Clinico-hematological and immunophenotypic profile of acute leukemia of ambiguous lineage: A four year experience from a single tertiary care centre of West India by Varnika Rai, Beena Brahmbhatt, Anurag Saha, Immanuel P. Thayakaran

“…Methods and Materials: Patients diagnosed with acute leukemia, preferably their bone marrow aspirate samples, were collected in ethylene diamine tetra-acetic acid-vial. …”
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Osteoporosis among Fallers without Concomitant Fracture Identified in an Emergency Department: Frequencies and Risk Factors by Bente Glintborg, Ulrik Hesse, Thomas Houe, Jensen Claus Munk, Jan Pødenphant, Bo Zerahn

“…These two risk factors were more frequent among fallers with osteoporosis compared to fallers with normal bone mineral density or osteopenia (previous fracture P=.044, height reduction P=.0016). …”
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Osteoarthritis-related knee pain: MRI-guided focused ultrasound ablation treatment by Christin A. Tiegs-Heiden, Zaiyang Long, Aiming Lu, Krzysztof R. Gorny, Gina K. Hesley

“…It is FDA approved for the treatment of painful bone metastases and osteoid osteoma and has been considered for the treatment of other painful conditions such as osteoarthritis. …”
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Exploring the Most Promising Stem Cell Therapy in Liver Failure: A Systematic Review by Jeanne AdiwinataPawitan

“…Among the various adult stem cells that were used in human studies, MSCs from the bone marrow or umbilical cord performed better compared to other types of adult stem cells, though no study showed a complete and sustainable performance in the outcome measures. …”
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Prophylactic intravenous immunoglobulin use in allogeneic stem cell transplantation; does intravenous immunoglobulin affect survival, sepsis, and engraftment time? by Ahmet Kaya, İlhami Berber, İrfan Kuku, Emin Kaya, Mehmet Ali Erkurt, Soykan Biçim, Süleyman Arslan, Fatma Hilal Yağin

“…MATERIALS AND METHODS: In this study, sepsis status, infection focus causing sepsis, neutrophil and platelet engraftment time of patients the length of stay in the hospital at the time of the stem cell transplant, if the patient died, how many days after the transplant the event developed, and the data of the bone marrow transplant unit were reviewed retrospectively. …”
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Iguratimod prevents renal fibrosis in unilateral ureteral obstruction model mice by suppressing M2 macrophage infiltration and macrophage–myofibroblast transition by Yueyuan Zhou, Zhilan Li, Shenyi Yu, Xuan Wang, Tingting Xie, Weiru Zhang

“…In addition, stimulating bone marrow-derived macrophages with IL-4 and/or iguratimod, or with TGF-β and iguratimod or SRC inhibitors in vitro, suggested that iguratimod mitigates the progression of renal fibrosis in UUO mice, at least in part, by inhibiting the IL-4/STAT6 signaling pathway to attenuate renal M2 macrophage infiltration, as well as by impeding SRC activation to reduce macrophage–myofibroblast transition. …”
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Visual Disturbance Caused by a Nail Gun-Induced Penetrating Brain Injury by Jin Bong Ye, Young Hoon Sul, Se Heon Kim, Jin Young Lee, Jin Suk Lee, Hong Rye Kim, Soo Young Yoon, Jung Hee Choi

“…A 36-year-old male presented with a nail that had penetrated through the occipital bone. He was alert and neurologically intact except for visual disturbance. …”
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Human Mast Cells (HMC-1 5C6) Enhance Interleukin-6 Production by Quiescent and Lipopolysaccharide-Stimulated Human Coronary Artery Endothelial Cells by Damandeep S. Walia, Mukut Sharma, Vineesh V. Raveendran, Jianping Zhou, Ram Sharma, Daniel J. Stechschulte, Kottarappat N. Dileepan

“…We examined the effect of intact human mast cells (HMC-1 5C6) and their selected mediators on interleukin-6 (IL-6) production and bone morphogenetic protein-2 (BMP-2) expression in human coronary artery endothelial cells (HCAEC) in the presence and absence of lipopolysaccharide (LPS). …”
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Diverse Effects of Phytoestrogens on the Reproductive Performance: Cow as a Model by Izabela Wocławek-Potocka, Chiara Mannelli, Dorota Boruszewska, Ilona Kowalczyk-Zieba, Tomasz Waśniewski, Dariusz J. Skarżyński

“…Finally, the soybean becomes the main source of protein in animal fodder because of an absolute prohibition of bone meal use for animal feeding in 1995 in Europe. …”
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Combination of functional dyspepsia syndrome and irritable bowel syndrome by V. T. Ivashkin, Ye. A. Poluektova

