Hip Osteonecrosis Is Associated with Increased Plasma IL-33 Level by Jinhui Ma, Wanshou Guo, Zirong Li, Bailiang Wang, Shirui Li, Peng Wang

“…The recently discovered IL-33 as an IL-1 cytokine family member has been proved to be specifically released from osteonecrotic bones. We aimed to investigate the potential role of IL-33 in the development of osteonecrosis of femoral head (ONFH). …”
Get full text

MULTIPLE BURR HOLE AS AN ALTERNATIVE TREATMENT FOR LARGE SCALP DEFECT by Priscilla Valentin N, Iswinarno Doso Saputro

“… • Multiple cranial burr holes is safe, swift and effective for the skull bone expose of the periosteum. Abstract: Introduction: Scalp defect with exposed bones is a serious injury that is often occurred after electrical burn injury. …”
Get full text

Sagittal Craniosynostosis with Uncommon Anatomical Pathologies in a 56-Year-Old Male Cadaver by Andrey Frolov, Craig Lawson, Joshua Olatunde, James T. Goodrich, John R. Martin III

“…The craniotomy was unsuccessful (cephalic index, CI = 56) and resulted in abnormal vertical outgrowth of the craniotomized bone strip. The histological analysis of the latter revealed atypical, noncompensatory massive bone overproduction. …”
Get full text

Gorham Stout syndrome in a pediatric patient. A case report by Ariel Moya Machado, Leidelén Esquivel Sosa, Yisel González Ríos

“…It is a clinical picture characterized by the progressive destruction of bone tissue and vascular proliferation, with angiomatosis and bone lymphangiomatosis that produces a progressive osteolysis of the skeleton, with loss of bone mass in the affected areas. …”
Get full text

Metformin Facilitates Osteoblastic Differentiation and M2 Macrophage Polarization by PI3K/AKT/mTOR Pathway in Human Umbilical Cord Mesenchymal Stem Cells by Min Shen, Huihui Yu, Yunfeng Jin, Jiahang Mo, Jingni Sui, Xiaohan Qian, Tong Chen

“…The immune system is a key player in regulating bone remodeling. In recent years, the association between the immune system and bone metabolism has become an increasing focus of interest. …”
Get full text

Osteomyelitis in Cat-Scratch Disease: A Never-Ending Dilemma—A Case Report and Literature Review by D. Donà, L. Nai Fovino, E. Mozzo, G. Cabrelle, G. Bordin, R. Lundin, C. Giaquinto, T. Zangardi, O. Rampon

“…Osteoarticular pain or limitation during cat-scratch disease in children should always be investigated for bone spreading. Owing to good prognosis, invasive procedures to obtain the bone material should be avoided. …”
Get full text

Neglected Forearm Fractures and Its Outcome Following Mediolateral Plate Osteosynthesis: A Retrospective Case Series by Sitsabesan Chokkalingam, Ashok T Ramanathan, Gopinath Menon

“…Background: Displaced both bone forearm injuries are essential fractures for fixation. …”
Get full text

Nanocomposite magnetic hydrogel with dual anisotropic properties induces osteogenesis through the NOTCH-dependent pathways by Shijia Tang, Yue Yan, Xiaoli Lu, Peng Wang, Xueqin Xu, Ke Hu, Sen Yan, Zhaobin Guo, Xiao Han, Feimin Zhang, Ning Gu

“…In addition, the present study revealed that the dual anisotropic properties of the MAH activated the NOTCH1/2 pathway by upregulating SNHG5 and downstream SIRT6, which modulates the level of NOTCH1/2 by antagonizing DNMT1 protein stability, ultimately inducing the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Furthermore, the MAH, MIH, and PGH were tested for in vivo bone regeneration in rabbits with femur defects, and the results demonstrated that the MAH effectively stimulated bone regeneration. …”
Get full text

Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation by Lei Sun, Jinhao Zhang, Zhikai Xiahou, Zhenzhen Zhao, Yanchen Liang

“…BackgroundOsteosarcoma (OS) is one of the most common primary malignant bone tumors, primarily originating from mesenchymal tissue. …”
Get full text

BIOMECHANICAL EVALUATIONS OF IMPLANTO-PROSTHETIC RESTORATIONS by Resmerita Andreea, Cretu Cosmin Ionut, Scheuleac Alexandra, Agop-Forna Doriana, Adam Eduard, Forna Norina

