Taphonomic and ecological insights from conspecific bite marks on Otodus megalodon teeth by Stephen J. Godfrey, Mark Bennett, Victor J. Perez

“…Although there is now good representation of shark-bitten bone in the fossil record, shark-bitten shark teeth are still exceedingly rare. …”
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Studies on the Pinctada fucata BMP-2 Gene: Structural Similarity and Functional Conservation of Its Osteogenic Potential within the Animal Kingdom by Akiko Takami, Hirotaka Kato, Ryousuke Takagi, Tomoyuki Miyashita

“…Bone morphogenetic protein (BMP)-2 plays an important role in morphogenesis in both vertebrates and invertebrates. …”
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Proximate, Mineral Contents and Physicochemical Properties of <i>Chrysophyllum Albidum</i> (African Star Apple) Kernel Flour and Oil by S.S. Audu, C.I. Beetseh, D.U. Edward-Ekpu, A.A. Ewuga

“…The Calcium-Potassium Ratio indicates the flour is a good source of calcium for bone formation. The Physicochemical analysis showed the oil has an Acid Value of 33.12±0.25 mgKOH/g, a Saponification Value of 184.90±0.29 mgKOH/g, an Iodine Value of 60.05±0.02 mgKOH/g, a Free Fatty Acid Value of 16.05±0.14 mgKOH/g, Peroxide Value of 2.10±0.10 m Eq/kg, Moisture of 3.36±0.08 %, Unsaponifiable Matter of 5.26±0.05 g/kg and an Ester Value of 151.78±0.15 mgKOH/g. …”
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Effect of Aloe Vera mouthwash on moderate gingivitis: Clinical and microbiological study by Lana Slewa Ishaq, Amal Hanna Aziz

“… Background and objectives: Gingivitis is an inflammatory process confined to the gingiva with no attachment or bone loss, Aloe Vera (AV) is an ancient medicinal plant that is widely known for its medicinal uses. …”
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Human Neonatal Thymus Mesenchymal Stem Cells Promote Neovascularization and Cardiac Regeneration by Shuyun Wang, Shan Huang, Lianghui Gong, Zhize Yuan, Joshua Wong, Jeffrey Lee, Ming-Sing Si

“…We found that ntMSCs expressed and secreted the proangiogenic and cardiac regenerative morphogen sonic hedgehog (Shh) in vitro more than patient-matched bone-derived MSCs. We also found that organoid culture of ntMSCs stimulated Shh expression. …”
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Therapeutic Mechanism and Effect of Camptothecin on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice by Yizhuo Wang, Kunjian Liu, Zhiyong Qi, Tong Chen, Wei Yu, Yang Jiang, Guofeng Li, Huijie Xiao

“…It possesses various antitumor activities and is mainly used in the treatment of colon, ovarian, liver, and bone cancers as well as leukemia. CPT inhibits the expressions of inflammatory genes and can prevent death from chronic inflammation. …”
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Clinical and Radiological Outcomes of Extracorporeal Shock Wave Therapy in Early-Stage Femoral Head Osteonecrosis by Abdulrahman D. Algarni, Hassan M. Al Moallem

“…MRI revealed significant resolution of bone marrow edema (p<0.003). Regression was observed in 9 lesions (42.9%) and progression in 1 lesion (4.7%); no change was observed in the remaining 23 lesions (52.4%). …”
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Transplanted Endothelial Progenitor Cells Improve Ischemia Muscle Regeneration in Mice by Diffusion Tensor MR Imaging by Xin-Gui Peng, Yingying Bai, Judy R. James, Darya P. Shlapak, Shenghong Ju

“…This study investigated the feasibility and accuracy of using the DTI to evaluate effectiveness of EPCs treatment. Mouse bone marrow-derived EPCs were isolated, cultured, characterized, and transplanted to hindlimb ischemia mice model. …”
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A Massive Extradural Hematoma in Sickle Cell Disease and the Importance of Rapid Neuroimaging by Per Ole Iversen, Mboka Jacob, Jamila Makame, Mclean Abisay, Mbonea Yonazi, Anna Schuh, Julie Makani

“…Three months after evacuation of the hematoma, neuroimaging showed evidence of brain atrophy and the previously reported cerebral infarcts and multifocal bone infarction, but no vasculopathy. Possibly, disruption of the skull cortex with subsequent bleeding caused the EDH. …”
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Therapeutic Benefit in Rheumatoid Cachexia Illustrated Using a Novel Primary Human Triple Cell Coculture Model by Tracey Ollewagen, Gareth S. Tarr, Kathryn H. Myburgh, Helmuth Reuter, Carine Smith

“…This study aimed at determining differences in the cellular responses in a novel human primary cell triple coculture model exposed to serum collected from nonarthritic controls (NC), RA treatment naïve (RATN), and RA treatment-nonresponding (RATNR) patients. Bone morphogenetic protein-7 (BMP-7) was investigated as a treatment option. …”
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The effect of space flight on genes expression in brain by A. S. Tsybko, T. V. Ilchibaeva, N. K. Popova

