A 2-decade survival from a double hemolytic disease: A case of paroxysmal nocturnal hemoglobinuria with hemoglobinopathy by Aria Namiq Chaqmachi, Brwa Ali Hussein

“…Due to a mutation in the phosphatidylinositol glycan class A (PIGA) gene, hemolytic anemia, thrombosis, and bone marrow failure are the hallmarks of the uncommon hematologic illness known as paroxysmal nocturnal hemoglobinuria (PNH). …”
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Clostridial myonecrosis. A Case Report by Ledys Pérez Morales, Hidaleysi Quintana Hernández, Jorge E. Barletta del Castillo

“…A case report of a female patient who had an accident with an agricultural implement, suffering proximal third tibial fracture with loss of the continuity of the bone in the right leg is presented. She underwent surgery and antibiotic therapy. …”
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A Region-Based Statistical Shape Modeling on the First Trapezoid-Metacarpal by Lin Fu, Kaczmarek Łukasz, Ci Jiang, Yaodong Gu

“…We indicated the morphological differences of the first trapezoid-metacarpal (TMC) bone between the region-based statistical shape model (rSSM) and the nonregion-based statistical shape model (nrSSM). …”
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A case of extraskeletal chondroma in the left inguinal region by Alexey Shabunin, Ivan Lebedinsky, David Dolidze, Zurab Bagatelia, Ekaterina Solomonova, Anna Bumbu, Serghei Covantsev

“…A distinctive feature of these tumors is that they develop in soft tissues away from bone and cartilage. Extraskeletal chondromas account for 1.5% of benign soft tissue tumors. …”
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Are female athlete specific health considerations being assessed and addressed in preparticipation examinations? A scoping review and proposed framework by Jenna M. Schulz, Lois Pohlod, Samantha Myers, Jason Chung, Jane S. Thornton

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D-mannose alleviates chronic periodontitis in rats by regulating the functions of neutrophils by Xue Li, Xueting Chen, Qingyu Zhu, Pengye Zhang, Shunxue Nan, Lei Lv, Shengcai Qi

“…To evaluate the protective effects of D-mannose against periodontal bone loss, methylene blue staining, hematoxylin and eosin (H&E) staining, and micro-CT scanning were utilized. …”
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Safety and efficacy of CD33-targeted CAR-NK cell therapy for relapsed/refractory AML: preclinical evaluation and phase I trial by Ruihao Huang, Xiaoqi Wang, Hongju Yan, Xu Tan, Yingying Ma, Maihong Wang, Xiao Han, Jia Liu, Li Gao, Lei Gao, Guangjun Jing, Cheng Zhang, Qin Wen, Xi Zhang

“…No grade 3–4 adverse events were observed, except bone marrow suppression, which was relieved within one month. …”
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Effect of zinc level and the thermal environment on the zootechnical performance and tibia-breaking strength of Japanese quails by Luiz Arthur dos Anjos Lima, Thiago de Assis Moraes, Larissa Kellen da Cunha Morais, Mikael Leal Cabral Menezes de Amorim, Tarsys Noan Silva Veríssimo, José Danrley Cavalcante dos Santos, Maria Isabelly Leite Maia, Severino Guilherme Caetano Gonçalves dos Santos, Fernando Guilherme Perazzo da Costa, Ricardo Romão Guerra, Lucas Rannier Ribeiro Antonino Carvalho, Edilson Paes Saraiva

“…Japanese quails (Coturnix coturnix japonica) are sensitive to zinc (Zn) deficiency, a mineral essential for growth, development, and bone health. This study evaluated the effects of different levels of Zn in the diet on zootechnical performance, organ and carcass weight, and tibial breakage resistance in quails from 1 to 42 days of age. …”
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Lack of Hypoxia Inducible Factor-1α Influences on Macrophages Ability to Deal with Leishmania braziliensis In Vitro and Affects Pathology In Vivo by Rodrigo C.O. Sanches, Leonardo G. Vaz, Fabio V. Marinho, Erika S. Guimarães, Edgar M. Carvalho, Lucas P. Carvalho, Sergio C. Oliveira

“…In this study, we demonstrated that the parasite induces HIF-1α expression and stabilization in bone marrow–derived macrophages only when added with exogenous IFN-γ plus lipopolysaccharide. …”
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Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics by Haruno Oku, BS, Saki Yoshida, BS, Takumi Hotta, BS, Hirohito Muroi, BS, Keizo Fukushima, PhD, Kei Irie, PhD, Tatsuya Hirano, BS, Yoshimitsu Shimomura, MD, Takayuki Ishikawa, MD, PhD, Hiroaki Ikesue, PhD, Nobuyuki Muroi, PhD, Tohru Hashida, PhD, Nobuyuki Sugioka, PhD

