/OPF/BP Composites Enhance the Migrating and Osteogenic Abilities of Mesenchymal Stem Cells by Linli Li, Xifeng Liu, Bipin Gaihre, Sungjo Park, Yong Li, Andre Terzic, Lichun Lu

“…Thus, designed SDF-1α/OPF/BP composites were competent in promoting the homing and osteogenesis of MSCs and thus offer a promising bioactive scaffold candidate for on-demand bone tissue regeneration.…”
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Influences of multi-pass friction stir alloying on characterization of AZ91D alloy-based dual reinforcement bio-ceramic nano-composites by Surendra Kumar Patel, Guoxin Dai, Lu Liu, Zhen Sun, Lei Shi

“…Finally, this research was carried out for treatment of bone defects and fractures as well as improving corrosion resistance of the mg-containing biocompatible implants.…”
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Human in vivo talocrural contributions to ankle joint complex kinematics during walking, running, and hopping by Anja-Verena Behling, Lauren Welte, Michael J. Rainbow, Luke Kelly

“…Understanding the individual contributions of the talus and calcaneus is crucial for comprehending ankle joint complex function in healthy populations, and alterations in function that may exist in clinical conditions.To achieve accurate bone kinematics, high-resolution biplanar videoradiography was used with participants engaged in walking and running (n = 9) and hopping (n = 9) with no overlap in participants. …”
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PAC-Mediated AKI Protection Is Critically Mediated but Does Not Exclusively Depend on Cell-Derived Microvesicles by H. Dihazi, K. Schwarze, S. Patschan, G. A. Müller, O. Ritter, M. Zeisberg, D. Patschan

“…Syngeneic murine PACs were stimulated with either melatonin, angiopoietin-1 or -2, or with bone morphogenetic protein-5 (BMP-5) for one hour, respectively. …”
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Mesenchymal Stem Cell-Educated Macrophages Ameliorate LPS-Induced Systemic Response by Yaoqin Hu, Chaojin Qin, Guoping Zheng, Dengming Lai, Huikang Tao, Yan Zhang, Guanguan Qiu, Menghua Ge, Lanfang Huang, Lina Chen, Baoli Cheng, Qiang Shu, Jianguo Xu

“…Both bone marrow and adipose-derived mesenchymal stem cells (ASCs) have immunomodulatory effects. …”
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Pantoprazole Decreases Cell Viability and Function of Human Osteoclasts In Vitro by Markus Prause, Claudine Seeliger, Marina Unger, Elizabeth Rosado Balmayor, Martijn van Griensven, Alexander Tobias Haug

“…Osteoclast-specific gene expression was evaluated after seven days and revealed no significant differences between all samples. Overall, the bone degrading and resorptive function of osteoclasts is inhibited by the administration of proton pump inhibitors. …”
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Elevated Incidence of Fractures in Solid-Organ Transplant Recipients on Glucocorticoid-Sparing Immunosuppressive Regimens by B. J. Edwards, A. Desai, J. Tsai, H. Du, G. R. Edwards, A. D. Bunta, A. Hahr, M. Abecassis, S. Sprague

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ANALYSIS OF MAXILLARY FRACTURE PATIENTS PROFILE IN A TERTIARY GENERAL HOSPITAL (2018-2020) by I Dewa Gde Daniswara Suarta, Agus Santoso Budi, Rosy Setiawati, Magda Rosalina Hutagalung

“…Abstract: Introduction: The maxilla is a crucial bone in the midface, playing a significant role both functionally and cosmetically.  …”
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A case report: interstitial pneumonia following treatment of gastric cancer with sintilimab in combination with S-1 by Pei Zhu, Qingming Sun, Sheng Xu, Wanhui Dong

“…There have been cases of interstitial pneumonia caused by treatment with sintilimab or S-1 in clinical settings, but no cases of interstitial pneumonia caused by treatment with a combination of sintilimab and S-1 have been reported.Case reportA patient diagnosed with gastric cancer underwent nine courses of treatment using a chemotherapy regimen of combined oxaliplatin S-1., Due to severe bone marrow suppression and gastrointestinal adverse reactions, the treatment was switched to sintilimab in combination with S-1therapy., This change resulted in the development of interstitial pneumonia, as revealed by non-contrast chest Computed Tomography scans. …”
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Case report: A novel 11-bp deletion in exon 11 causing a frameshift in the C-terminal of the ALAS2 gene leading to X-linked sideroblastic anemia—a family study by Salam Al kindi, Salam Al kindi, Altaf Al-Mamari, Shoaib Al-Zadjali, Mohamed Al-Rawahi, Ali Al Madhani, Anil V. Pathare

