Leishmania mexicana: Novel Insights of Immune Modulation through Amastigote Exosomes by Laura Enedina Soto-Serna, Mariana Diupotex, Jaime Zamora-Chimal, Adriana Ruiz-Remigio, José Delgado-Domínguez, Rocely Buenaventura Cervantes-Sarabia, Adriana Méndez-Bernal, Alma Reyna Escalona-Montaño, María Magdalena Aguirre-García, Ingeborg Becker

“…The incubation of aExo with bone marrow-derived macrophages (BMMs) infected with L. mexicana led to their internalization and were found to colocalize with the cellular tetraspanin CD63. …”
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From fear to food: predation risk shapes deer behaviour, their resources and forest vegetation by Martin, Jean-Louis, Chamaillé-Jammes, Simon, Salomon, Anne, Gomez Pourroy, Devana Veronica, Schlaeflin, Mathilde, Le Saout, Soizic, Lucas, Annick, Bentaleb, Ilham, Chollet, Simon, Pattison, Jake, Martin-Blangy, Soline, Gaston, Anthony James

“…Because these deer also forage in the intertidal, a habitat hypothetically more exposed to risk, we also analysed how risk affected intertidal foraging by measuring the proportion of marine versus terrestrial stable isotopes in deer bone collagen. In the absence of risk, deer had a strong negative effect on understory vegetation cover and plant composition. …”
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Shaoyao Gancao decoction alleviates paclitaxel-induced cognitive impairment by activating PTEN/PI3K/AKT pathway to inhibit NETs formation by Xu Ying, Su Yue, Hu Yuwen, Li Xiang, Zhou Ziyan, Yuan Ningning, Ji Xiaowei, Jiang Ruoyu, Wang Wenzhu, Zhang Yafeng, Zhai Guojie, Cheng Xiaolan

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Body morphometric measurements of Azakheli buffaloes: A neglected animal genetic resource of Pakistan by S. Rahman, I. Zahoor, R. Amjad, A. Basheer

“…The body morphometric measurements of 220 adult (33 males and 187 females) animals were taken, in centimeters, for 26 different biometric parameters, including chest girth (CG), body length (BL), barrel depth (BD), height-at-withers (HW), hip height (HH), face length (FL), face width (FW), ear length (EL), ear width (EW), horn length (HL), horn circumference (HC), neck length (NL), neck width (NW), rump length (RL), rump width (RW), thurl width (TW), tail length (TL), tail circumference (TC), pin-bone distance (PBD), fore-teat length (FtL), fore-teat circumference (FtC), rear-teat length (RtL), rear-teat circumference (RtC), testes length (TesL), testes width (TesW), and scrotal circumference (SC) with the help of a measuring tape and scale. …”
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Comparative analysis of unicortical vs. subchondral locking screws in osteoporotic proximal humerus fractures by Mohammad Khak, Jeffrey J. Olson, Patrick Williamson, Mohammad Javad Shariyate, Ahmad Hedayatzadeh Razavi, Kaveh Momenzadeh, Mohammadreza Abbasian, Nadim Kheir, Edward K. Rodriguez, Ara Nazarian

“…Methods: Using dual-energy X-ray absorptiometry (DXA), cadaveric shoulder specimens from eight female Caucasian donors with comparable bone mineral densities were used for the study. Either unicortical or bicortical locking screws (the latter representing subchondral screws in real surgeries) were utilized to fix locking plates. …”
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Characterization and Study of Gene Expression Profiles of Human Periodontal Mesenchymal Stem Cells in Spheroid Cultures by Transcriptome Analysis by Takenori Suga, Michihiko Usui, Satoru Onizuka, Kotaro Sano, Tsuyoshi Sato, Kohji Nakazawa, Wataru Ariyoshi, Tatsuji Nishihara, Keisuke Nakashima

“…However, genes involved in the negative regulation of cell proliferation, histone deacetylation, and bone morphogenetic protein signaling were strongly expressed in the spheroid culture group. …”
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Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail by Lorena V. Cortés-Medina, Herminia Pasantes-Morales, Alejandro Aguilera-Castrejon, Arturo Picones, Cesar O. Lara-Figueroa, Enoch Luis, Juan Jose Montesinos, Victor A. Cortés-Morales, M. P. De la Rosa Ruiz, Erika Hernández-Estévez, Laura C. Bonifaz, Marco Antonio Alvarez-Perez, Gerardo Ramos-Mandujano