“…In search of underlying mechanisms, many experimental tools have been developed, ranging from microgravity modeling on Earth to space flight investigations, part of which is to study the expression of genes and proteins. Unlike bone and muscle tissue, molecular changes in nerve cells during spaceflight are practically unexplored. …”
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Pattern of Thyroid Disorders in a Tertiary Care Centre of a High-Altitude Region of Nepal: A hospital-based retrospective study by Tirtha Narayan Sah, Anuraj Anu, Binamra Bista

“…Untreated, these disorders can lead to severe health complications such as heart problems, pregnancy complications, goiter, bone health issues, etc. Jumla, a high-altitude Himalayan region in Nepal, includes iodine-deficient areas, making it prone to thyroid disorders. …”
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Extramedullary Hematopoiesis in Uterine Leiomyoma Associated with Numerous Intravascular Thrombi by Xiaoyan Cui, Deniz Peker, Heather O. Greer, Michael G. Conner, Lea Novak

“…A 29-year-old nulliparous female presented with heavy vaginal bleeding and a hematocrit of 22%. No bone marrow biopsy has been performed. She had a history of uterine leiomyomata and menorrhagia for a year. …”
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Regulatory Role of the RUNX2 Transcription Factor in Lung Cancer Apoptosis by Camila Bernal, Andrea Otalora, Alejandra Cañas, Alfonso Barreto, Karol Prieto, Martin Montecino, Adriana Rojas

“…Current studies have confirmed that RUNX2 is closely related to the proliferation, invasion, and bone metastasis of multiple cancer types, such as osteosarcoma, breast cancer (BC), prostate cancer, gastric cancer, colorectal cancer, and lung cancer. …”
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Differential Proteomic Analysis Predicts Appropriate Applications for the Secretome of Adipose-Derived Mesenchymal Stem/Stromal Cells and Dermal Fibroblasts by Stefania Niada, Chiara Giannasi, Alice Gualerzi, Giuseppe Banfi, Anna Teresa Brini

“…This approach led to the recognition of distinct functions related to the conditioned medium of ASCs and DFs, with the former being involved in the regulation of neuronal death and apoptosis and the latter in bone metabolism and ossification. The proosteogenic effect of DF secretome was validated in vitro on human primary osteoblasts, providing a proof of concept of its osteoinductive potential. …”
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Oral manifestations of multiple myeloma – A systematic review by Padmajaa Krishnan, Madhu Narayan, Bose Divya, T Dinesh Kumar, A Ramesh Kumar, Rajkumar Krishnan

“…Pertaining to oral cavity 35 % of patients with symptomatic MM present with lytic bone lesions of jaws. In this systematic review we aim to study the various presentations of MM involving different sites of the oral cavity and variations in their clinical appearance providing a broader picture of the disease and enables us to prepare an early diagnostic workup.…”
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Full study of characteristics of morphological adaptations in response to chronic exercise across musculoskeletal tissues: A systematic review by Felix León, Andres Mestre, Lorelu Priego, Juan Carlos Vera

“…After removal of duplicates, title and abstract screening and full-text review, 67 records were included in the final analysis (6 for inter-vertebral disc, 6 for cartilage, 36 for bone, 2 for ligament, 9 for tendon and 7 for muscle). …”
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Vacuum Assisted Closure Therapy versus Standard Wound Therapy for Open Musculoskeletal Injuries by Kushagra Sinha, Vijendra D. Chauhan, Rajesh Maheshwari, Neena Chauhan, Manu Rajan, Atul Agrawal

“…A free flap was needed to cover exposed bone and tendon in one case in standard wound therapy group. …”
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Pharmacokinetics of PEGylated Recombinant Human Erythropoietin in Rats by Xiaohan Cao, Zhiyong Chen, Zhuoran Yu, Yonghong Ge, Xianyin Zeng

“…In in vivo half-life time measured after 125I-PEG-rHuEPO administration at the doses of 1, 2, and 3 μg/kg, t1/2α was 1.90, 1.19, and 2.50 hours, respectively, whereas t1/2β was 22.37, 26.21, and 20.92 hours, respectively; at 8, 24, and 48 hours after intramuscular administration, PEG-rHuEPO was distributed to all of the examined tissues, however, with high concentrations of radioactivity, only in plasma, blood, muscle at the administration site, and bone marrow. Following a 2 μg/kg single intramuscular administration, approximately 21% of the radiolabeled dose was recovered after almost seven days of study. …”
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Pediatric trapdoor fracture of the orbital floor with Tear-Drop sign: A case report by Zakariae Hakkou, Zainab El Zouiti, Fahd Elayoubi, Adil Abdenbi Tsen

“…Orbital trapdoor fractures are a unique type of blowout fracture seen predominantly in children due to their elastic bone structure, which predisposes to soft tissue entrapment and symptoms such as diplopia. …”
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