“…Patient complained of weakness, drowsiness, dizziness, attacks of subfebrile fever, accompanied by bone aching, frequent painless micturition. Patient felt sick for the first at the age of 7, deteriorations in state of health were directly related to events (or risk of events), requiring mobilization of inner forces – study at school and institute, intrafamily conflicts, individual activity, etc. …”
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Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article by Syed Faizan Mehdi, Muhammad Hamza Qureshi, Salman Pervaiz, Karishma Kumari, Edwin Saji, Mahnoor Shah, Ahmad Abdullah, Kamran Zahoor, Hafiza Amna Qadeer, Disha Kumari Katari, Christine Metz, Lopa Mishra, Derek LeRoith, Kevin Tracey, Michael J. Brownstein, Jesse Roth

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CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting. by Kelly Lim, Winnie L Kan, Pramod C Nair, Monika Kutyna, Angel F Lopez, Timothy Hercus, David M Ross, Steven Lane, Chun Yew Fong, Anna Brown, Agnes Yong, David Yeung, Timothy Hughes, Devendra Hiwase, Daniel Thomas

“…Clinically, CBL mutations were associated with increased bone marrow blasts at diagnosis, leukocytosis and splenomegaly, similar to patients harboring NRAS or KRAS mutations. …”
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Progress of research on clincal application of computer-assisted implant placement techniques for zygomatic implant placement by ZHENG Yue, ZHANG Senlin

“…A zygoma drill guide can increase the precision of zygomatic implant placement. A combined bone- and mucosa-supported static guide can facilitate optimal zygomatic implant position. …”
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Hypoxia impairs decitabine-induced expression of HLA-DR in acute myeloid leukaemia cell lines by Sam Humphries, Sean M. Burnard, Courtney D. Eggins, Simon Keely, Danielle R. Bond, Heather J. Lee

“…However, AML cells targeted by HMA therapy are often quiescent within the bone marrow, where oxygen levels are low. In this study, we investigate the effects of hypoxia on HMA responses in AML cells. …”
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Myeloma cell-derived CXCL7 facilitates proliferation of tumor cells and occurrence of osteolytic lesions through JAK/STAT3 pathway by Yue Wang, Tianwei Lan, Qiongyan Zhang, Chi Zhou, Peng Liu

“…Additionally, our mouse xenograft tumor model demonstrated that CXCL7 can induce femoral fractures and reduce bone mineral density. Concurrently, it was discovered that CXCL7 could activate the JAK/STAT3 pathway via CXCR2 and upregulate the expression levels of MMP13 and C-myc, facilitating MM cell proliferation and activation of the osteoclast signaling pathway. …”
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GRAMMAR-Lambda Delivers Efficient Understanding of the Genetic Basis for Head Size in Catfish by Yunfeng Zhao, Jin Gao, Hong Feng, Li Jiang

“…Based on the results of gene–gene interaction analysis, we speculate that there may be frequent genetic interactions between chromosome 19 and chromosome 29 in bone development. Additionally, many candidate genes, gene families, and mechanisms (such as SOCE mechanisms) affecting skeletal development and morphology have been identified. …”
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Prevalence of hypovitaminosis D in exclusive breastfed babies in first 6 months of life by Yasser A. Ahmed, Mohammed M.S. Younis, Abd E.A. Alsayed Ahmed, Esraa R.M. Ahmed

“…Conclusion Vitamin D deficiency can provoke raised parathormone hormone, which constructs the chance of bone ailments. Serum calcium and alkaline phosphatase were unequivocally related to vitamin D. …”
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A Novel Spine Fixation System Made Entirely of Carbon-Fiber-Reinforced PEEK Composite: An In Vitro Mechanical Evaluation by Ofir Uri, Yoram Folman, Gil Laufer, Eyal Behrbalk

“…The fatigue resistance, modulus of elasticity which is very similar to that of bone, radiolucency, and CT/MRI artifact-free feature of this spine fixation system made entirely of CFR-PEEK may offer advantages over traditional spine fixation systems made of metal alloys.…”
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Pharmacokinetics and Biodistribution of Zinc-Enriched Yeast in Rats by Shuangqing Zhang, Yan Zhang, Ning Peng, Haibo Zhang, Juan Yao, Zhihong Li, Liegang Liu

“…Both ZnY and ZnSO4 were slowly eliminated with a half-life of over 7 h and bone had the highest Zn level in all tissues. Compared to ZnSO4, the relative bioavailability of ZnY was 138.4%, indicating that ZnY had a significantly higher bioavailability than ZnSO4.…”
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Predictors of implant failure: A comprehensive analysis of risk factors in oral implant restoration for patients with partial defects of dentition by Dake Linghu, Danna Zhang, Min Liu

“…The analysis revealed that factors such as gender, post-implant smoking, oral hygiene status at the second-year follow-up, tooth position, number of implants, timing of loading, width of keratinized mucosa, and bone quantity significantly influenced the likelihood of implant failure (P<0.05). …”
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