“…The proband was a 29-year-old man with moderately severe microcytic hypochromic anemia with splenomegaly and increased ring sideroblasts in the bone marrow with considerable iron overload. Sanger sequencing documented a missense mutation leading to a frameshift with an elongated polypeptide of 614 AA instead of the normal 587 AA protein c.1743_1753 del (p.Gln581Hisfs*35). …”
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A Clinical Study on Functional Outcome of Percutaneous Transforaminal Endoscopic Discectomy under Local Anesthesia by Suryansh Nema, Varun Kumar Agarwal

“…Out of 16 cases of L5-S1 disc prolapse, 1 case was operated by making an iliac bone window due to the inaccessibility of disc space because of highly placed iliac crest. …”
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Recurrent Bacterial Meningitis in a Child with Mondini Dysplasia by Eda Kepenekli-Kadayifci, Ayşe Karaaslan, Serkan Atıcı, Adem Binnetoğlu, Murat Sarı, Ahmet Soysal, Gülşen Altınkanat, Mustafa Bakır

“…During the evaluation to determine the etiology of the RBM, cystic malformation in the cochlea and vestibular dilatation consistent with Mondini dysplasia were detected via computerized tomography (CT) of the temporal bone.…”
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Exploration of the diagnostic and prognostic roles of decreased autoantibodies in lung cancer by Ying Ye, Ying Ye, Yi Huang, Yi Huang, Jianbo Pan, Jianbo Pan

“…Moreover, 5 of the decreased autoantibodies can also be applied for supervising bone metastasis in lung adenocarcinoma. A follow-up process for 13 patients diagnosed with early-stage lung cancer revealed that 10 of the 15 decreased autoantibodies would recover to a higher level after the tumor was resected. …”
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Polymorphous Adenocarcinoma: A Rare Case Report with Unique Radiographic Appearance on CBCT by Jagadish Chandra, Junaid Ahmed, K. M. Veena, M. Vijayakumar, Nandita Shenoy, Nanditha Sujir

“…Panoramic radiograph taken previously had revealed evidence of alveolar bone loss in relation to the maxillary teeth and was inconclusive of any other findings. …”
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A Rare Case of Glioblastoma Multiforme with Osseous Metastases by Rubens Barros Costa, Ricardo Costa, Jason Kaplan, Marcelo Rocha Cruz, Hiral Shah, Maria Matsangou, Benedito Carneiro

“…Despite choosing no treatment, he elected to undergo a bone biopsy to understand the new underlying process. …”
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Exercise-Intervened Circulating Extracellular Vesicles Alleviate Oxidative Stress in Cerebral Microvascular Endothelial Cells Under Hypertensive Plus Hypoxic Conditions by Smara Sigdel, Shuzhen Chen, Gideon Udoh, Jinju Wang

“…Our group has recently demonstrated that exercise intervention affects the release and function of bone marrow endothelial progenitor cell-derived extracellular vesicles (EVs) in transgenic hypertensive mice. …”
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Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation by Li Chen, Kaikai Shi, Weimin Qiu, Lars Aagaard, Moustapha Kassem

“…Background. Human bone marrow stromal/stem cells (hMSCs, also known as the skeletal stem cells or mesenchymal stem cells) are being employed to study lineage fate determination to osteoblasts, adipocytes, and chondrocytes. …”
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SYNERGISTIC EFFECT OF QUERCETIN AND EPIGALLOCATECHIN-3-GALLATE AS AGENTS TO PREVENT CONNECTIVE TISSUE DISINTEGRATION IN THE PERIODONTIUM OF RATS UNDER SYSTEMIC AND LOCAL ADMINISTR... by A.M. Yelins’ka, V.O. Kostenko

“…At the same time combined use of quercetin and EGCG under experimental conditions led to the decrease in the FHP content in the alveolar bone by 24.5 and 20.2% respectively compared with values for the animals received separate quercetin and EGCG. …”
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Subacute Urinary Retention due to a Subpubic Cartilaginous Cyst Treated with Surgical Resection and Internal Fixation: A Case Report and Review of the Literature by Yu Taniguchi, Hiroshi Kamada, Hisashi Sugaya, Tomofumi Nishino, Hajime Mishima, Naoyuki Ochiai, Masashi Yamazaki

“…On physical examination, a hard, flexible, nontender mass, 4 cm in diameter, was palpable along the lower border of the pubic bone, extending to the perineum. Magnetic resonance imaging revealed a clearly distinct (3.8 cm × 3.8 cm × 7.2 cm) mass on the midpelvic side of the pelvis, centered on the pubic joint. …”
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