PNPO‐Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β‐Catenin Pathway by Zhendong Deng, Shanliang Sun, Nian Zhou, Yumeng Peng, Long Cheng, Xichao Yu, Yuxia Yuan, Mengjie Guo, Min Xu, Yuexin Cheng, Fan Zhou, Nianguang Li, Ye Yang, Chunyan Gu

“…Abstract Multiple myeloma (MM) is a cancer of plasma cells caused by abnormal gene expression and interactions within the bone marrow (BM) niche. The BM environment significantly influences the progression of MM. …”
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Different modifications of minimally invasive osteosynthesis in pilon fractures: comparative study results by Boris A. Maiorov, Igor G. Belen’kiy, Gennadii D. Sergeev, Kamoliddin K. Gadoev, Mariya A. Sergeeva

“…It also reduces the risk of complications due to increased stability of the fragment fixation and the resistance of the implant-bone system to physiological stress.…”
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Quantitative relationships between elastic modulus of rod and biomechanical properties of transforaminal lumbar interbody fusion: a finite element analysis by Jie Li, Zengfeng Du, Shuai Cao, Teng Lu, Zhongwei Sun, Hongyu Wei, Haopeng Li, Ting Zhang

“…The range of motion (ROM) of the fixed segment, mean strain of the bone graft, and maximum von Mises stresses on the cage, endplate, and posterior fixation system models were calculated. …”
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Ex Vivo Expansion of Murine MSC Impairs Transcription Factor-Induced Differentiation into Pancreatic β-Cells by Dario Gerace, Rosetta Martiniello-Wilks, Rosaline Habib, Binhai Ren, Najah Therese Nassif, Bronwyn Anne O’Brien, Ann Margaret Simpson

“…CD45-/Ly6+ murine MSCs were isolated from the bone marrow of nonobese diabetic (NOD) mice and nucleofected to express the bioluminescent protein, Firefly luciferase (Luc2). …”
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Nonimmune Hydrops Fetalis and Early Skeletal Changes in Congenital Syphilis: Case Series and Review of Literature by Kruti N Shah, Shwetal Bhatt, Vaishali Chanpura

“…The signs of neonatal syphilis, including hepatic and bone dysfunction, and fetal hemolytic anemia, do follow complete recovery with penicillin treatment. …”
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Cranioplasty infection in porous hydroxyapatite: Potential antibacterial properties by Ismail Zaed, Corrado Iaccarino, Francesca Faedo, Laura Grillini, Elisabetta Galassi, Alessandro Dotti, Angelo Nataloni, Francesca Carolina Mannella, Andrea Cardia

“…A variety of biomaterials, from autologous bone to polymethylmetacrylate, polyether ether ketone, titanium, and calcium-based ceramics are used in cranioplasty. …”
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Evaluating Explainable AI Methods in Deep Learning Models for Early Detection of Cerebral Palsy by Kimji N. Pellano, Inga Strumke, Daniel Groos, Lars Adde, Espen F. Alexander Ihlen

“…In contrast, CAM performs better in the Relative Input Stability bone (RISb) metric, which relates to bone stability, and the Relative Representation Stability (RRS) metric, which assesses internal representation robustness. …”
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Differential regulation of apoptosis-related genes during long-term culture and differentiation of canine adipose-derived stem cells - a functional bioinformatical analysis by Maurycy Jankowski, Maurycy Jankowski, Maurycy Jankowski, Katarzyna Stefańska, Michał Suchodolski, Claudia Dompe, Claudia Dompe, Grzegorz Wąsiatycz, Bartosz Kempisty, Bartosz Kempisty, Bartosz Kempisty, Bartosz Kempisty, Michał Nowicki, Magdalena Roszak

“…Their rapid growth, ability to differentiate, and easy extraction with minimal complications make adipose-derived stem cells (ADSCs) a promising option for many treatments, particularly those targeting bone-related diseases. This study analyzed gene expression in canine ADSCs subjected to long-term culture and osteogenic differentiation.MethodsADSCs were isolated from discarded surgical waste and cultured for 14 days with and without differentiation media to assess osteogenic changes. …”
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Accuracy of placement of the glenoid component in reverse shoulder arthroplasty using a custom baseplate for severe glenoid deficiency by Katsumasa Nakazawa, MD, Tomoya Manaka, MD, PhD, Yukihide Minoda, MD, PhD, Nobuyasu Ochiai, MD, PhD, Yasuhiro Nakane, MD, Yoichi Ito, MD, PhD, Yoshihiro Hirakawa, MD, PhD, Ryosuke Iio, MD, Kenta Inagaki, MD, Hiroaki Nakamura, MD, PhD

“…Background: Glenoid bone deficiency can lead to early component loosening and implant failure during reverse total shoulder arthroplasty (rTSA). …”
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In Vivo and In Vitro Study of a Polylactide-Fiber-Reinforced β-Tricalcium Phosphate Composite Cage in an Ovine Anterior Cervical Intercorporal Fusion Model by Janek Frantzén, Aliisa Pälli, Esa Kotilainen, Harri Heino, Bettina Mannerström, Heini Huhtala, Hannu Kuokkanen, George K. Sándor, Kari Leino, Matias Röyttä, Riitta Parkkola, Riitta Suuronen, Susanna Miettinen, Hannu T. Aro, Suvi Haimi