“…MSCs can be obtained from many different sources, and the present study compares the potential of neuronal transdifferentiation in MSCs from adult and neonatal sources (Wharton’s jelly (WhJ), dental pulp (DP), periodontal ligament (PDL), gingival tissue (GT), dermis (SK), placenta (PLAC), and umbilical cord blood (UCB)) with a protocol previously tested in bone marrow- (BM-) MSCs consisting of a cocktail of six small molecules: I-BET151, CHIR99021, forskolin, RepSox, Y-27632, and dbcAMP (ICFRYA). …”
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Propolis mouthwashes efficacy in managing gingivitis and periodontitis: a systematic review of the latest findings by Muhammed Al-Huda Ballouk, Mohamed Altinawi, Abeer Al-Kafri, Talar S. Zeitounlouian, Piotr S. Fudalej

“…Abstract Background and objectives Gingivitis and periodontitis are common periodontal diseases that can significantly harm overall oral health, affecting the teeth and their supporting tissues, along with the surrounding anatomical structures, and if left untreated, leading to the total destruction of the alveolar bone and the connective tissues, tooth loss, and other more serious systemic health issues. …”
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Immunosuppressive therapy and nutritional diseases of patients after kidney transplantation: a systematic review by Aleksandra Anna Kajdas, Marcin Kleibert, Anne Katrine Normann, Krzysztof Krasuski, Ditte Søndergaard Linde, Dorota Szostak-Węgierek

“…Finally, mammalian target of rapamycin (mTOR) inhibitors was associated with bone status and mycophenolate mofetil was linked to Vitamin B12 deficiencies. …”
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Clinical Presentation and Course of Pulmonary Involvement in Chronic Nonbacterial Osteomyelitis by Toni Hospach, Friederike Blankenburg, Anita Heinkele, Kristina Rücklová, Peter Müller‐Abt, Frank Weller‐Heinemann, Laura Buchtala, Jan Maier, Jasmin Kümmerle‐Deschner, Christiane Reiser, Ales Janda, Andreas Urban, Reiner Berendes, Andrea Skrabl‐Baumgartner, Jürgen Brunner, Ralf Trauzeddel, Johannes Peter Haas, Annette Holl‐Wieden, Henner Morbach, Anja Schnabel, Normi Brück, Gabriele Hahn, Wolfgang Emminger, Isabella Valent, Regine Borchers, Christian Klemann, Ilias Tsiflikas, Jens Klotsche, Kirsten Minden, Christian M. Hedrich, Thekla von Kalle

“…Among patients with CNO, pulmonary involvement was more common in girls (91% vs 62.8%, P = 0.006) and patients with multifocal bone lesions (95% vs 65%, P <0.001) but was not associated with systemic inflammation or additional organ involvement. …”
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Gambaran Hitung Jenis Leukosit pada Pasien Penyakit Paru Obstruktif Kronik yang Dirawat di RSUP Dr. M. Djamil Padang by Revi Sofiana Martantya, Ellyza Nasrul, Masrul Basyar

“…Cigarette smoke, air pollution, and recurrent infections in the respiratory tract can activates alveolar macrophages to release inflammatory mediators that stimulate granulocytic and monocytic progenitors in the bone marrow that can affect leukocyte counts in peripheral blood. …”
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Harnessing genomic and bioinformatic data to broaden understanding of leukaemia across continents by Gumelar Gugun, Ulfa Mia Maria, Amukti Danang Prasetyaning, Irham Lalu Muhammad, Yuliani Sapto, Adikusuma Wirawan, Khairi Sabiah, Darmawi Darmawi, Chong Rockie, Ates Ilker, Singh Dilpreet, Chavan Aditya Ashok

“…Background/Aim: Leukaemia is a malignant disease of blood cells found in the bone marrow, which can be divided into acute lymphocytic leukaemia and myelocytic leukaemia. …”
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Measurable residual disease as predictor of post–day +100 relapses after allografting in adult AML by Naveed Ali, Megan Othus, Eduardo Rodríguez-Arbolí, Corentin Orvain, Filippo Milano, Brenda M. Sandmaier, Chris Davis, Ryan S. Basom, Frederick R. Appelbaum, Roland B. Walter

“…To examine the role of MFC MRD testing to predict later relapses, we examined 935 adults with AML or myelodysplastic neoplasm/AML transplanted in first or second morphologic remission who underwent bone marrow restaging studies between day 70 and 100 after HCT and were alive and without relapse by day +100. …”
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Bilateral synchronous UBE for unilateral laminotomy and bilateral decompression as a potentially effective minimally Invasive approach for two-level lumbar spinal stenosis by Yulin Zhao, Yingjun Guo, Xin Pan, Hao Li, Xianlei Gao, Haipeng Si, Wanlong Xu