“…Aim of the study: This study aims to evaluate the biomechanical effects of various prosthetic configurations in cases of severe bone atrophy. Short dental implants (≤8 mm) and narrow diameter implants (NDI) ≤3.5 mm were proposed as alternatives to bone augmentation procedures, showing encouraging short-term survival rates. …”
Get full text

Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

“…At baseline, participants will undergo a spine X-ray, and have bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) at the spine and hip. …”
Get full text

Influencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective study by Hongyu Jiang, Xueke Chang, Fubin Yu, Ming Zhang, Yifan Liu, Jianzhi Man, Kangshu Guo, Hongzheng Meng, Wenqiang Zhang

Get full text

Influence of different polymeric materials of implant and attachment on stress distribution in implant-supported overdentures: a three-dimensional finite element study by Sherif Elsayed, Yousra Ahmed, Mohamed I. El-Anwar, Enas Elddamony, Reem Ashraf

“…Aim of study Assessment of stress distribution in polymeric prosthetic components and bone around polymeric implants, in case of implant-supported mandibular overdenture. …”
Get full text

Role of CX3CL1/CX3CR1 Signaling Axis Activity in Osteoporosis by Piotr Wojdasiewicz, Pawel Turczyn, Barbara Dobies-Krzesniak, Justyna Frasunska, Beata Tarnacka

“…The present study, based on world literature review, sums and describes convincing evidences of a significant role of the CX3CL1/CX3CR1 axis in processes leading to bone mineral density (BMD) reduction. The CX3CL1/CX3CR1 axis plays a principal role in osteoclast maturation and binding them with immune cells to the surface of the bone tissue. …”
Get full text

Peripheral nerves modulate the peri-implant osteogenesis under type 2 diabetes through exosomes derived from schwann cells via miR-15b-5p/Txnip signaling axis by Yingying Wang, Fang Qu, Yaqin Wu, Kengliang Lan, Yingyi Shen, Ziang Wu, Qi Zhong, Ximeng Cao, Zhen Fan, Chun Xu

“…Furthermore, normal SCs exosomes improved bone parameters around dental implants in T2DM rats. …”
Get full text

Engineered macrophage nanoparticles enhance microwave ablation efficacy in osteosarcoma via targeting the CD47-SIRPα Axis: A novel Biomimetic immunotherapeutic approach by Xiongfa Ji, Xin Qian, Guowen Luo, Wenjie Yang, Wenhan Huang, Zehua Lei, Jiaqi Zhou, Guoqing Zhong, Jielong Zhou, Nan Liu, Limin Ma, Mei Li, Xiangmei Liu, Shuilin Wu, Yu Zhang

“…Osteosarcoma (OS) is a lethal bone tumor that primarily affects adolescents. OS is characterized by a high incidence of recurrence following surgical intervention, which is attributed to the presence of residual microscopic disease. …”
Get full text

A Clinical and Radiographic Evaluation of Zirconia Dental Implants: 10-Year Follow-Up by Andrea Enrico Borgonovo, Susanna Ferrario, Carlo Maiorana, Virna Vavassori, Rachele Censi, Dino Re

“…The aim is to evaluate the survival and success rates, as well as the marginal bone loss (MBL) and periodontal indexes, of zirconia implants with 10-year follow-up. …”
Get full text

Treatment of periodontal infrabony defect using particulate dentin graft and recombinant human platelet-derived growth factor by Vishal Garg, Amit Bhardwaj, Kirti Chawla

“…Periodontal bone defects pose significant challenges in dentistry, necessitating effective treatment strategies. …”
Get full text

Abnormal Decrease of Macrophage ALKBH5 Expression Causes Abnormal Polarization and Inhibits Osteoblast Differentiation by Junquan Weng, Haidong Fan, Huijuan Liu, Su Tang, Yuyan Zheng

“…Peri-implant tissue inflammation is an inflammatory injury that occurs in the soft and hard tissues surrounding the implant and is the main cause of short- or long-term failure of implant prosthetic restorations, which is compounded by bone loss and bone destruction in the alveolar bone of diabetes patients with peri-implantitis. …”
Get full text

Leukotriene inhibition in hamster periodontitis. A histochemical and morphometric study by B. Baroukh, J. L. Saffar

“…The effects of leukotriene (LT) inhibition on gingival and adjacent bone compartments were assessed by using phenidone (100 mg/kg/d) and ketoconazole (50 mg/kg/d) given for 4 weeks to periodontitis-affected hamsters. …”
Get full text