“…The composite implants failed to direct bone growth as desired, whereas the bone contact and the proper integration were evident with controls 6 months after implantation. …”
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Stem cell-derived exosome treatment for acute spinal cord injury: a systematic review and meta-analysis based on preclinical evidence by Chunlin Mou, Ziyao Xia, Ziyao Xia, Ziyao Xia, Xiujuan Wang, Xunan Dai, Jiaxian Wang, Chun Zhang, Chun Zhang, Yongsheng Xu, Yongsheng Xu, Yongsheng Xu

“…Exosomes were derived from bone marrow, adipose tissue, umbilical cord or human placental MSCs. …”
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Inhibition of id-1 reduces osteosarcoma growth and metastasis through mediation of snail by Rongbing Shu, Zhuanyi Yu, Jianmin Wu, Qiuxin Cheng, Zhihao Peng, Huaqiang Zhou, Min Zhao

“…Abstract Objective Osteosarcoma (OS) is a highly invasive bone tumor that frequently metastasizes to the lungs. …”
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Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia by Ashley G. Zhao, Kiran Shah, Julien Freitag, Brett Cromer, Huseyin Sumer

“…With an increasing focus on the large-scale expansion of mesenchymal stem cells (MSCs) required for clinical applications for the treatment of joint and bone diseases such as osteoarthritis, the optimisation of conditions for in vitro MSC expansion requires careful consideration to maintain native MSC characteristics. …”
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The clinical frailty scale is associated with an increased risk of postoperative complications and the development of post-traumatic osteoarthritis in elderly patients with trimall... by Qingsong Zhou, Wei Deng, Ming Zhao, Wei Zhou, Duo Chen, Heng Wang, Shengtao Wang, Hongsheng Yang, Yong Yin

“…Patients with post-traumatic osteoarthritis, bone tumors, bone infection, and other diseases before surgery were excluded. …”
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Assessment of Risk Factors for Fractures in Patients with Type 2 Diabetes over 60 Years Old: A Cross-Sectional Study from Northeast China by Yan Guo, Yingfang Wang, Feng Chen, Jiabei Wang, Difei Wang

“…Our study measured the heel bone mineral density (BMD) and used the timed “up and go” (TUG) test and other indicators. …”
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Comparison of lifetime attributable risk of post-irradiation secondary cancer of boron neutron capture therapy, proton beam therapy, and X-ray therapy for pediatric and adolescent... by Shunsuke Suzuki, Shintaro Shiba, Hiroki Tanaka, Masashi Yamanaka, Kazuki Matsumoto, Koichi Tokuuye, Motoko Omura

“…Results: Statistically significant differences between BNCT vs PBT and XT were confirmed for the brain, bone, soft tissue, and cumulative (P < 0.0001). Significant differences were also observed in PBT and XT, with P < 0.0001 for brain and cumulative, P = 0.0002 for bone, and P = 0.0281 for soft tissue. …”
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The Influence of Vitamin D Receptor Gene Polymorphisms in Spondyloarthritis by Janisleya Silva Ferreira Neves, Jeane Eliete Laguila Visentainer, Denise Manjurma da Silva Reis, Marco Antonio Rocha Loures, Hugo Vicentin Alves, Fernanda Formaggi Lara-Armi, Josiane Bazzo de Alencar, Joana Maira Valentin Zacarias, Ana Maria Sell

“…Spondyloarthritis (SpA) is an inflammatory rheumatic disease related to low bone mineral density. Because vitamin D plays an important role in bone metabolism and immune system modulation, the aim of this study was to evaluate the influence of polymorphisms in vitamin D receptor genes (VDR) in the development of SpA. …”
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The effect of arthroscopic Bankart repair and remplissage procedure on joint range of motion and functional outcomes in anterior shoulder instability by Umut Öktem, Gülfem Ezgi Özaltın, Sinan Yılmaz, İbrahim Bozkurt, Durmuş Ali Öçgüder

“…The Bankart lesion was determined by magnetic resonance imaging, and the amount of glenoid bone loss was determined by computed tomography. …”
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Investigating resistance to 5-Azacytidine and Venetoclax in PDX models of MDS/AML by Petra Bašová, Lubomír Minařík, Lubomír Minařík, Silvia Carina Magalhaes-Novais, Jana Balounová, Zuzana Zemanová, Tatiana Aghová, Martin Špaček, Anna Jonášová, Kristýna Gloc Pimková, Jan Procházka, Radislav Sedláček, Tomáš Stopka, Tomáš Stopka

“…Mouse models that engraft primary AML samples may further advance VEN + AZA resistance research.MethodsWe generated a set of transplantable murine PDX models from MDS/AML patients who developed resistance to VEN + AZA and compared the differences in hematopoiesis of the PDX models with primary bone marrow samples at the genetic level. PDX were created in NSGS mice via intraosseal injection of luciferase-encoding Lentivirus-infected MDS/AML primary cells from patient bone marrow. …”
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Changes in blood glucose and lipid metabolism levels in children with central precocious puberty and its correlation with obesity by Xin Cui, Xin Cui, Xin Sun, Qiubo Li, Zongbo Chen

“…General data [gender, age, bone age, and body mass index (BMI)] were collected. …”
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