Integrative analysis of Ewing’s sarcoma reveals that the MIF-CD74 axis is a target for immunotherapy by Fangzhou He, Jiuhui Xu, Fanwei Zeng, Boyang Wang, Yi Yang, Jie Xu, Xin Sun, Tingting Ren, Xiaodong Tang

“…Abstract Background Ewing’s sarcoma (EwS), a common pediatric bone cancer, is associated with poor survival due to a lack of therapeutic targets for immunotherapy or targeted therapy. …”
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Research Progress on the Effect of Exercise Rehabilitation on Functional Level and Physical Fitness by YIN Lianhua, ZHENG Yan, WU Lijuan, NI Xuling, CHEN Lidian

“…The main functions include regulating blood pressure, blood lipids and blood glucose, improving balance and muscle strength,increasing bone mineral density, enhancing cardiorespiratory fitness and walking ability, improving cognitive and memory functions,regulating emotions, promoting mental health, and improving the quality of life, etc., so as to achieve the goal of shortening the process of disease rehabilitation and improving its curative effect. …”
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Incidence and Risk Factors of Infection After Fracture Fixation: A Multicenter Cohort Study by Baisheng Wang, Jingdong Zhang, Wenfeng Han, Xin Tang, Feng Tian

“…These factors included BMI ranges of 24.0–27.9 and 28.0–31.9, smoking, a high ASA score, high‐energy trauma, diabetes, open fracture, seasonal timing of the surgery (summer), bone grafting, drainage duration, surgical duration ≥ 180 min, and A/G ratio < 1.2. …”
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Aggressive Disease Course of Multiple Myeloma with Concomitant ALK-Negative Anaplastic Large Cell Lymphoma: A Case Report with an Unusual Presentation by Michela Staderini, Lara Mannelli, Elisabetta Antonioli, Benedetta Puccini, Valentina Berti, Francesco Mungai, Federica Vergoni, Valentina Carrai, Luigi Rigacci, Alberto Bosi

“…Both diseases required therapeutic intervention due to the high proliferative index of lymphoma and the presence of bone lesions attributable to myeloma. The therapeutic program initially included chemotherapy (cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone; CHOEP), radiotherapy on the leg, bortezomib, and then consolidation with autologous hematopoietic stem cell transplantation. …”
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Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome. by Brittany E Jewell, An Xu, Dandan Zhu, Mo-Fan Huang, Linchao Lu, Mo Liu, Erica L Underwood, Jun Hyoung Park, Huihui Fan, Julian A Gingold, Ruoji Zhou, Jian Tu, Zijun Huo, Ying Liu, Weidong Jin, Yi-Hung Chen, Yitian Xu, Shu-Hsia Chen, Nino Rainusso, Nathaniel K Berg, Danielle A Bazer, Christopher Vellano, Philip Jones, Holger K Eltzschig, Zhongming Zhao, Benny Abraham Kaipparettu, Ruiying Zhao, Lisa L Wang, Dung-Fang Lee

“…Transcriptome analysis of RTS osteoblasts validated decreased bone morphogenesis while revealing aberrantly upregulated mitochondrial respiratory complex I gene expression. …”
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Selected Metabolic Markers in Girls with Turner Syndrome: A Pilot Study by E. Błaszczyk, M. Lorek, T. Francuz, J. Gieburowska, A. Gawlik

“…There were no differences in chronological or bone age. No significant differences were observed in mean weight, although the Z-score BMI was higher in the study group. …”
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Concurrent Diagnosis of Chronic Myeloid Leukemia and Follicular Lymphoma: An Unreported Presentation by Amy G. Starr, Sushma R. Jonna, Joeffrey J. Chahine, Bhaskar V. Kallakury, Chaitra S. Ujjani

“…We report a case of a 73-year-old male who presented with dyspnea and right-sided lower extremity edema in the setting of leukocytosis. Bone marrow evaluation indicated a chronic phase chronic myeloid leukemia (CML), confirmed by molecular testing. …”
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A telomere-related signature for predicting prognosis and assessing immune microenvironment in osteosarcoma by Shihao Li, Lina Zhang, Haiyang Zhang

“…ObjectiveOsteosarcoma is the most common primary bone cancer with a high propensity for local invasion and metastasis. …”
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Cuproptosis related lncRNA signature as a prognostic and therapeutic biomarker in osteosarcoma immunity by Ziwei Gao, Siqi Chen, Wei Ye

“…Abstract Osteosarcoma is one of the most common malignant bone tumours in children. In this study, we aimed to construct a cuproptosis-related lncRNAs signature to predict the prognosis and immune landscape of osteosarcoma patients. …”
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A rare case of Ewing's sarcoma in a 4-year-old child treated by tumor endoprosthetics using 3D printing by Vladimir Stavrev, Luben Stokov, Petko Ganev, Georgi Georgiev