“…In this study, we evaluated the influence of the conditioning regimen (myeloablative and reduced-intensity conditioning) or donor source (cord blood, bone marrow, and peripheral blood stem cells) on the pharmacokinetics of tacrolimus in patients undergoing HSCT, including those undergoing CBT. …”
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ASSOCIATION BETWEEN LEUKEMIC EVOLUTION AND UNCOMMON CHROMOSOMAL ALTERATIONS IN PEDIATRIC MYELODYSPLASTIC SYNDROME by Viviane Lamim Lovatel, Beatriz Ferreira da Silva, Eliane Ferreira Rodrigues, Maria Luiza Rocha da Rosa Borges, Rita de Cássia Barbosa Tavares, Ana Paula Silva Bueno, Elaine Sobral da Costa, Terezinha de Jesus Marques, Teresa de Souza Fernandez

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Macrophage-related inflammatory responses to degradation products of biodegradable molybdenum implants by Danyang Liu, Jiahao Chen, Jiannan Zhou, Jingtao Dai, Haotian Qin, Guojiang Wan, Junyu Qian, Ping Li, Jiang Li

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Defective Slc7a7 transport reduces erythropoietin compromising erythropoiesis by Judith Giroud-Gerbetant, Fernando Sotillo, Gonzalo Hernández, Irene Ruano, David Sebastián, Joana Fort, Mayka Sánchez, Günter Weiss, Neus Prats, Antonio Zorzano, Manuel Palacín, Susanna Bodoy

“…We analyzed erythropoiesis in these mice and performed bone marrow transplantation experiments to assess the role of Slc7a7 in erythroblasts and myeloid cells. …”
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Systematic Evaluation of Clinical Efficacy of Shiyiwei Shenqi (Ginseng and Astraglus, Eleven Ingredients) Preparation in Adjuvant Chemotherapy for Malignant Tumor by Bowei HUANG, Yuhui ZENG, Lisha LU, Huijuan GAN

“…Outcome indicators were: clinical efficacy (effective rate, stability rate), karnofsky performance scale, bone marrow suppression (white blood cells, hemoglobin), gastrointestinal reactions (nausea, vomiting), liver and renal function, etc.Results:A total of nine RCTs were included, including 633 patients, with 318 cases in the experimental group, 315 cases in the control group. …”
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Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats by Tetsuya Tomita, Hiromi Rakugi, Hiroki Hayashi, Ryuichi Morishita, Jiao Sun, Yuka Yanagida, Shota Yoshida, Satoshi Baba, Akiko Tenma, Masayoshi Toyoura, Sotaro Kawabata, Takako Ehara, Ryoko Asaki, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Hironori Nakagami

“…X-ray and histological analyses showed that enthesitis, bone destruction and new bone formation were inhibited by the IL17A vaccine. …”
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Medial Condyle Fracture (Kilfoyle Type III) of the Distal Humerus with Transient Fishtail Deformity after Surgery by Motoki Sonohata, Takema Nakashima, Hiroaki Suetsugi, Masaru Kitajima, Masaya Ueno, Masaaki Mawatari

“…As occurred in the current case, the bone remodeling and the improvement of ischemia of the trochlea after medial condyle fracture may be associated with the likelihood of recovery from transient “fishtail deformity.”…”
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Dentinal Dysplasia Type I: A Case Report with a 6-Year Followup by Sezin Ozer, Bora Ozden, Feyza Otan Ozden, Kaan Gunduz

“…In the radiographic examination, it was determined that some of the unerupted permanent teeth of the patient had short, blunted, and malformed roots with obliterated pulp chambers, although the bone below the teeth showed well-defined margins. …”
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Osteoblastic and Vascular Endothelial Niches, Their Control on Normal Hematopoietic Stem Cells, and Their Consequences on the Development of Leukemia by Bella S. Guerrouahen, Ibrahim Al-Hijji, Arash Rafii Tabrizi

“…The osteoblastic niche localized at the inner surface of the bone cavity might serve as a reservoir for long-term HSC storage in a quiescent state. …”
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Primary Dural Lymphoma Mimicking En Plaque Cerebellopontine Angle Meningioma by Mei Xu, Ashish Bains, Yuan Rong

“…The tumor histopathology showed a lymphoproliferative disorder immunophenotypically consistent with a low-grade marginal zone lymphoma. Bone marrow and systemic involvements were not identified, and a diagnosis of PDL was established. …”
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