“…Furthermore, as the posterior bone and soft tissue structures need to be extensively resected during the surgery, epidural scar and nerve compression are highly likely after the surgery. …”
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EULAR standardised training model for ultrasound-guided, minimally invasive synovial tissue biopsy procedures in large and small joints by Annamaria Iagnocco, Andrew Filer, Gabriel Herrero-Beaumont, Peter Balint, Ingrid Moller, Esperanza Naredo, Lene Terslev, Alessandra Bruns, Aurélie Najm, Ana Rodriguez, Raquel Largo, Stefano Alivernini, Jesús Garrido, Maria Antonietta D’Agostino, Jacqueline Uson, Juhani Koski, Maribel Miguel, Carlos Guillén-Astete, David A. Bong, George A.W. Bruyn, Carlos Acebes

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Effect of Dietary Vitamin C Ascorbic Acid on the Growth Performance and Immune Response of Betok Anabas testudineus Bloch by . Sunarto, . Suriansyah, . Sabariah

“… Vitamin C has a function for increasing normal growth, preventing bone annomaly for seed health or reducing stress, accelerating wound recovery and improving immune system against bacterial infection. …”
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Serious Bacterial Infections and Hepatitis C Virus Among People Who Inject Drugs: A Syndemic or Intertwined Epidemics? by Thomas J. Stopka, Robin M. Nance, L. Sarah Mixson, Hunter Spencer, Judith I. Tsui, Judith M. Leahy, Mai T. Pho, Jean DeJace, Judith Feinberg, April M. Young, Wei-Teng Yang, Amelia Baltes, Eric Romo, Randall T. Brown, Kerry Nolte, William C. Miller, William A. Zule, Wiley D. Jenkins, Joseph A. Delaney, Peter D. Friedmann

“…Limited research has examined the possible synergistic interrelationships between serious bacterial infections (SBIs) of the heart (i.e., endocarditis), bone, spine, brain, or joints (e.g., osteomylelitis) and hepatitis C virus (HCV) infections. …”
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Arginase-1-specific T cells target and modulate tumor-associated macrophages by Mads Hald Andersen, Inés Lecoq, Ayako Wakatsuki Pedersen, Evelina Martinenaite, Shamaila Munir Ahmad, Maria Perez-Penco, Lucia Lara de la Torre, Marion Chapellier, Lars Rønn Olsen, Mia Aaboe-Jørgensen, Hannah Jorinde Glöckner, Anne Mette Askehøj Rømer

“…In the present study, we investigated how Arg1-specific T cells can directly target TAMs and influence their polarization.Methods Murine Arg1-specific CD4+T cells isolated from splenocytes of animals vaccinated with an Arg1-derived peptide in the adjuvant montanide were co-cultured with either in vitro M2-differentiated bone marrow-derived macrophages or ex vivo isolated F4/80+TAMs. …”
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TNF-α Induced the Enhanced Apoptosis of Mesenchymal Stem Cells in Ankylosing Spondylitis by Overexpressing TRAIL-R2 by Zhenhua Liu, Liangbin Gao, Peng Wang, Zhongyu Xie, Shuizhong Cen, Yuxi Li, Xiaohua Wu, Le Wang, Hongjun Su, Wen Deng, Shan Wang, Deng Li, Jinteng Li, Yi Ouyang, Yanfeng Wu, Huiyong Shen

“…The present study aims to assess the apoptosis of bone marrow-derived ASMSCs and to investigate the underlying mechanisms of altered ASMSCs apoptosis. …”
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Sporadic Burkitt Lymphoma First Presenting as Painful Gingival Swellings and Tooth Hypermobility: A Life-Saving Referral by Erofili Papadopoulou, Maria Kouri, Dimitrios Velonis, Anastasia Andreou, Maria Georgaki, Spyridon Damaskos, Evangelia Piperi, Konstantina Delli, Ioannis K. Karoussis, Antonia Vlachou, Georgia Avgerinou, Antonis Kattamis, Nikolaos G. Nikitakis

“…The patient underwent a full staging work-up, revealing bone marrow involvement and widespread disease. A multi-chemotherapy regimen was initiated with the regression of oral lesions and symptoms within a few weeks and complete disease remission after nine chemotherapy cycles. …”
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