“…Orthopedic oncology surgery often requires, by its very nature, precise and often extensive resections of bone and soft tissue involved in or near the tumor mass. …”
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Energy Metabolism and Lipidome Are Highly Regulated during Osteogenic Differentiation of Dental Follicle Cells by Oliver Pieles, Marcus Höring, Sadiyeh Adel, Torsten E. Reichert, Gerhard Liebisch, Christian Morsczeck

“…Human DFCs were cultured, and osteogenic differentiation was induced by either dexamethasone or bone morphogenetic protein 2 (BMP2). Previous microarray data were reanalyzed to examine pathways that are regulated after osteogenic induction. …”
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Mendelian Susceptibility to Mycobacterial Diseases (MSMD) in a 13-Year-Old Ethiopian Girl with Autosomal Dominant Interferon Gamma Receptor 1(IFN-γ R1) Defect: A Clinical Diagnosti... by Netsanet Azene Gebeyehu, Solomie Jebessa Deribessa, Freeman Alexandra, Messay Tesfaye Demissie, W Mihretu Gebre, Aklilu Melaku Gebremariam, Dagmawit Mitiku Engliz, Tizita Yosef Kidane, Lidya Million Bekele, Abate Yeshidinber Weldetsadik

“…She had tuberculosis affecting lymph nodes, skin and soft tissue, bone and joints, the lungs, and epidural and paraspinal regions. …”
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Traumatic Ulceration of the Vestibular Mucous Membrane After Insertion of Four Mini-Implants in the Atrophied Mandible: A Case Report by Domagoj Kilić, Sanja Peršić-Kiršić, Asja Čelebić

“…One year later, almost no peri-implant marginal bone loss was observed, attached and peri-implant mucosa were healthy, and the patient was delighted.…”
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Thoracolumbar spine fracture patterns, etiologies, and treatment modalities in Jordan by Ahmad Almigdad, Sattam Alazaydeh, Mohammad Bani Mustafa, Mu'men Alshawish, Anas Al Abdallat

“…The incidence of spine fractures tends to increase with age, decreased bone density, and fall risk. In this study, we evaluated thoracolumbar fractures at a tertiary hospital in Jordan regarding their frequency, etiology, patterns, and treatment modalities. …”
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RNA-BioLens: A Novel Raspberry Pi-Based Digital Microscope With Image Processing for Acute Lymphoblastic Leukemia Detection by Angeline Dwi Sanjaya, Rachmad Setiawan, Nada Fitrieyatul Hikmah

“…Morphological examination relies on each cell type&#x2019;s consistent and defining traits, traditionally performed through blood smears and bone marrow aspiration, where cell morphology is assessed under light or digital microscopes. …”
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Assessing the quality of CKD care using process quality indicators: A scoping review. by Na Zhou, Chengchuan Chen, Yubei Liu, Zhaolan Yu, Aminu K Bello, Yanhua Chen, Ping Liu

“…The three categories included laboratory measures and monitoring of CKD progression and/or complications (monitoring of kidney markers, CKD mineral and bone disorder, anemia and malnutrition, electrolytes, and volume), use of guideline-recommended therapeutic agents (use of medications), and attainment of therapeutic targets (blood pressure, glycemia, and lipids). …”
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Accuracy and operation procedure of robotic computer-aided implant surgery by Yitian Liu, Qingqing Zheng, Zonghe Xu, Yanjun Lin, Sihui Zhang, Wenxiu Huang, Jiang Chen, Dong Wu

“…However, there remains a need to optimize robotic systems to simplify the workflow and improve their ability to recognize and respond to complex bone structures. Further clinical studies should also focus on comparing the long-term implant success rate and related complications of rCAIS with traditional approaches.…”
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Computed Tomographic Tenography of Normal Equine Digital Flexor Tendon Sheath: An Ex Vivo Study by Luca Lacitignola, Pasquale De Luca, Alessandro Guarracino, Antonio Crovace

“…Single-slice helical scans, with 5 mm thickness, spaced every 3 mm, for a pitch of 0.6, and with bone algorithm reconstruction, were performed before and after injections of contrast medium. …”
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The impact of the physicochemical properties of calcium phosphate ceramics on biocompatibility and osteogenic differentiation of mesenchymal stem cells by Yuliia Skliarenko, Volodymyr V. Kolomiiets, Volodymyr V. Balatskyi, Yuliia Galuza, Oksana S. Koryak, Larysa L. Macewicz, Tetiana P. Ruban, Sergey A. Firstov, Nataliia. V. Ulianchych, Oksana O. Piven

“…These findings underscore the promising potential of HAP-based bioceramics for bone regeneration/reconstruction. Graphical Abstract…”
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Peptide Antigen Modifications Influence the On-Target and Off-Target Antibody Response for an Influenza Subunit Vaccine by Megan C. Schulte, Adam C. Boll, Agustin T. Barcellona, Elida A. Lopez, Adam G. Schrum, Bret D. Ulery

“…The PAMs were characterized, then their immunogenicity was evaluated with bone marrow-derived dendritic cells and in mice. …”
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