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4281
The Effects of Forodesine in Murine and Human Multiple Myeloma Cells
Published 2010-01-01“…Multiple myeloma (MM) is the second most commonly diagnosed hematological malignancy, characterized by a monoclonal proliferation of malignant cells in the bone marrow. Despite recent advances in treatment strategies, MM remains incurable and new therapeutical targets are needed. …”
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4282
Initial Cytotoxicity of Mineral Trioxide Aggregate (MTA) during Setting on Human Mesenchymal Stem Cells
Published 2019-01-01“…Bone-marrow-derived human mesenchymal stem cells (hMSCs) which are important cell source for hard tissue regeneration stay near periapical lesions of tooth, playing an essential role in periodontal regeneration. …”
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4283
Identification of Osteosarcoma-Related Specific Proteins in Serum Samples Using Surface-Enhanced Laser Desorption/Ionization-Time-of-Flight Mass Spectrometry
Published 2014-01-01“…Osteosarcoma (OS) is the most common malignant bone tumor. To identify OS-related specific proteins for early diagnosis of OS, a novel approach, surface-enhanced laser desorption/ionization-time-of-flight mass spectrometry (SELDI-TOF-MS) to serum samples from 25 OS patients, 16 osteochondroma, and 26 age-matched normal human volunteers as controls, was performed. …”
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4284
Hypercalcemia, Anemia, and Acute Kidney Injury: A Rare Presentation of Sarcoidosis
Published 2015-01-01“…Our Initial impression was likely underlying hematologic malignancy such as lymphoma or multiple myeloma. A bone marrow biopsy was performed that revealed nonnecrotizing granulomatous inflammation. …”
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4285
Unleashing the Potential of Biochar Composite as Organic Nutrient Source: Implications as Soil Ameliorant, Seed Yield, and Physiological Attributes of Helianthus annuus L.
Published 2024-01-01“…However, the influence of composite biochar (C-BC) obtained from poultry feathers (PFs), cow bones (CBs), and rice straw (RS) waste streams as sources of N, P, and K, respectively, is still unclear. …”
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4286
Polyurethanes as Biomaterials in Medicine: Advanced Applications, Infection Challenges, and Innovative Surface Modification Methods
Published 2025-01-01“…PUs are employed in a diverse array of medical devices, including non-implantable applications such as wound dressings, catheters, and infusion sets; short-term implants like bone stabilizers and tracheostomy tubes; and long-term implants such as tissue regeneration scaffolds, artificial blood vessels, and heart valves. …”
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4287
Comparison between an Acrylic Splint Herbst and an Acrylic Splint Miniscrew-Herbst for Mandibular Incisors Proclination Control
Published 2014-01-01“…Some of the variables, instead, presented a significant difference such as incisor flaring, mandibular bone base position, and skeletal discrepancy. Conclusions. …”
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4288
CD4+ T Cells Mediate Dendritic Cell Licensing to Promote Multi‐Antigen Anti‐Leukemic Immune Response
Published 2025-01-01“…In vitro assays confirm the ability of CD4+ T cells from leukemia‐responsive mice to promote robust maturation of naïve bone marrow DC in the presence of non‐immunogenic leukemia antigens. …”
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4289
VOC Emissions from a Rendering Plant and Evaluation for Removal of Pentanal by Oxidization Using Hydrogen Peroxide
Published 2023-02-01“…Abstract Rendering plants treat dead livestock and produce grease and bone meal. In a rendering plant, the cooking and drying processes are the main sources of odor emissions. …”
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4290
Single cell RNA sequencing improves the next generation of approaches to AML treatment: challenges and perspectives
Published 2025-01-01“…Abstract Acute myeloid leukemia (AML) is caused by altered maturation and differentiation of myeloid blasts, as well as transcriptional/epigenetic alterations, all leading to excessive proliferation of malignant blood cells in the bone marrow. Tumor heterogeneity due to the acquisition of new somatic alterations leads to a high rate of resistance to current therapies or reduces the efficacy of hematopoietic stem cell transplantation (HSCT), thus increasing the risk of relapse and mortality. …”
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4291
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4292
Pattern of Thyroid Disorders in a Tertiary Care Centre of a High-Altitude Region of Nepal: A hospital-based retrospective study
Published 2024-12-01“…Untreated, these disorders can lead to severe health complications such as heart problems, pregnancy complications, goiter, bone health issues, etc. Jumla, a high-altitude Himalayan region in Nepal, includes iodine-deficient areas, making it prone to thyroid disorders. …”
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4293
Satisfactory Functional Outcome and Significant Correlation with the Length of Haglund’s Deformity after Endoscopic Calcaneoplasty: A Minimum 4-Year Follow-Up Study
Published 2022-01-01“…There was a statistically significant correlation between clinical scores (AOFAS and VAS) and the final postoperative length of the bone above parallel pitch lines (PPLs). The patients were satisfied and returned to their previous activities without reporting major morbidities except one patient who had mild pain with exertion. …”
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4294
Oxidative Stress and Cytoskeletal Reorganization in Hypertensive Erythrocytes
Published 2024-12-01“…We have previously documented physiological and morphological changes across various blood and bone marrow cell lineages, all of which exhibit elevated oxidative stress. …”
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4295
A potential VEGF-driven hypothesis of calvarial centripetal proliferation in cerebral proliferative angiopathy
Published 2025-01-01“…Calvarial thickening was present in 43.8% of cases, predominantly affecting the frontal bone, and extending bilaterally. A trend toward calvarial thickening was observed in patients with concomitant signs of cerebral venous congestion (p = 0.06), while no significant association with age, sex, or symptoms was found. …”
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4296
TUBERCULOUS ARTHRITIS OF THE ANKLE MIMICKING SYNOVITIS IN CHILD - A CASE REPORT
Published 2020-10-01“…Discussion: Radiologic examination revealed peripheral osseous erosions, reduced bone mineral content, and soft tissue swelling. A Mantoux test was positive with 15 mm induration and 25 mm erythema. …”
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4297
A Novel Mutation of the Calcium-Sensing Receptor Gene Causing Familial Hypocalciuric Hypercalcemia Complicates Medical Followup after Roux-en-Y Gastric Bypass: A Case Report and a...
Published 2019-01-01“…Eventually the patient developed elevated alkaline phosphatase, a further increased PTH and a decreased DXA T-score indicating calcium deficiency and bone resorption. As a supplement, all CaSR-mutations found at our hospital, 2005-2018.…”
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4298
Pivotal Cytoprotective Mediators and Promising Therapeutic Strategies for Endothelial Progenitor Cell-Based Cardiovascular Regeneration
Published 2016-01-01“…In response to ischemic injury signals, EPCs located in a bone marrow niche migrate to injury sites and form new vessels by secreting various vasculogenic factors including VEGF, SDF-1, and FGF, as well as by directly differentiating into endothelial cells. …”
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4299
Massive Neurilemoma of the Hard Plate in Which Preoperative Diagnosis Was Difficult
Published 2015-01-01“…The mass was a solid tumor associated with resorption of surrounding bone and expansion of the greater palatine canal. …”
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4300
Hematopoietic Stem and Progenitor Cell Expansion in Contact with Mesenchymal Stromal Cells in a Hanging Drop Model Uncovers Disadvantages of 3D Culture
Published 2016-01-01“…Here, we describe a simplified 3D hanging drop model for the coculture of cord blood-derived CD34+ hematopoietic stem and progenitor cells (HSPCs) with bone marrow-derived mesenchymal stromal cells (MSCs). …”
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